期刊
MICROMACHINES
卷 11, 期 2, 页码 -出版社
MDPI
DOI: 10.3390/mi11020176
关键词
liquid crystal biosensor; signal amplification technique; liquid crystal cell; virus; bacteria; protein; nucleic acid; small chemical molecules; metal ions
类别
资金
- National Natural Science Foundation of China [21175037]
- Guangdong Province Natural Science Foundation of China [2016A030313847]
Liquid crystal biosensors are based on changes in the orientation of liquid crystal molecules induced by specific bonding events of biomolecules. These biosensors are expected to serve as a promising system to detect biomolecules, biomolecular activity, and even small chemical molecules because they are inexpensive, sensitive, simple, effective, and portable. Herein, we introduce the principle and fabrication of liquid crystal biosensors and review the research progress in signal-amplified technology for liquid crystal sensing and its application in the detection of viruses, bacteria, proteins, nucleic acids, and small chemical molecules. In addition, the current theoretical and practical issues related to liquid crystal biosensors were investigated.
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