期刊
BIOTECHNOLOGY ADVANCES
卷 33, 期 6, 页码 1327-1341出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.biotechadv.2015.03.014
关键词
Unimolecular micelles; Core-shell; Core-multishell; Hyperbranched; Dendritic; Polymeric amphiphiles; Encapsulation; Aggregation; Drug delivery; Targeting
资金
- U.S. National Science Foundation [CHE-0723497]
- Deutsche Forschungsgemeinschaft [DFG HA 2549/10-1]
Unimolecular micelles are covalently bound molecular architectures and therefore highly stable which makes them particularly attractive for drug delivery. Accordingly, many reports in the literature emphasize the importance of these molecular architectures for nanomedicine. This conceptual review will present some of the recent advances in the application of these dendritic core-shell systems for drug delivery. Unimolecular micelles based on hyperbranched and dendritic cores will be discussed and sorted by the nature of their core and structure. (C) 2015 Elsevier Inc. All rights reserved.
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