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Vaginal Myeloid Dendritic Cells Transmit Founder HIV-1
Ruizhong Shen et al.
JOURNAL OF VIROLOGY (2014)
Altered Viral Fitness and Drug Susceptibility in HIV-1 Carrying Mutations That Confer Resistance to Nonnucleoside Reverse Transcriptase and Integrase Strand Transfer Inhibitors
Zixin Hu et al.
JOURNAL OF VIROLOGY (2014)
Negative Elongation Factor Is Required for the Maintenance of Proviral Latency but Does Not Induce Promoter-Proximal Pausing of RNA Polymerase II on the HIV Long Terminal Repeat
Julie K. Jadlowsky et al.
MOLECULAR AND CELLULAR BIOLOGY (2014)
An HIV-Encoded Antisense Long noncoding RNA Epigenetically Regulates Viral Transcription
Sheena Saayman et al.
MOLECULAR THERAPY (2014)
HIV-1 persistence in CD4+ T cells with stem cell like properties
Maria J. Buzon et al.
NATURE MEDICINE (2014)
A cytoplasmic RNA virus generates functional viral small RNAs and regulates viral IRES activity in mammalian cells
Kuo-Feng Weng et al.
NUCLEIC ACIDS RESEARCH (2014)
HMGA1 recruits CTIP2-repressed P-TEFb to the HIV-1 and cellular target promoters
Sebastian Eilebrecht et al.
NUCLEIC ACIDS RESEARCH (2014)
CD4+ and CD8+ T Cell Activation Are Associated with HIV DNA in Resting CD4+ T Cells
Leslie R. Cockerham et al.
PLOS ONE (2014)
Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues
Courtney V. Fletcher et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Triptolide inhibits human immunodeficiency virus type 1 replication by promoting proteasomal degradation of Tat protein
Zhitao Wan et al.
RETROVIROLOGY (2014)
The lungs as anatomical reservoirs of HIV infection
Cecilia T. Costiniuk et al.
REVIEWS IN MEDICAL VIROLOGY (2014)
Epigenetic analysis of HIV-1 proviral genomes from infected individuals: Predominance of unmethylated CpG's
Stefanie Weber et al.
VIROLOGY (2014)
Activation of HIV Transcription with Short-Course Vorinostat in HIV-Infected Patients on Suppressive Antiretroviral Therapy
Julian H. Elliott et al.
PLOS PATHOGENS (2014)
Histone Deacetylase Inhibitors Impair the Elimination of HIV-Infected Cells by Cytotoxic T-Lymphocytes
Richard Brad Jones et al.
PLOS PATHOGENS (2014)
Dynamics of HIV Latency and Reactivation in a Primary CD4+T Cell Model
Pejman Mohammadi et al.
PLOS PATHOGENS (2014)
Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial
Thomas A. Rasmussen et al.
LANCET HIV (2014)
Entinostat is a histone deacetylase inhibitor selective for class 1 histone deacetylases and activates HIV production from latently infected primary T cells
Fiona Wightman et al.
AIDS (2013)
Disulfiram reactivates latent HIV-1 expression through depletion of the phosphatase and tensin homolog
Genevieve Doyon et al.
AIDS (2013)
Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure
Ya-Chi Ho et al.
CELL (2013)
Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production
Matthieu Perreau et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
The Distribution of HIV DNA and RNA in Cell Subsets Differs in Gut and Blood of HIV-Positive Patients on ART: Implications for Viral Persistence
Steven A. Yukl et al.
JOURNAL OF INFECTIOUS DISEASES (2013)
CD133+ Hematopoietic Progenitor Cells Harbor HIV Genomes in a Subset of Optimally Treated People With Long-Term Viral Suppression
Lucy A. McNamara et al.
JOURNAL OF INFECTIOUS DISEASES (2013)
Cyclin T1 and CDK9 T-Loop Phosphorylation Are Downregulated during Establishment of HIV-1 Latency in Primary Resting Memory CD4+ T Cells
Sona Budhiraja et al.
