相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。A Phase Ib/II Study of the JAK1 Inhibitor, Itacitinib, plus nab-Paclitaxel and Gemcitabine in Advanced Solid Tumors
Gregory L. Beatty et al.
ONCOLOGIST (2019)
MicroRNA-503-5p Inhibits the CD97-Mediated JAK2/STAT3 Pathway in Metastatic or Paclitaxel-Resistant Ovarian Cancer Cells
Ga Bin Park et al.
NEOPLASIA (2019)
Inhibition of Heat Shock Protein 90 suppresses TWIST1 Transcription
Kay Yi Chong et al.
MOLECULAR PHARMACOLOGY (2019)
Role of cancer-associated fibroblasts in tumor structure, composition and the microenvironment in ovarian cancer
Wei Sun et al.
ONCOLOGY LETTERS (2019)
The Role of Epithelial-to-Mesenchymal Plasticity in Ovarian Cancer Progression and Therapy Resistance
Nele Loret et al.
CANCERS (2019)
The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease
Lindsay Kosack et al.
CANCER CELL (2019)
Celastrol strongly inhibits proliferation, migration and cancer stem cell properties through suppression of Pin1 in ovarian cancer cells
Xiaojing Li et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2019)
Leukemia inhibitory factor functions in parallel with interleukin-6 to promote ovarian cancer growth
Karen McLean et al.
ONCOGENE (2019)
Direct Targeting Options for STAT3 and STAT5 in Cancer
Anna Orlova et al.
CANCERS (2019)
MicroRNA-519a inhibits the proliferation and promotes the apoptosis of ovarian cancer cells through targeting signal transducer and activator of transcription 3
Fei Tian et al.
EXPERIMENTAL AND THERAPEUTIC MEDICINE (2018)
Differential role of Interleukin-1 and Interleukin-6 in K-Ras-driven pancreatic carcinoma undergoing mesenchymal transition
Imran Siddiqui et al.
ONCOIMMUNOLOGY (2018)
Co-culture of ovarian cancer stem-like cells with macrophages induced SKOV3 cells stemness via IL-8/STAT3 signaling
Yingxia Ning et al.
BIOMEDICINE & PHARMACOTHERAPY (2018)
Mutations in the signal transducer and activator of transcription family of genes in cancer
Nahid Shahmarvand et al.
CANCER SCIENCE (2018)
AKT2 contributes to increase ovarian cancer cell migration and invasion through the AKT2-PKM2-STAT3/NF-κB axis
Bin Zheng et al.
CELLULAR SIGNALLING (2018)
Pterostilbene Suppresses Ovarian Cancer Growth via Induction of Apoptosis and Blockade of Cell Cycle Progression Involving Inhibition of the STAT3 Pathway
Wei Wen et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Protein kinase A-mediated phosphorylation regulates STAT3 activation and oncogenic EZH2 activity
Ali R. Ozes et al.
ONCOGENE (2018)
Hypoxia-induced exosomes contribute to a more aggressive and chemoresistant ovarian cancer phenotype: a novel mechanism linking STAT3/Rab proteins
Kalpana Deepa Priya Dorayappan et al.
ONCOGENE (2018)
Autocrine activation of JAK2 by IL-11 promotes platinum drug resistance
Wei Zhou et al.
ONCOGENE (2018)
CAFs enhance paclitaxel resistance by inducing EMT through the IL-6/JAK2/STAT3 pathway
Linlin Wang et al.
ONCOLOGY REPORTS (2018)
Advances of exosome in the development of ovarian cancer and its diagnostic and therapeutic prospect
Jiayu Shen et al.
ONCOTARGETS AND THERAPY (2018)
Influence of c-Src on hypoxic resistance to paclitaxel in human ovarian cancer cells and reversal of FV-429
Qinglong Guo et al.
CELL DEATH & DISEASE (2018)
JAK2/STAT3 pathway as a therapeutic target in ovarian cancers
Tomoyuki Yoshikawa et al.
ONCOLOGY LETTERS (2018)
Ruxolitinib synergistically enhances the anti-tumor activity of paclitaxel in human ovarian cancer
Ernest S. Han et al.
