相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。The Role of TGF-β and Its Receptors in Gastrointestinal Cancers
Jingwen Luo et al.
TRANSLATIONAL ONCOLOGY (2019)
NOTCH Signaling Is Activated through Mechanical Strain in Human Bone Marrow-Derived Mesenchymal Stromal Cells
Fani Ziouti et al.
STEM CELLS INTERNATIONAL (2019)
Optimizing sequential treatment with anti-EGFR and VEGF mAb in metastatic colorectal cancer: current results and controversies
Datian Chen et al.
CANCER MANAGEMENT AND RESEARCH (2019)
Celastrol inhibits colorectal cancer through TGF-β1/Smad signaling
Zhitao Jiang et al.
ONCOTARGETS AND THERAPY (2019)
The role of TGF-beta/SMAD4 signaling in cancer
Ming Zhao et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2018)
Colorectal Cancers: An Update on Their Molecular Pathology
Kentaro Inamura
CANCERS (2018)
Novel targeting approaches and signaling pathways of colorectal cancer: An insight
Ankita Tiwari et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2018)
Molecular characterization and biomarker identification in colorectal cancer: Toward realization of the precision medicine dream
Gaurav Goel
CANCER MANAGEMENT AND RESEARCH (2018)
Turning EGFR mutation-positive non-small-cell lung cancer into a chronic disease: optimal sequential therapy with EGFR tyrosine kinase inhibitors
Vera Hirsh
THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY (2018)
The MAPK-Signaling Pathway in Colorectal Cancer: Dysregulated Genes and Their Association With MicroRNAs
Martha L. Slattery et al.
CANCER INFORMATICS (2018)
Targeting the Raf kinases in human cancer: the Raf dimer dilemma
David E. Durrant et al.
BRITISH JOURNAL OF CANCER (2018)
Interaction between Wnt/beta-catenin and RAS-ERK pathways and an anti-cancer strategy via degradations of beta-catenin and RAS by targeting the Wnt/beta-catenin pathway
Woo-Jeong Jeong et al.
NPJ PRECISION ONCOLOGY (2018)
BRAF and NRAS Locus-Specific Variants Have Different Outcomes on Survival to Colorectal Cancer
Matthew G. Summers et al.
CLINICAL CANCER RESEARCH (2017)
Transforming Growth Factor β Superfamily Signaling in Development of Colorectal Cancer
Barbara Jung et al.
GASTROENTEROLOGY (2017)
Recent Advances in Targeting the EGFR Signaling Pathway for the Treatment of Metastatic Colorectal Cancer
Yuji Miyamoto et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
The interference of Notch1 target Hes1 affects cell growth, differentiation and invasiveness of glioblastoma stem cells through modulation of multiple oncogenic targets
Carlo Cenciarelli et al.
Oncotarget (2017)
DNA methylation epigenotype and clinical features of NRAS-mutation(+) colorectal cancer
Kiyoko Takane et al.
CANCER MEDICINE (2017)
TGFβ/Smad3 regulates proliferation and apoptosis through IRS-1 inhibition in colon cancer cells
Katie L. Bailey et al.
PLOS ONE (2017)
Activin signaling is an essential component of the TGF-β induced pro-metastatic phenotype in colorectal cancer
Jonas J. Staudacher et al.
SCIENTIFIC REPORTS (2017)
Association between mutations of critical pathway genes and survival outcomes according to the tumor location in colorectal cancer
Dae-Won Lee et al.
CANCER (2017)
Structure, signaling and the drug discovery of the Ras oncogene protein
Chang Woo Han et al.
BMB REPORTS (2017)
WNT Signaling and Colorectal Cancer
Emma M. Schatoff et al.
CURRENT COLORECTAL CANCER REPORTS (2017)
Targeting the Wnt signaling pathway in colorectal cancer
Masaaki Sawa et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2016)
The Notch pathway in colorectal cancer
Kaitlyn E. Vinson et al.
INTERNATIONAL JOURNAL OF CANCER (2016)
Proliferation, survival and metabolism: the role of PI3K/AKT/mTOR signalling in pluripotency and cell fate determination
Jason S. L. Yu et al.
DEVELOPMENT (2016)
Less frequently mutated genes in colorectal cancer: evidences from next-generation sequencing of 653 routine cases
Umberto Malapelle et al.
JOURNAL OF CLINICAL PATHOLOGY (2016)
Setting the Stage for Notch: The Drosophila Su(H)-Hairless Repressor Complex
Tilman Borggrefe et al.