JOURNAL OF VIROLOGY (2013)
High Levels of CD2 Expression Identify HIV-1 Latently Infected Resting Memory CD4+ T Cells in Virally Suppressed Subjects
Maria Iglesias-Ussel et al.
JOURNAL OF VIROLOGY (2013)
HIV-1 Nef Sequence and Functional Compartmentalization in the Gut Is Not Due to Differential Cytotoxic T Lymphocyte Selective Pressure
Martha J. Lewis et al.
PLOS ONE (2013)
HIV DNA Reservoir Increases Risk for Cognitive Disorders in cART-Naive Patients
Victor G. Valcour et al.
PLOS ONE (2013)
CTIP2 is a negative regulator of P-TEFb
Thomas Cherrier et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Reactivation of latent HIV-1 in central memory CD4+ T cells through TLR-1/2 stimulation
Camille L. Novis et al.
RETROVIROLOGY (2013)
HIV-1 transcription and latency: an update
Carine Van Lint et al.
RETROVIROLOGY (2013)
HIV-1 pre-mRNA commitment to Rev mediated export through PSF and Matrin 3
Anna Kula et al.
VIROLOGY (2013)
Involvement of histone methyltransferase GLP in HIV-1 latency through catalysis of H3K9 dimethylation
Donglin Ding et al.
VIROLOGY (2013)
Comparison of HDAC inhibitors in clinical development Effect on HIV production in latently infected cells and T-cell activation
Thomas Aagaard Rasmussen et al.
HUMAN VACCINES & IMMUNOTHERAPEUTICS (2013)
An In-Depth Comparison of Latent HIV-1 Reactivation in Multiple Cell Model Systems and Resting CD4+T Cells from Aviremic Patients
Celsa A. Spina et al.
PLOS PATHOGENS (2013)
Promoter Targeting shRNA Suppresses HIV-1 Infection In vivo Through Transcriptional Gene Silencing
Kazuo Suzuki et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2013)
Histone methyltransferase inhibitors induce HIV-1 recovery in resting CD4+ T cells from HIV-1-infected HAART-treated patients
Sophie Bouchat et al.
AIDS (2012)
Redefining the Viral Reservoirs that Prevent HIV-1 Eradication
Evelyn Eisele et al.
IMMUNITY (2012)
Stimulation of HIV-1-Specific Cytolytic T Lymphocytes Facilitates Elimination of Latent Viral Reservoir after Virus Reactivation
Liang Shan et al.
IMMUNITY (2012)
Bromodomain and Extra-terminal (BET) Bromodomain Inhibition Activate Transcription via Transient Release of Positive Transcription Elongation Factor b (P-TEFb) from 7SK Small Nuclear Ribonucleoprotein
Koen Bartholomeeusen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Long-Term Nonprogressor and Elite Controller Patients Who Control Viremia Have a Higher Percentage of Methylation in Their HIV-1 Proviral Promoters than Aviremic Patients Receiving Highly Active Antiretroviral Therapy
Juan Antonio Palacios et al.
JOURNAL OF VIROLOGY (2012)
Paucity of HIV DNA Methylation in Latently Infected, Resting CD4+ T Cells from Infected Individuals Receiving Antiretroviral Therapy
Jana Blazkova et al.
JOURNAL OF VIROLOGY (2012)
Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy
N. M. Archin et al.
NATURE (2012)
Designed, synthetically accessible bryostatin analogues potently induce activation of latent HIV reservoirs in vitro
Brian A. DeChristopher et al.
NATURE CHEMISTRY (2012)
Directly Infected Resting CD4+T Cells Can Produce HIV Gag without Spreading Infection in a Model of HIV Latency
Matthew J. Pace et al.
PLOS PATHOGENS (2012)
Absence of HIV-1 Evolution in the Gut-Associated Lymphoid Tissue from Patients on Combination Antiviral Therapy Initiated during Primary Infection
Teresa H. Evering et al.
PLOS PATHOGENS (2012)
HIV latency: experimental systems and molecular models
Shweta Hakre et al.