Oncotarget (2018)
Momelotinib decreased cancer stem cell associated tumor burden and prolonged disease-free remission period in a mouse model of human ovarian cancer
Emily Chan et al.
Oncotarget (2018)
3,3′-Diindolylmethane suppresses ovarian cancer cell viability and metastasis and enhances chemotherapy sensitivity via STAT3 and Akt signaling in vitro and in vivo
Minghua Zou et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2018)
STAT3 regulated miR-216a promotes ovarian cancer proliferation and cisplatin resistance
Pengfei Jin et al.
BIOSCIENCE REPORTS (2018)
The BET bromodomain inhibitor i-BET151 impairs ovarian cancer metastasis and improves antitumor immunity
Ai Liu et al.
CELL AND TISSUE RESEARCH (2018)
Cryptotanshinone suppresses cell proliferation and glucose metabolism via STAT3/SIRT3 signaling pathway in ovarian cancer cells
Yufei Yang et al.
CANCER MEDICINE (2018)
The Long Noncoding RNA MEG3 and its Target miR-147 Regulate JAK/STAT Pathway in Advanced Chronic Myeloid Leukemia
Zi-ye Li et al.
EBIOMEDICINE (2018)
Exosomes Released from Tumor-Associated Macrophages Transfer miRNAs That Induce a Treg/Th17 Cell Imbalance in Epithelial Ovarian Cancer
Jieru Zhou et al.
CANCER IMMUNOLOGY RESEARCH (2018)
Exosomes Promote Ovarian Cancer Cell Invasion through Transfer of CD44 to Peritoneal Mesothelial Cells
Koji Nakamura et al.
MOLECULAR CANCER RESEARCH (2017)
Cinnamon extract reduces VEGF expression via suppressing HIF-1 gene expression and inhibits tumor growth in mice
Keqiang Zhang et al.
MOLECULAR CARCINOGENESIS (2017)
Elevated STAT3 expression in ovarian cancer ascites promotes invasion and metastasis: a potential therapeutic target
U. Saini et al.
ONCOGENE (2017)
Do STAT3 inhibitors have potential in the future for cancer therapy?
Andrea L. A. Wong et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2017)
Targeting STAT3 by HO3867 induces apoptosis in ovarian clear cell carcinoma
Kristin Bixel et al.
INTERNATIONAL JOURNAL OF CANCER (2017)
Lysyl Oxidase 3 Is a Dual-Specificity Enzyme Involved in STAT3 Deacetylation and Deacetylimination Modulation
Li Ma et al.
MOLECULAR CELL (2017)
JAK inhibition as a therapeutic strategy for immune and inflammatory diseases
Daniella M. Schwartz et al.
NATURE REVIEWS DRUG DISCOVERY (2017)
Leptin receptor signaling via Janus kinase 2/Signal transducer and activator of transcription 3 impacts on ovarian cancer cell phenotypes
Janani Kumar et al.
ONCOTARGET (2017)
IGF-1 induces the epithelial-mesenchymal transition via Stat5 in hepatocellular carcinoma
Chuanzong Zhao et al.
ONCOTARGET (2017)
STAT3 is required for MiR-17-5p-mediated sensitization to chemotherapy-induced apoptosis in breast cancer cells
Xing-Hua Liao et al.
ONCOTARGET (2017)
IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway
Xiongyan Wu et al.
ONCOTARGET (2017)
Tumor-associated macrophages promote neuroblastoma via STAT3 phosphorylation and up-regulation of c-MYC
Michael D. Hadjidaniel et al.
ONCOTARGET (2017)
Adipose Stromal Cells from Visceral and Subcutaneous Fat Facilitate Migration of Ovarian Cancer Cells via IL-6/JAK2/STAT3 Pathway
Boyun Kim et al.
CANCER RESEARCH AND TREATMENT (2017)
Phosphorylation of STAT3 at Tyr705 regulates MMP-9 production in epithelial ovarian cancer
Zan-Hui Jia et al.
