相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Structural Basis for Natural Product Selection and Export by Bacterial ABC Transporters
Maria Romano et al.
ACS CHEMICAL BIOLOGY (2018)
Order and disorder in the physiological membrane binding of alpha-synuclein
Giuliana Fusco et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2018)
C-terminal calcium binding of alpha-synuclein modulates synaptic vesicle interaction
Janin Lautenschlager et al.
NATURE COMMUNICATIONS (2018)
Lipid Extraction by α-Synuclein Generates Semi-Transmembrane Defects and Lipoprotein Nanoparticles
Jianjun Pan et al.
ACS OMEGA (2018)
α-Synuclein Regulates Neuronal Cholesterol Efflux
Jen-Hsiang T. Hsiao et al.
MOLECULES (2017)
Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers
Giuliana Fusco et al.
SCIENCE (2017)
Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stress
Stefanie Menges et al.
SCIENTIFIC REPORTS (2017)
Structural Ensembles of Membrane-bound α-Synuclein Reveal the Molecular Determinants of Synaptic Vesicle Affinity
Giuliana Fusco et al.
SCIENTIFIC REPORTS (2016)
Structure of the toxic core of α-synuclein from invisible crystals
Jose A. Rodriguez et al.
NATURE (2015)
Effects of impaired membrane interactions on α-synuclein aggregation and neurotoxicity
Daniel Ysselstein et al.
NEUROBIOLOGY OF DISEASE (2015)
The Synaptic Function of α-Synuclein
Jacqueline Burre
JOURNAL OF PARKINSONS DISEASE (2015)
Acceleration of α-Synuclein Aggregation by Exosomes
Marie Grey et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Protein/Lipid Coaggregates are Formed During a-Synuclein-Induced Disruption of Lipid Bilayers
Andreas van Maarschalkerweerd et al.
BIOMACROMOLECULES (2014)
The N-terminus of α-synuclein is essential for both monomeric and oligomeric interactions with membranes
Nikolai Lorenzen et al.
FEBS LETTERS (2014)
Synucleins Regulate the Kinetics of Synaptic Vesicle Endocytosis
Karina J. Vargas et al.
JOURNAL OF NEUROSCIENCE (2014)
Splice isoform and pharmacological studies reveal that sterol depletion relocalizes α-synuclein and enhances its toxicity
Julie S. Valastyan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
α-Synuclein assembles into higher-order multimers upon membrane binding to promote SNARE complex formation
Jacqueline Burre et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour
Giuliana Fusco et al.
NATURE COMMUNICATIONS (2014)
Small molecule-mediated stabilization of vesicle-associated helical α-synuclein inhibits pathogenic misfolding and aggregation
Luis Fonseca-Ornelas et al.
NATURE COMMUNICATIONS (2014)
Alpha-Synuclein Function and Dysfunction on Cellular Membranes
David Snead et al.
Experimental Neurobiology (2014)
G51D α-Synuclein mutation causes a novel Parkinsonian-pyramidal syndrome
Suzanne Lesage et al.
ANNALS OF NEUROLOGY (2013)
α-Synuclein Membrane Association Is Regulated by the Rab3a Recycling Machinery and Presynaptic Activity
Robert H. C. Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
α-Synuclein Senses Lipid Packing Defects and Induces Lateral Expansion of Lipids Leading to Membrane Remodeling
Myriam M. Ouberai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Solid-State 13C NMR Reveals Annealing of Raft-Like Membranes Containing Cholesterol by the Intrinsically Disordered Protein α-Synuclein
Avigdor Leftin et al.
JOURNAL OF MOLECULAR BIOLOGY (2013)
Insight into α-Synuclein Plasticity and Misfolding from Differential Micelle Binding
Parichita Mazumder et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2013)
Site-Specific Interaction between α-Synuclein and Membranes Probed by NMR-Observed Methionine Oxidation Rates
Alexander S. Maltsev et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
Alpha-synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease
Silke Appel-Cresswell et al.
MOVEMENT DISORDERS (2013)
The many faces of alpha-synuclein: from structure and toxicity to therapeutic target
Hilal A. Lashuel et al.
NATURE REVIEWS NEUROSCIENCE (2013)
Hydration dynamics as an intrinsic ruler for refining protein structure at lipid membrane interfaces
Chi-Yuan Cheng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2
Jiajie Diao et al.
ELIFE (2013)
Impact of N-Terminal Acetylation of α-Synuclein on Its Random Coil and Lipid Binding Properties
Alexander S. Maltsev et al.
BIOCHEMISTRY (2012)
Interaction of α-synuclein with vesicles that mimic mitochondrial membranes
Imola G. Zigoneanu et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2012)
Folding and misfolding of alpha-synuclein on membranes
Igor Dikiy et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2012)
1H, 13C and 15N resonance assignments of human muscle acylphosphatase
Giuliana Fusco et al.