FEMS MICROBIOLOGY REVIEWS (2012)
HIV envelope-mediated, CCR5/α4β7-dependent killing of CD4-negative γδ T cells which are lost during progression to AIDS
Haishan Li et al.
BLOOD (2011)
TLR8 Activates HIV from Latently Infected Cells of Myeloid-Monocytic Origin Directly via the MAPK Pathway and from Latently Infected CD4+ T Cells Indirectly via TNF-α
Erika Schlaepfer et al.
JOURNAL OF IMMUNOLOGY (2011)
Lack of Compartmentalization of HIV-1 Quasispecies Between the Gut and Peripheral Blood Compartments
Hiromi Imamichi et al.
JOURNAL OF INFECTIOUS DISEASES (2011)
Greater Diversity of HIV DNA Variants in the Rectum Compared to Variants in the Blood in Patients Without HAART
Veronique Avettand-Fenoel et al.
JOURNAL OF MEDICAL VIROLOGY (2011)
Negative Regulation of HIV-1 Transcription by a Heterodimeric NF-κB1/p50 and C-Terminally Truncated STAT5 Complex
Giulia Della Chiara et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
Epigenetic Silencing of HIV-1 by the Histone H3 Lysine 27 Methyltransferase Enhancer of Zeste 2
Julia Friedman et al.
JOURNAL OF VIROLOGY (2011)
Disulfiram Reactivates Latent HIV-1 in a Bcl-2-Transduced Primary CD4+ T Cell Model without Inducing Global T Cell Activation
Sifei Xing et al.
JOURNAL OF VIROLOGY (2011)
The Gut Mucosal Viral Reservoir in HIV-Infected Patients Is Not the Major Source of Rebound Plasma Viremia following Interruption of Highly Active Antiretroviral Therapy
Paula Lerner et al.
JOURNAL OF VIROLOGY (2011)
A human memory T cell subset with stem cell-like properties
Luca Gattinoni et al.
NATURE MEDICINE (2011)
In vivo, in vitro, and in silico analysis of methylation of the HIV-1 provirus
Leonard Chavez et al.
METHODS (2011)
Characterization of the HIV-1 RNA associated proteome identifies Matrin 3 as a nuclear cofactor of Rev function
Anna Kula et al.
RETROVIROLOGY (2011)
Deep Molecular Characterization of HIV-1 Dynamics under Suppressive HAART
Maria J. Buzon et al.
PLOS PATHOGENS (2011)
Discordance Between Cerebral Spinal Fluid and Plasma HIV Replication in Patients with Neurological Symptoms Who Are Receiving Suppressive Antiretroviral Therapy
Ana Canestri et al.
CLINICAL INFECTIOUS DISEASES (2010)
Involvement of Histone H3 Lysine 9 (H3K9) Methyltransferase G9a in the Maintenance of HIV-1 Latency and Its Reactivation by BIX01294
Kenichi Imai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Peripheral Blood CCR4+CCR6+ and CXCR3+CCR6+ CD4+ T Cells Are Highly Permissive to HIV-1 Infection
Annie Gosselin et al.
JOURNAL OF IMMUNOLOGY (2010)
Both CD31+ and CD31- Naive CD4+ T Cells Are Persistent HIV Type 1-Infected Reservoirs in Individuals Receiving Antiretroviral Therapy
Fiona Wightman et al.
JOURNAL OF INFECTIOUS DISEASES (2010)
HIV DNA in circulating monocytes as a mechanism to dementia and other HIV complications
Victor G. Valcour et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2010)
Compartmentalization and Clonal Amplification of HIV-1 Variants in the Cerebrospinal Fluid during Primary Infection
Gretja Schnell et al.
JOURNAL OF VIROLOGY (2010)
Molecular mechanisms of neuroinvasion by monocytes-macrophages in HIV-1 infection
Gabriel Gras et al.
RETROVIROLOGY (2010)
Expression of latent human immunodeficiency type 1 is induced by novel and selective histone deacetylase inhibitors
Nancie M. Archin et al.
AIDS (2009)
Persistent HIV RNA shedding in semen despite effective antiretroviral therapy
Prameet M. Sheth et al.