PLOS ONE (2017)
Leptin OB3 peptide suppresses leptin-induced signaling and progression in ovarian cancer cells
Yu-Tang Chin et al.
JOURNAL OF BIOMEDICAL SCIENCE (2017)
The STAT3-miRNA-92-Wnt Signaling Pathway Regulates Spheroid Formation and Malignant Progression in Ovarian Cancer
Min-Wei Chen et al.
CANCER RESEARCH (2017)
Antitumor effects of interleukin-6 (IL-6)/interleukin-6 receptor (IL-6R) signaling pathway inhibition in clear cell carcinoma of the ovary
Nozomu Yanaihara et al.
MOLECULAR CARCINOGENESIS (2016)
IL6-induced metastasis modulators p-STAT3, MMP-2 and MMP-9 are targets of 3,3′-diindolylmethane in ovarian cancer cells
Minghua Zou et al.
CELLULAR ONCOLOGY (2016)
The new WHO classification of ovarian, fallopian tube, and primary peritoneal cancer and its clinical implications
Ivo Meinhold-Heerlein et al.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS (2016)
Cancer-associated fibroblasts attenuate Cisplatin-induced apoptosis in ovarian cancer cells by promoting STAT3 signaling
Huan Yan et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
miRNA-133b and miRNA-135a induce apoptosis via the JAK2/STAT3 signaling pathway in human renal carcinoma cells
Wenbin Zhou et al.
BIOMEDICINE & PHARMACOTHERAPY (2016)
EZH2 phosphorylation by JAK3 mediates a switch to noncanonical function in natural killer/T-cell lymphoma
Junli Yan et al.
BLOOD (2016)
Anticancer potential of diarylidenyl piperidone derivatives, HO-4200 and H-4318, in cisplatin resistant primary ovarian cancer
Adam C. ElNaggar et al.
CANCER BIOLOGY & THERAPY (2016)
The molecular mechanism of action of superactive human leptin antagonist (SHLA) and quadruple leptin mutein Lan-2 on human ovarian epithelial cell lines
Elzbieta Fiedor et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2016)
Ovarian cancer stem-like cells differentiate into endothelial cells and participate in tumor angiogenesis through autocrine CCL5 signaling
Shu Tang et al.
CANCER LETTERS (2016)
Prolactin inhibits a major tumor-suppressive function of wild type BRCA1
Kuan-Hui Ethan Chen et al.
CANCER LETTERS (2016)
Resistance to Anti-VEGF Therapy Mediated by Autocrine IL6/STAT3 Signaling and Overcome by IL6 Blockade
Alexandra Eichten et al.
CANCER RESEARCH (2016)
IL-6/STAT3 Plays a Regulatory Role in the Interaction Between Pancreatic Stellate Cells and Cancer Cells
Shin Hamada et al.
DIGESTIVE DISEASES AND SCIENCES (2016)
High expression of Mcl-1L via the MEK-ERK-phospho-STAT3 (Ser727) pathway protects melanocytes and melanoma from UVB-induced apoptosis
Takeshi Fukumoto et al.
GENES TO CELLS (2016)
The biological significance and clinical applications of exosomes in ovarian cancer
Kalpana Deepa Priya Dorayappan et al.
GYNECOLOGIC ONCOLOGY (2016)
Cisplatin-induced CCL5 secretion from CAFs promotes cisplatin-resistance in ovarian cancer via regulation of the STAT3 and PI3K/Akt signaling pathways
Bo Zhou et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2016)
Tumor-associated macrophages drive spheroid formation during early transcoelomic metastasis of ovarian cancer
Mingzhu Yin et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
Exosome-Mediated Metastasis: From Epithelial-Mesenchymal Transition to Escape from Immunosurveillance
Nicholas Syn et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2016)
NANOG regulates epithelial-mesenchymal transition and chemoresistance through activation of the STAT3 pathway in epithelial ovarian cancer
Suqing Liu et al.
TUMOR BIOLOGY (2016)
Autocrine interleukin-23 promotes self-renewal of CD133+ ovarian cancer stem-like cells
Dan Wang et al.
