期刊
JOURNAL OF IMMUNOLOGY RESEARCH
卷 2020, 期 -, 页码 -出版社
HINDAWI LTD
DOI: 10.1155/2020/1704631
关键词
-
类别
资金
- National Natural Science Foundation of China [81800855]
- Hunan Province Natural Science Foundation [2018JJ3765]
- Changsha Science and Technology Project [kq1907075]
- Hunan Department of Science and Technology [2015TP2007]
Macrophages are involved in angiogenesis, an essential process for organ growth and tissue repair, and could contribute to the pathogenesis of angiogenesis-related diseases such as malignant tumors and diabetic retinopathy. Recently, long noncoding RNAs (lncRNAs) have been proved to be important in cell differentiation, organismal development, and various diseases of pathological angiogenesis. Moreover, it has been indicated that numerous lncRNAs exhibit different functions in macrophage infiltration and polarization and regulate the secretion of inflammatory cytokines released by macrophages. Therefore, the focus of macrophage-related lncRNAs could be considered to be a potential method in therapeutic targeting angiogenesis-related diseases. This review mainly summarizes the roles played by lncRNAs which associated with macrophages in angiogenesis. The possible mechanisms of the regulatory link between lncRNAs and macrophages in various angiogenesis-related diseases were also discussed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据