AIDS (2009)
Premature Aging of T cells Is Associated With Faster HIV-1 Disease Progression
Weiwei Cao et al.
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES (2009)
Characterization of Cdk9 T-loop phosphorylation in resting and activated CD4+ T lymphocytes
Rajesh Ramakrishnan et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2009)
HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
Nicolas Chomont et al.
NATURE MEDICINE (2009)
HIV DNA and cognition in a Thai longitudinal HAART initiation cohort The SEARCH 001 Cohort Study
V. G. Valcour et al.
NEUROLOGY (2009)
Synergistic Activation of HIV-1 Expression by Deacetylase Inhibitors and Prostratin: Implications for Treatment of Latent Infection
Sophie Reuse et al.
PLOS ONE (2009)
The integrin α4β7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1
Claudia Cicala et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Molecular control of HIV-1 postintegration latency: implications for the development of new therapeutic strategies
Laurence Colin et al.
RETROVIROLOGY (2009)
Control of Stochastic Gene Expression by Host Factors at the HIV Promoter
John C. Burnett et al.
PLOS PATHOGENS (2009)
miR-198 Inhibits HIV-1 Gene Expression and Replication in Monocytes and Its Mechanism of Action Appears To Involve Repression of Cyclin T1
Tzu-Ling Sung et al.
PLOS PATHOGENS (2009)
CpG Methylation Controls Reactivation of HIV from Latency
Jana Blazkova et al.
PLOS PATHOGENS (2009)
Epigenetic Regulation of HIV-1 Latency by Cytosine Methylation
Steven E. Kauder et al.
PLOS PATHOGENS (2009)
Detection of HIV-1 RNA in seminal plasma samples from treated patients with undetectable HIV-1 RNA in blood plasma
Anne-Genevieve Marcelin et al.
AIDS (2008)
Male genital tract compartmentalization of human immunodeficiency virus type 1 (HIV)
Kurt Diem et al.
AIDS RESEARCH AND HUMAN RETROVIRUSES (2008)
Orientation-dependent regulation of integrated HIV-1 expression by host gene transcriptional readthrough
Yefei Han et al.
CELL HOST & MICROBE (2008)
Transcriptional interference antagonizes proviral gene expression to promote HIV latency
Tina Lenasi et al.
CELL HOST & MICROBE (2008)
HIV-1 DNA load analysis in peripheral blood lymphocytes and monocytes from naive and HAART-treated individuals
Davide Gibellini et al.
JOURNAL OF INFECTION (2008)
Persistence of HIV in gut-associated lymphoid tissue despite long-term antiretroviral therapy
Tae-Wook Chun et al.
JOURNAL OF INFECTIOUS DISEASES (2008)
Resting Regulatory CD4 T Cells: A Site of HIV Persistence in Patients on Long-Term Effective Antiretroviral Therapy
Tu-Anh Tran et al.
PLOS ONE (2008)
Transcription regulation through promoter-proximal pausing of RNA polymerase II
Leighton J. Core et al.
SCIENCE (2008)
Comparison of HIV-1 pol and env sequences of blood, CSF, brain and spleen isolates collected ante-mortem and post-mortem
E. -C. Caragounis et al.
ACTA NEUROLOGICA SCANDINAVICA (2008)
CBF-1 promotes transcriptional silencing during the establishment of HIV-1 latency
Mudit Tyagi et al.
EMBO JOURNAL (2007)
HIV-1 infection of monocytes is directly related to the success of HAART
Sharilyn Almodovar et al.
VIROLOGY (2007)
c-Myc and sp1 contribute to proviral latency by recruiting histone deacetylase 1 to the human immunodeficiency virus type 1 promoter
Guochun Jiang et al.
JOURNAL OF VIROLOGY (2007)
Cellular microRNAs contribute to HIV-1 latency in resting primary CD4+ T lymphocytes
Jialing Huang et al.
NATURE MEDICINE (2007)
HMBA releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and activates HIV transcription
Xavier Contreras et al.