ONCOTARGET (2016)
Malignant ascites enhances migratory and invasive properties of ovarian cancer cells with membrane bound IL-6R in vitro
Soochi Kim et al.
ONCOTARGET (2016)
Direct Upregulation of STAT3 by MicroRNA-551b-3p Deregulates Growth and Metastasis of Ovarian Cancer
Pradeep Chaluvally-Raghavan et al.
CELL REPORTS (2016)
The biology and function of fibroblasts in cancer
Raghu Kalluri
NATURE REVIEWS CANCER (2016)
Jak2-Stat5a/b Signaling Induces Epithelial-to-Mesenchymal Transition and Stem-Like Cell Properties in Prostate Cancer
Pooja G. Talati et al.
AMERICAN JOURNAL OF PATHOLOGY (2015)
A phase I trial combining carboplatin/doxorubicin with tocilizumab, an anti-IL-6R monoclonal antibody, and interferon-α2b in patients with recurrent epithelial ovarian cancer
E. M. Dijkgraaf et al.
ANNALS OF ONCOLOGY (2015)
Obesity and survival among women with ovarian cancer: results from the Ovarian Cancer Association Consortium
C. M. Nagle et al.
BRITISH JOURNAL OF CANCER (2015)
Erythropoietin Stimulates Tumor Growth via EphB4
Sunila Pradeep et al.
CANCER CELL (2015)
The Mutant KRAS Gene Up-regulates BCL-XL Protein via STAT3 to Confer Apoptosis Resistance That Is Reversed by BIM Protein Induction and BCL-XL Antagonism
Aziz Zaanan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
STAT3 cooperates with Twist to mediate epithelial-mesenchymal transition in human hepatocellular carcinoma cells
Chuanhai Zhang et al.
ONCOLOGY REPORTS (2015)
STAT3 Decoy Oligodeoxynucleotides-Loaded Solid Lipid Nanoparticles Induce Cell Death and Inhibit Invasion in Ovarian Cancer Cells
Yanhui Ma et al.
PLOS ONE (2015)
Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency
Hongwei Chen et al.
NATURE COMMUNICATIONS (2015)
STAT5 Reactivation by Catechin Modulates H2O2-Induced Apoptosis Through miR-182/FOXO1 Pathway in SK-N-MC Cells
Ali Gheysarzadeh et al.
CELL BIOCHEMISTRY AND BIOPHYSICS (2015)
被撤回的出版物: Synergistic effects of eukaryotic co-expression plasmid-based STAT3-specific siRNA and LKB1 on ovarian cancer in vitro and in vivo (Retracted article. See vol. 46, 2021)
Yuan Pan et al.
ONCOLOGY REPORTS (2015)
Role of the interleukin 6 receptor family in epithelial ovarian cancer and its clinical implications
Janani Kumar et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2014)
Inhibition of the JAK2/STAT3 pathway in ovarian cancer results in the loss of cancer stem cell-like characteristics and a reduced tumor burden
Khalid Abubaker et al.
BMC CANCER (2014)
Granulocyte colony-stimulating factor receptor signalling via Janus kinase 2/signal transducer and activator of transcription 3 in ovarian cancer
J. Kumar et al.
BRITISH JOURNAL OF CANCER (2014)
Interleukin-6 released by colon cancer-associated fibroblasts is critical for tumour angiogenesis: anti-interleukin-6 receptor antibody suppressed angiogenesis and inhibited tumour-stroma interaction
T. Nagasaki et al.
BRITISH JOURNAL OF CANCER (2014)
MLS-2384, a new 6-bromoindirubin derivative with dual JAK/Src kinase inhibitory activity, suppresses growth of diverse cancer cells
Lucy Liu et al.
CANCER BIOLOGY & THERAPY (2014)
Blockage of STAT3 Signaling Pathway with a Decoy Oligodeoxynucleotide Inhibits Growth of Human Ovarian Cancer Cells
Ming Liu et al.
CANCER INVESTIGATION (2014)
N-myc downstream-regulated gene 2 (NDRG2) suppresses the epithelial-mesenchymal transition (EMT) in breast cancer cells via STAT3/Snail signaling
Myung-Jin Kim et al.