BIOMOLECULAR NMR ASSIGNMENTS (2012)
Characterization of Semisynthetic and Naturally Nα-Acetylated α-Synuclein in Vitro and in Intact Cells IMPLICATIONS FOR AGGREGATION AND CELLULAR PROPERTIES OF α-SYNUCLEIN
Bruno Fauvet et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Studying Invisible Excited Protein States in Slow Exchange with a Major State Conformation
Pramodh Vallurupalli et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Structural Intermediates during α-Synuclein Fibrillogenesis on Phospholipid Vesicles
Gemma Comellas et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
Kelvin C. Luk et al.
SCIENCE (2012)
The fusogenic tilted peptide (67-78) of α-synuclein is a cholesterol binding domain
Jacques Fantini et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2011)
α-Synuclein Populates Both Elongated and Broken Helix States on Small Unilamellar Vesicles
Sowmya Bekshe Lokappa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Atomic-resolution dynamics on the surface of amyloid-β protofibrils probed by solution NMR
Nicolas L. Fawzi et al.
NATURE (2011)
In vivo demonstration that α-synuclein oligomers are toxic
Beate Winner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Membrane Interaction of alpha-Synuclein in Different Aggregation States
Marie Grey et al.
JOURNAL OF PARKINSONS DISEASE (2011)
Abnormal Neurites Containing C-Terminally Truncated α-Synuclein Are Present in Alzheimer's Disease without Conventional Lewy Body Pathology
Karen A. Lewis et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
alpha-Synuclein: Membrane Interactions and Toxicity in Parkinson's Disease
Pavan K. Auluck et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 26 (2010)
Differential Phospholipid Binding of α-Synuclein Variants Implicated in Parkinson's Disease Revealed by Solution NMR Spectroscopy
Christina R. Bodner et al.
BIOCHEMISTRY (2010)
Cholesterol involvement in the pathogenesis of neurodegenerative diseases
Jun-Ping Liu et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2010)
Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis
Venu M. Nemani et al.
NEURON (2010)
α-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
Jacqueline Burre et al.
SCIENCE (2010)
Biophysics of Parkinson's Disease: Structure and Aggregation of alpha-Synuclein
Vladimir N. Uversky et al.
CURRENT PROTEIN & PEPTIDE SCIENCE (2009)
Multiple Tight Phospholipid-Binding Modes of α-Synuclein Revealed by Solution NMR Spectroscopy
Christina R. Bodner et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
Analysis and optimization of saturation transfer difference NMR experiments designed to map early self-association events in amyloidogenic peptides
Hao Huang et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2008)
α-synuclein-induced aggregation of cytoplasmic vesicles in Saccharomyces cerevisiae
James H. Soper et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
Structure of membrane-bound α-synuclein from site-directed spin labeling and computational refinement
Christine C. Jao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The Parkinson's disease protein α-synuclein disrupts cellular Rab homeostasis
Aaron D. Gitler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Molecular anatomy of a trafficking organelle
Shigeo Takamori et al.
CELL (2006)
被撤回的出版物: Cytosolic proteins regulate α-synuclein dissociation from presynaptic membranes (Retracted article. See vol. 295, pg. 13694, 2020)
Sabine Wislet-Gendebien et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
α-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models
Antony A. Cooper et al.
SCIENCE (2006)
Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate α-synuclein fibrilization
DA Bosco et al.
NATURE CHEMICAL BIOLOGY (2006)
Comparison of structure and dynamics of micelle-bound human α-synuclein and Parkinson disease variants
TS Ulmer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Structure and dynamics of micelle-bound human α-synuclein
TS Ulmer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The new mutation, E46K, of α-synuclein causes Parkinson and Lewy body dementia
JJ Zarranz et al.
ANNALS OF NEUROLOGY (2004)
Rapid anionic micelle-mediated α-synuclein fibrillization in vitro
M Necula et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
α-synuclein locus triplication causes Parkinson's disease
AB Singleton et al.
SCIENCE (2003)
Lipid binding inhibits α-synuclein fibril formation
M Zhu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The formation of highly soluble oligomers of α-synuclein is regulated by fatty acids and enhanced in Parkinson's disease
R Sharon et al.
NEURON (2003)
Membrane-bound α-synuclein has a high aggregation propensity and the ability to seed the aggregation of the cytosolic form
HJ Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Exposure to long chain polyunsaturated fatty acids triggers rapid multimerization of synucleins
RJ Perrin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Conformational properties of α-synuclein in its free and lipid-associated states
D Eliezer et al.
JOURNAL OF MOLECULAR BIOLOGY (2001)