相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。BCL-2 family isoforms in apoptosis and cancer
Chloe F. A. Warren et al.
CELL DEATH & DISEASE (2019)
Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens
Fiona M. Behan et al.
NATURE (2019)
A genome-wide positioning systems network algorithm for in silico drug repurposing
Feixiong Cheng et al.
NATURE COMMUNICATIONS (2019)
OrthoDB v10: sampling the diversity of animal, plant, fungal, protist, bacterial and viral genomes for evolutionary and functional annotations of orthologs
Evgenia V. Kriventseva et al.
NUCLEIC ACIDS RESEARCH (2019)
Personal Mutanomes Meet Modern Oncology Drug Discovery and Precision Health
Feixiong Cheng et al.
PHARMACOLOGICAL REVIEWS (2019)
A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples
Han Chen et al.
CELL (2018)
Comprehensive Characterization of Cancer Driver Genes and Mutations
Matthew H. Bailey et al.
CELL (2018)
Neutral Theory, Disease Mutations, and Personal Exomes
Sudhir Kumar et al.
MOLECULAR BIOLOGY AND EVOLUTION (2018)
Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas
Theo A. Knijnenburg et al.
CELL REPORTS (2018)
Impact of TP53 Mutations on Outcome in EGFR-Mutated Patients Treated with First-Line Tyrosine Kinase Inhibitors
Matteo Canale et al.
CLINICAL CANCER RESEARCH (2017)
The BET inhibitor JQ1 selectively impairs tumour response to hypoxia and downregulates CA9 and angiogenesis in triple negative breast cancer
L. L. da Motta et al.
ONCOGENE (2017)
KRAS, NRAS and BRAF mutations in colorectal cancer and melanoma
Jonas Cicenas et al.
MEDICAL ONCOLOGY (2017)
Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells
Robin M. Meyers et al.
NATURE GENETICS (2017)
Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions
John Paul Shen et al.
NATURE METHODS (2017)
2016 FDA drug approvals
Asher Mullard
NATURE REVIEWS DRUG DISCOVERY (2017)
Synthetic lethality and cancer
Nigel J. O'Neil et al.
NATURE REVIEWS GENETICS (2017)
Systematic discovery of mutation-specific synthetic lethals by mining pan-cancer human primary tumor data
Subarna Sinha et al.
NATURE COMMUNICATIONS (2017)
BET Bromodomain Inhibition Synergizes with PARP Inhibitor in Epithelial Ovarian Cancer
Sergey Karakashev et al.
CELL REPORTS (2017)
Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras
Tim Wang et al.
CELL (2017)
SynLethDB: synthetic lethality database toward discovery of selective and sensitive anticancer drug targets
Jing Guo et al.
NUCLEIC ACIDS RESEARCH (2016)
Ras Conformational Ensembles, Allostery, and Signaling
Shaoyong Lu et al.
CHEMICAL REVIEWS (2016)
A network-based drug repositioning infrastructure for precision cancer medicine through targeting significantly mutated genes in the human cancer genomes
Feixiong Cheng et al.
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION (2016)
A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer Therapy
Rohith Srivas et al.
MOLECULAR CELL (2016)
Synthetic lethal approaches for assessing combinatorial efficacy of chemotherapeutic drugs
Rebecca A. Jackson et al.
PHARMACOLOGY & THERAPEUTICS (2016)
A global genetic interaction network maps a wiring diagram of cellular function
Michael Costanzo et al.
SCIENCE (2016)
CRISPR Screens Provide a Comprehensive Assessment of Cancer Vulnerabilities but Generate False-Positive Hits for Highly Amplified Genomic Regions
Diana M. Munoz et al.
CANCER DISCOVERY (2016)
DNA repair, genome stability and cancer: a historical perspective
Penny A. Jeggo et al.
NATURE REVIEWS CANCER (2016)
Specific CDK4/6 inhibition in breast cancer: a systematic review of current clinical evidence
Anne Polk et al.
ESMO OPEN (2016)
Genomic Classification of Cutaneous Melanoma
Rehan Akbani et al.
CELL (2015)
FDA Approval: Idelalisib Monotherapy for the Treatment of Patients with Follicular Lymphoma and Small Lymphocytic Lymphoma
Barry W. Miller et al.