CANCER LETTERS (2014)
Multiple receptor tyrosine kinases converge on microRNA-134 to control KRAS, STAT5B, and glioblastoma
Y. Zhang et al.
CELL DEATH AND DIFFERENTIATION (2014)
Targeting JAK1/STAT3 Signaling Suppresses Tumor Progression and Metastasis in a Peritoneal Model of Human Ovarian Cancer
Wei Wen et al.
MOLECULAR CANCER THERAPEUTICS (2014)
Mutant B-RAF-Mcl-1 survival signaling depends on the STAT3 transcription factor
T. M. Becker et al.
ONCOGENE (2014)
A high M1/M2 ratio of tumor-associated macrophages is associated with extended survival in ovarian cancer patients
Meiying Zhang et al.
JOURNAL OF OVARIAN RESEARCH (2014)
Tumor-Associated Macrophages as Major Players in the Tumor Microenvironment
Theerawut Chanmee et al.
CANCERS (2014)
Targeted disruption of the JAK2/STAT3 pathway in combination with systemic administration of paclitaxel inhibits the priming of ovarian cancer stem cells leading to a reduced tumor burden
Khalid Abubaker et al.
FRONTIERS IN ONCOLOGY (2014)
Antiangiogenic effects of ganetespib in colorectal cancer mediated through inhibition of HIF-1α and STAT-3
Purnachandra Nagaraju Ganji et al.
ANGIOGENESIS (2013)
Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia
Hanna L. M. Rajala et al.
BLOOD (2013)
Abrogation of constitutive Stat3 activity circumvents cisplatin resistant ovarian cancer
Teng Ji et al.
CANCER LETTERS (2013)
The upregulation of signal transducer and activator of transcription 5-dependent microRNA-182 and microRNA-96 promotes ovarian cancer cell proliferation by targeting forkhead box O3 upon leptin stimulation
Xiaofei Xu et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2013)
Epithelial to Mesenchymal Transition Promotes Breast Cancer Progression via a Fibronectin-dependent STAT3 Signaling Pathway
Nikolas Balanis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Efficient inhibition of intraperitoneal ovarian cancer growth in nude mice by liposomal delivery of short hairpin RNA against STAT3
Qingyuan Jiang et al.
JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH (2013)
STAT3 mutations are frequent in CD30+T-cell lymphomas and T-cell large granular lymphocytic leukemia
R. S. Ohgami et al.
LEUKEMIA (2013)
Stat3-coordinated Lin-28-let-7-HMGA2 and miR-200-ZEB1 circuits initiate and maintain oncostatin M-driven epithelial-mesenchymal transition
L. Guo et al.
ONCOGENE (2013)
AZD1480: A Phase I Study of a Novel JAK2 Inhibitor in Solid Tumors
Elizabeth R. Plimack et al.
ONCOLOGIST (2013)
The Ratios of CD8+ T Cells to CD4+ CD25+ FOXP3+ and FOXP3- T Cells Correlate with Poor Clinical Outcome in Human Serous Ovarian Cancer
Claudia C. Preston et al.
PLOS ONE (2013)
Expression of M2-Polarized Macrophages is Associated with Poor Prognosis for Advanced Epithelial Ovarian Cancer
Chunyan Lan et al.
TECHNOLOGY IN CANCER RESEARCH & TREATMENT (2013)
The IL-6/JAK/Stat3 Feed-Forward Loop Drives Tumorigenesis and Metastasis
Qing Chang et al.
NEOPLASIA (2013)
Effects of erythropoietin receptors and erythropoiesis-stimulating agents on disease progression in cancer
M. Aapro et al.
BRITISH JOURNAL OF CANCER (2012)
Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
Douglas Hanahan et al.
CANCER CELL (2012)
Ovarian cancer: Stat3, RhoA and IGF-IR as therapeutic targets
Caroline Gest et al.