PLOS PATHOGENS (2007)
HIV-1 TAR element is processed by Dicer to yield a viral micro-RNA involved in chromatin remodeling of the viral LTR
Zachary Klase et al.
BMC MOLECULAR BIOLOGY (2007)
CTL fail to accumulate at sites of HIV-1 replication in lymphoid tissue
Elizabeth Connick et al.
JOURNAL OF IMMUNOLOGY (2007)
Suppression of microRNA-silencing pathway by HIV-1 during virus replication
Robinson Triboulet et al.
SCIENCE (2007)
Suv39H1 and HP1γ are responsible for chromatin-mediated HIV-1 transcriptional silencing and post-integration latency
Isaure du Chene et al.
EMBO JOURNAL (2007)
Recruitment of chromatin-modifying enzymes by CTIP2 promotes HIV-1 transcriptional silencing
Celine Marban et al.
EMBO JOURNAL (2007)
Convergence of TCR and cytokine signaling leads to FOXO3a phosphorylation and drives the survival of CD4+ central memory T cells
Catherine Riou et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Nuclear retention of multiply spliced HIV-1 RNA in resting CD4+ T cells
Kara G. Lassen et al.
PLOS PATHOGENS (2006)
Lower genitourinary tract sources of seminal HIV
RW Coombs et al.
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES (2006)
NF-κB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation
SA Williams et al.
EMBO JOURNAL (2006)
Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity
LS Weinberger et al.
CELL (2005)
Semen-specific genetic characteristics of human immunodeficiency virus type 1 env
SK Pillai et al.
JOURNAL OF VIROLOGY (2005)
Plasma and cerebrospinal fluid pharmacokinetics of depsipeptide (FR901228) in nonhuman primates
SL Berg et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2004)
Longitudinal and cross-sectional studies of HIV-1 RNA and DNA loads in blood and the female genital tract
AKN Iversen et al.
EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY (2004)
Resting CD4+ T cells from human immunodeficiency virus type I (HIV-1)-infected individuals carry integrated HIV-1 Genomes within actively transcribed host genes
YF Han et al.
JOURNAL OF VIROLOGY (2004)
Coaxing HIV-1 from resting CD4 T cells: histone deacetylase inhibition allows latent viral expression
L Ylisastigui et al.
AIDS (2004)
Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter
M Lusic et al.
EMBO JOURNAL (2003)
Recruitment of Tat to heterochromatin protein HP1 via interaction with CTIP2 inhibits human immunodeficiency virus type 1 replication in microglial cells
O Rohr et al.
JOURNAL OF VIROLOGY (2003)
Subcompartmentalization of HIV-1 quasispecies between seminal cells and seminal plasma indicates their origin in distinct genital tissues
S Paranjpe et al.
AIDS RESEARCH AND HUMAN RETROVIRUSES (2002)
Synergistic activation of human immunodeficiency virus type 1 promoter activity by NF-κB and inhibitors of deacetylases:: Potential perspectives for the development of therapeutic strategies
V Quivy et al.
JOURNAL OF VIROLOGY (2002)
HIV-1 integration in the human genome favors active genes and local hotspots
ARW Schröder et al.
CELL (2002)
The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription
ZY Yang et al.
NATURE (2001)
Prostratin: activation of latent HIV-1 expression suggests a potential inductive adjuvant therapy for HAART
J Kulkosky et al.
BLOOD (2001)
7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes
VT Nguyen et al.
NATURE (2001)
Decay kinetics of human immunodeficiency virus-specific CD8+ T cells in peripheral blood after initiation of highly active antiretroviral therapy
JP Casazza et al.
JOURNAL OF VIROLOGY (2001)
Nephropathy and establishment of a renal reservoir of HIV type 1 during primary infection
JA Winston et al.
NEW ENGLAND JOURNAL OF MEDICINE (2001)
Monocytes harbour replication-competent, non-latent HIV-1 in patients on highly active antiretroviral therapy
S Sonza et al.
AIDS (2001)
Persistence of infectious HIV on follicular dendritic cells
BA Smith et al.
JOURNAL OF IMMUNOLOGY (2001)
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