期刊
UNITED EUROPEAN GASTROENTEROLOGY JOURNAL
卷 8, 期 4, 页码 403-409出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/2050640620903225
关键词
Acute pancreatitis; amylase; revised Atlanta classification; Ringer's lactate solution; enteral nutrition; antibiotics
资金
- Instituto de Salud Carlos III
- Instituto de Investigacion Sanitaria (IIS) Aragon (Rio Hortega grant) [CM17/00145]
Acute pancreatitis is a heterogeneous illness. Most patients experience a mild course of disease, but one third will develop local complications and/or organ failure associated with increased morbidity and risk of mortality. Diagnosis of acute pancreatitis is based on typical epigastric pain, elevation of serum lipase or amylase levels, and/or characteristic findings on imaging. Personalised management is needed in patients with acute pancreatitis. Currently, analgesia, Ringer's lactate solution-based goal-directed fluid resuscitation and early oral refeeding providing enteral nutrition if not tolerated are the cornerstones for early management. Prophylactic antibiotics or endoscopic retrograde cholangiopancreatography in the absence of cholangitis are considered to be futile. Future clinical trials should address optimal fluid resuscitation, the early administration of anti-inflammatory drugs and the exact role of nutritional support in severe acute pancreatitis. Here, we present a patient case and review the diagnosis, treatment and prognosis of acute pancreatitis.
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