CANCER LETTERS (2012)
Leukotriene B4 Receptor-2 Promotes Invasiveness and Metastasis of Ovarian Cancer Cells through Signal Transducer and Activator of Transcription 3 (STAT3)-dependent Up-regulation of Matrix Metalloproteinase 2
Ji-Min Seo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
The tumor microenvironment at a glance
Frances R. Balkwill et al.
JOURNAL OF CELL SCIENCE (2012)
Somatic STAT3 Mutations in Large Granular Lymphocytic Leukemia
Hanna L. M. Koskela et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Ten-Year Relative Survival for Epithelial Ovarian Cancer
Lauren A. Baldwin et al.
OBSTETRICS AND GYNECOLOGY (2012)
Hyperactive EGF receptor, Jaks and Stat3 signaling promote enhanced colony-forming ability, motility and migration of cisplatin-resistant ovarian cancer cells
P. Yue et al.
ONCOGENE (2012)
Isolation and Characterization of Tumor Cells from the Ascites of Ovarian Cancer Patients: Molecular Phenotype of Chemoresistant Ovarian Tumors
Ardian Latifi et al.
PLOS ONE (2012)
STAT5b as Molecular Target in Pancreatic Cancer-Inhibition of Tumor Growth, Angiogenesis, and Metastases
Christian Moser et al.
NEOPLASIA (2012)
Regulation of Janus-activated kinase-2 (JAK2) by diindolylmethane in ovarian cancer in vitro and in vivo
Prabodh K. Kandala et al.
DRUG DISCOVERIES AND THERAPEUTICS (2012)
HO-3867, a curcumin analog, sensitizes cisplatin-resistant ovarian carcinoma, leading to therapeutic synergy through STAT3 inhibition
Karuppaiyah Selvendiran et al.
CANCER BIOLOGY & THERAPY (2011)
Stat3 and MMP7 Contribute to Pancreatic Ductal Adenocarcinoma Initiation and Progression
Akihisa Fukuda et al.
CANCER CELL (2011)
Estrogen receptor alpha pathway is involved in leptin-induced ovarian cancer cell growth
Jung-Hye Choi et al.
CARCINOGENESIS (2011)
IL6-STAT3-HIF Signaling and Therapeutic Response to the Angiogenesis Inhibitor Sunitinib in Ovarian Clear Cell Cancer
Michael S. Anglesio et al.
CLINICAL CANCER RESEARCH (2011)
Interleukin-6 as a Therapeutic Target in Human Ovarian Cancer
Jermaine Coward et al.
CLINICAL CANCER RESEARCH (2011)
Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2
Malay Mandal et al.
NATURE IMMUNOLOGY (2011)
Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
Kristin M. Nieman et al.
NATURE MEDICINE (2011)
Knockdown of stat3 expression by RNAi inhibits in vitro growth of human ovarian cancer
Shu-Hua Zhao et al.
RADIOLOGY AND ONCOLOGY (2011)
Oxygenation inhibits ovarian tumor growth by downregulating STAT3 and cyclin-D1 expressions
Karuppaiyah Selvendiran et al.
CANCER BIOLOGY & THERAPY (2010)
Overexpression of EZH2 contributes to acquired cisplatin resistance in ovarian cancer cells in vitro and in vivo
Sha Hu et al.
CANCER BIOLOGY & THERAPY (2010)
Role of STAT3 decoy oligodeoxynucleotides on cell invasion and chemosensitivity in human epithelial ovarian cancer cells
Xiaolei Zhang et al.
CANCER GENETICS AND CYTOGENETICS (2010)
Involvement of M2-polarized macrophages in the ascites from advanced epithelial ovarian carcinoma in tumor progression via Stat3 activation
Kiyomi Takaishi et al.
CANCER SCIENCE (2010)
Effects of Siltuximab on the IL-6-Induced Signaling Pathway in Ovarian Cancer
Yuqi Guo et al.
CLINICAL CANCER RESEARCH (2010)
Curcumin Suppresses Constitutive Activation of STAT-3 by Up-Regulating Protein Inhibitor of Activated STAT-3 (PIAS-3) in Ovarian and Endometrial Cancer Cells
Manush Saydmohammed et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2010)
Enhancer of Zeste Homolog 2 Promotes the Proliferation and Invasion of Epithelial Ovarian Cancer Cells
Hua Li et al.
