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Malaria antifolate resistance with contrasting Plasmodium falciparum dihydrofolate reductase (DHFR) polymorphisms in humans and Anopheles mosquitoes
Sungano Mharakurwa et al.
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Lipophilicity in drug discovery
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Lain D. Kerr et al.
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Discovery of novel inhibitors targeting enoyl-acyl carrier protein reductase in Plasmodium falciparum by structure-based virtual screening
George Nicola et al.
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P Kongsaeree et al.
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M Kapoor et al.
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J Raman et al.
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