CLINICAL CANCER RESEARCH (2015)
Comparison of predicted and actual consequences of missense mutations
Lisa A. Miosge et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Somatic mutation in cancer and normal cells
Inigo Martincorena et al.
SCIENCE (2015)
A Gene Gravity Model for the Evolution of Cancer Genomes: A Study of 3,000 Cancer Genomes across 9 Cancer Types
Feixiong Cheng et al.
PLOS COMPUTATIONAL BIOLOGY (2015)
Predicting Cancer-Specific Vulnerability via Data-Driven Detection of Synthetic Lethality
Livnat Jerby-Arnon et al.
CELL (2014)
Studying Tumorigenesis through Network Evolution and Somatic Mutational Perturbations in the Cancer Interactome
Feixiong Cheng et al.
MOLECULAR BIOLOGY AND EVOLUTION (2014)
TCGA-Assembler: open-source software for retrieving and processing TCGA data
Yitan Zhu et al.
NATURE METHODS (2014)
Applying Synthetic Lethality for the Selective Targeting of Cancer
Donal P. McLornan et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Assessing PIK3CA and PTEN in Early-Phase Trials with PI3K/AKT/mTOR Inhibitors
Filip Janku et al.
CELL REPORTS (2014)
Targeting XRCC1 Deficiency in Breast Cancer for Personalized Therapy
Rebeka Sultana et al.
CANCER RESEARCH (2013)
Depletion of a Putatively Druggable Class of Phosphatidylinositol Kinases Inhibits Growth of p53-Null Tumors
Brooke M. Emerling et al.
CELL (2013)
Lessons from the Cancer Genome
Levi A. Garraway et al.
CELL (2013)
Chromatin and the genome integrity network
Manolis Papamichos-Chronakis et al.
NATURE REVIEWS GENETICS (2013)
A phase II study of afatinib (BIBW 2992), an irreversible ErbB family blocker, in patients with HER2-positive metastatic breast cancer progressing after trastuzumab
Nancy U. Lin et al.
BREAST CANCER RESEARCH AND TREATMENT (2012)
Collaboration of Kras and Androgen Receptor Signaling Stimulates EZH2 Expression and Tumor-Propagating Cells in Prostate Cancer
Houjian Cai et al.
CANCER RESEARCH (2012)
Mutual exclusivity analysis identifies oncogenic network modules
Giovanni Ciriello et al.
GENOME RESEARCH (2012)
BCL2L1 has a functional role in colorectal cancer and its protein expression is associated with chromosome 20q gain
Anke H. Sillars-Hardebol et al.
JOURNAL OF PATHOLOGY (2012)
BRCA1 and BRCA2 mutations correlate with TP53 abnormalities and presence of immune cell infiltrates in ovarian high-grade serous carcinoma
Jessica N. McAlpine et al.
MODERN PATHOLOGY (2012)
Comprehensive molecular portraits of human breast tumours
Daniel C. Koboldt et al.
NATURE (2012)
Antiangiogenic therapy: impact on invasion, disease progression, and metastasis
John M. L. Ebos et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2011)
COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer
Simon A. Forbes et al.
NUCLEIC ACIDS RESEARCH (2011)
Identification of H-Ras-Specific Motif for the Activation of Invasive Signaling Program in Human Breast Epithelial Cells
Hae-Young Yong et al.
NEOPLASIA (2011)
International network of cancer genome projects
Thomas J. Hudson et al.
NATURE (2010)
ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks
Gabriela Bindea et al.
BIOINFORMATICS (2009)
Breast cancer risk associated with BRCA1 and BRCA2 in diverse populations
James D. Fackenthal et al.
NATURE REVIEWS CANCER (2007)
Causes of oncogenic chromosomal translocation
PD Aplan
TRENDS IN GENETICS (2006)
Microarray analysis of bicalutamide action on telomerase activity, p53 pathway and viability of prostate carcinoma cell lines
J Bouchal et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2005)
Centrosome replication, genomic instability and cancer
A Krämer et al.
LEUKEMIA (2002)
Phosphorylation of centrin during the cell cycle and its role in centriole separation preceding centrosome duplication
W Lutz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Bcl-xL promotes metastasis of breast cancer cells by induction of cytokines resistance
Y Fernández et al.
CELL DEATH AND DIFFERENTIATION (2000)
分享论文