MOLECULAR CANCER RESEARCH (2010)
Anticancer Efficacy of a Difluorodiarylidenyl Piperidone (HO-3867) in Human Ovarian Cancer Cells and Tumor Xenografts
Karuppaiyah Selvendiran et al.
MOLECULAR CANCER THERAPEUTICS (2010)
Oncoproteomic Analysis Reveals Co-Upregulation of RELA and STAT5 in Carboplatin Resistant Ovarian Carcinoma
Natini Jinawath et al.
PLOS ONE (2010)
Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial-mesenchymal transition in ovarian carcinomas
M. Colomiere et al.
BRITISH JOURNAL OF CANCER (2009)
Enhancement of TRAIL cytotoxicity by AG-490 in human ALL cells is characterized by downregulation of cIAP-1 and cIAP-2 through inhibition of Jak2/Stat3
Paola Lanuti et al.
CELL RESEARCH (2009)
Mutations in the KRAS gene in ovarian tumors
Bozena Dobrzycka et al.
FOLIA HISTOCHEMICA ET CYTOBIOLOGICA (2009)
Multicellular spheroids in ovarian cancer metastases: Biology and pathology
Kristy Shield et al.
GYNECOLOGIC ONCOLOGY (2009)
Hypoxia induces chemoresistance in ovarian cancer cells by activation of signal transducer and activator of transcription 3
Karuppaiyah Selvendiran et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
Evaluation of New Platinum-Based Treatment Regimens in Advanced-Stage Ovarian Cancer: A Phase III Trial of the Gynecologic Cancer InterGroup
Michael A. Bookman et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
Constitutive activation of signal transducer and activator of transcription 3 in epithelial ovarian carcinoma
Hao Min et al.
JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH (2009)
Overexpression of leptin receptor predicts an unfavorable outcome in Middle Eastern ovarian cancer
Shahab Uddin et al.
MOLECULAR CANCER (2009)
STATs in cancer inflammation and immunity: a leading role for STAT3
Hua Yu et al.
NATURE REVIEWS CANCER (2009)
Co-overexpression of Janus kinase 2 and signal transducer and activator of transcription 5a promotes differentiation of mammary cancer cells through reversal of epithelial-mesenchymal transition
Ahmed S. Sultan et al.
CANCER SCIENCE (2008)
Histologic subtypes of ovarian carcinoma: An overview
Robert A. Soslow
INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY (2008)
Hyaluronan-CD44 interaction activates stem cell marker Nanog, Stat-3-mediated MDR1 gene expression, and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells
Lilly Y. W. Bourguignon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Generation and regulation of human CD4+ IL-17-producing T cells in ovarian cancer
Yoshihiro Miyahara et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Comparison of STAT3 with HIF-1alpha, Ob and ObR expressions in human endometrioid adenocarcinomas
Andrzej Wincewicz et al.
TISSUE & CELL (2008)
Neuroendocrine modulation of signal transducer and activator of transcription-3 in ovarian cancer
Charles N. Landen et al.
CANCER RESEARCH (2007)
An in vivo requirement for STAT3 signaling in TH17 development and TH17-dependent autoimmunity1
Timothy J. Harris et al.
JOURNAL OF IMMUNOLOGY (2007)
Metastatic patterns at autopsy in patients with ovarian carcinoma
Uwe Gueth et al.
CANCER (2007)
STAT3 regulates cytokine-mediated generation of inflammatory helper T cells
Xuexian O. Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer
Junzo Hamanishi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
The adaptive immunologic microenvironment in colorectal cancer: A novel perspective
Jerome Galon et al.
CANCER RESEARCH (2007)
The role of constitutively active signal transducer and activator of transcription 3 in ovarian turnorigenesis and prognosis
Daniel G. Rosen et al.