PLOS BIOLOGY (2016)
Targeting Wnt signaling in colorectal cancer. A Review in the Theme: Cell Signaling: Proteins, Pathways and Mechanisms
Laura Novellasdemunt et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2015)
The role of the PI3K pathway in colorectal cancer
Dionysios Papadatos-Pastos et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2015)
Notch receptor regulation of intestinal stem cell homeostasis and crypt regeneration
Alexis J. Carulli et al.
DEVELOPMENTAL BIOLOGY (2015)
Polymerase Slippage Restoration of Frameshifted TGFBR2 in Colorectal Cancer: A Novel Paradigm
William M. Grady
GASTROENTEROLOGY (2015)
Epidermal growth factor receptor immunohistochemistry: new opportunities in metastatic colorectal cancer
Ryan A. Hutchinson et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2015)
A Tail of Two Sites: A Bipartite Mechanism for Recognition of Notch Ligands by Mind Bomb E3 Ligases
Brian J. McMillan et al.
MOLECULAR CELL (2015)
Molecular Pathways: Translational and Therapeutic Implications of the Notch Signaling Pathway in Cancer
Rebecca A. Previs et al.
CLINICAL CANCER RESEARCH (2015)
Epithelial-mesenchymal transition-associated microRNAs in colorectal cancer and drug-targeted therapies
Danjuan Jin et al.
ONCOLOGY REPORTS (2015)
Personalizing Therapy for Colorectal Cancer
Ashley Wong et al.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2014)
The PTEN/PI3K/Akt and Wnt/β-catenin signaling pathways are involved in the inhibitory effect of resveratrol on human colon cancer cell proliferation
Ying-Zi Liu et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2014)
The Notch ligand Jagged1 as a target for anti-tumor therapy
Demin Li et al.
FRONTIERS IN ONCOLOGY (2014)
Suppression of colon carcinogenesis by targeting Notch signaling
Shingo Miyamoto et al.
CARCINOGENESIS (2013)
Dysregulation and crosstalk of cellular signaling pathways in colon carcinogenesis
William K. K. Wu et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2013)
Targeting TGF-β signaling in cancer
Lior H. Katz et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2013)
Notch1-dependent regulation of p27 determines cell fate in colorectal cancer
Nevyana R. Hristova et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2013)
In vivo and in vitro models for the therapeutic targeting of Wnt signaling using a Tet-OΔN89β-catenin system
T. Jarde et al.
ONCOGENE (2013)
Notch3 Overexpression as Potential Therapeutic Target in Advanced Stage Chemoresistant Ovarian Cancer
Mohammed Tanjimur Rahman et al.
AMERICAN JOURNAL OF CLINICAL PATHOLOGY (2012)
Wnt/β-Catenin Signaling and Disease
Hans Clevers et al.
CELL (2012)
Developmental pathways in colon cancer Crosstalk between WNT, BMP, Hedgehog and Notch
Fred E. Bertrand et al.
CELL CYCLE (2012)
Comprehensive molecular characterization of human colon and rectal cancer
Donna M. Muzny et al.
NATURE (2012)
The complex world of WNT receptor signalling
Christof Niehrs
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Wnt Signaling in Cancer
Paul Polakis
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)
Debate about TGFBR1 and the susceptibility to colorectal cancer
Laura Valle
WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY (2012)
Molecular Genetics of Colorectal Cancer
Eric R. Fearon
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 6 (2011)
TGFβ (transforming growth factor β) receptor type III directs clathrin-mediated endocytosis of TGFβ receptor types I and II
Sarah McLean et al.
BIOCHEMICAL JOURNAL (2010)
Inhibition of phosphatidylinositol 3-kinase promotes tumor cell resistance to chemotherapeutic agents via a mechanism involving delay in cell cycle progression
Gail T. McDonald et al.
EXPERIMENTAL CELL RESEARCH (2010)
Inhibition of Aldose Reductase Prevents Growth Factor-Induced G1-S Phase Transition through the AKT/Phosphoinositide 3-Kinase/E2F-1 Pathway in Human Colon Cancer Cells
Kota V. Ramana et al.
MOLECULAR CANCER THERAPEUTICS (2010)
γ-Secretase Inhibitors Abrogate Oxaliplatin-Induced Activation of the Notch-1 Signaling Pathway in Colon Cancer Cells Resulting in Enhanced Chemosensitivity
Raymond D. Meng et al.
CANCER RESEARCH (2009)
Role of Notch signaling in colorectal cancer
Liang Qiao et al.
CARCINOGENESIS (2009)
TGF-β signaling alterations and susceptibility to colorectal cancer
Yanfei Xu et al.
HUMAN MOLECULAR GENETICS (2007)
The MAPK signalling pathways and colorectal cancer
JY Fang et al.
LANCET ONCOLOGY (2005)