CANCER (2006)
Differential express-ion of STAT5 and Bcl-xL, and high expression of Neu and STAT3 in non-small-cell lung carcinoma
S. G. Sanchez-Ceja et al.
LUNG CANCER (2006)
Effect of obesity on survival in epithelial ovarian cancer
James C. Pavelka et al.
CANCER (2006)
IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo
Emmanuel Zorn et al.
BLOOD (2006)
Loss of SOCS3 in T helper cells resulted in reduced immune responses and hyperproduction of interleukin 10 and transforming growth factor-β1
I Kinjyo et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma
I Kryczek et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Activation of Stat3 in human melanoma promotes brain metastasis
TX Xie et al.
CANCER RESEARCH (2006)
Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer
E Sato et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
STAT3-mediated transcription of Bcl-2, Mcl-1 and c-lAP2 prevents apoptosis in polyamine-depleted cells
S Bhattacharya et al.
BIOCHEMICAL JOURNAL (2005)
Interleukin-6, secreted by human ovarian carcinoma cells, is a potent proangiogenic cytokine
MB Nilsson et al.
CANCER RESEARCH (2005)
Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity
M Kortylewski et al.
NATURE MEDICINE (2005)
IFN-γ, controls the generation/activation of CD4+CD25+ regulatory T cells in antitumor immune response
H Nishikawa et al.
JOURNAL OF IMMUNOLOGY (2005)
Distinct and overlapping roles of interleukin-10 and CD25+ regulatory T cells in the inhibition of antitumor CD8 T-cell responses
C Dercamp et al.
CANCER RESEARCH (2005)
Expression of activated signal transducer and activator of transcription 3 predicts expression of vascular endothelial growth factor in and angiogenic phenotype of human gastric cancer
WD Gong et al.
CLINICAL CANCER RESEARCH (2005)
Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis
TX Xie et al.
ONCOGENE (2004)
Ovarian carcinoma cells inhibit T cell proliferation:: suppression of IL-2 receptor β and γ expression and their JAK-STAT signaling pathway
H Wang et al.
LIFE SCIENCES (2004)
The stats of cancer - New molecular targets come of age
H Yu et al.
NATURE REVIEWS CANCER (2004)
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
TJ Curiel et al.
NATURE MEDICINE (2004)
VEGF, VEGFRs expressions and activated STATs in ovarian epithelial carcinoma
HZ Chen et al.
GYNECOLOGIC ONCOLOGY (2004)
Modulation of Janus kinase 2 by p53 in ovarian cancer cells
T Reid et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Vascular endothelial growth factor (VEGF) and ovarian carcinoma cell supernatant activate signal transducers and activators of transcription (STATs) via VEGF receptor-2 (KDR) in human hemopoietic progenitor cells
F Ye et al.
GYNECOLOGIC ONCOLOGY (2004)
Activated signal transducer and activator of transcription (STAT) 3: Localization in focal adhesions and function in ovarian cancer cell motility
DL Silver et al.
CANCER RESEARCH (2004)
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-β induction of transcription factor Foxp3
WJ Chen et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Stat3 protects against Fas-induced liver injury by redox-dependent and -independent mechanisms
S Haga et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Activation of Stat3 by receptor tyrosine kinases and cytokines regulates survival in human non-small cell carcinoma cells
LX Song et al.
ONCOGENE (2003)
Interleukin-6 promotes cervical tumor growth by VEGF-dependent angiogenesis via a STAT3 pathway
LH Wei et al.
ONCOGENE (2003)
Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis
DY Wei et al.
ONCOGENE (2003)
STATs: Transcriptional control and biological impact
DE Levy et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
The BCL2 family: Regulators of the cellular life-or-death switch
S Cory et al.
NATURE REVIEWS CANCER (2002)
Coexpression of oncostatin M and its receptors and evidence for STAT3 activation in human ovarian carcinomas
TM Savarese et al.
CYTOKINE (2002)
Inhibition of constitutively active Stat3 suppresses growth of human ovarian and breast cancer cells
WM Burke et al.
ONCOGENE (2001)
Constitutive activation of Stat 3 oncogene product in human ovarian carcinoma cells
M Huang et al.
GYNECOLOGIC ONCOLOGY (2000)