相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Molecular interaction studies of Deguelin and its derivatives with Cyclin D1 and Cyclin E in cancer cell signaling pathway: The computational approach
Kiran Bharat Lokhande et al.
SCIENTIFIC REPORTS (2019)
Design, synthesis, biological evaluation, and molecular dynamics of novel cholinesterase inhibitors as anti-Alzheimer's agents
Reza Shamsimeymandi et al.
ARCHIV DER PHARMAZIE (2019)
Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase
Ehab D. AlFadly et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Strategy and validation of a structure-based method for the discovery of selective inhibitors of PAK isoforms and the evaluation of their anti-cancer activity
Pei-Lu Song et al.
BIOORGANIC CHEMISTRY (2019)
Synthesis, biological evaluation, and computational studies of novel fused six-membered O-containing heterocycles as potential acetylcholinesterase inhibitors
Yaghoub Pourshojaei et al.
COMPUTATIONAL BIOLOGY AND CHEMISTRY (2019)
Benzoic acid-derived nitrones: A new class of potential acetylcholinesterase inhibitors and neuroprotective agents
Catarina Oliveira et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
A short perspective on the long road to effective treatments for Alzheimer's disease
David S. Reynolds
BRITISH JOURNAL OF PHARMACOLOGY (2019)
Efficient, straightforward, catalyst-free synthesis of medicinally important S-alkyl/benzyl dithiocarbamates under green conditions
Ali Asadipour et al.
RESEARCH ON CHEMICAL INTERMEDIATES (2018)
RNA Structural Dynamics As Captured by Molecular Simulations: A Comprehensive Overview
Jiri Sponer et al.
CHEMICAL REVIEWS (2018)
Ultrasound-assisted and Efficient Knoevenagel Condensation Reaction Catalyzed by Silica Sodium Carbonate Nanoparticles
Yaghoub Pourshojaei et al.
CROATICA CHEMICA ACTA (2018)
Synthesis, pharmacology and molecular docking on multifunctional tacrine-ferulic acid hybrids as cholinesterase inhibitors against Alzheimer's disease
Jie Zhu et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2018)
An eco-friendly synthesis of 4-aryl-substituted pyrano-fuzed coumarins as potential pharmacological active heterocycles using molybdenum oxide nanoparticles as an effective and recyclable catalyst
Yaghoub Pourshojaei et al.
RESEARCH ON CHEMICAL INTERMEDIATES (2018)
Donepezil-based multi-functional cholinesterase inhibitors for treatment of Alzheimer's disease
Qi Li et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
Novel 2-pheynlbenzofuran derivatives as selective butyrylcholinesterase inhibitors for Alzheimer's disease
Amit Kumar et al.
SCIENTIFIC REPORTS (2018)
Identification of novel acetylcholinesterase inhibitors designed by pharmacophore-based virtual screening, molecular docking and bioassay
Cheongyun Jang et al.
SCIENTIFIC REPORTS (2018)
Isosteroidal alkaloids as potent dual-binding site inhibitors of both acetylcholinesterase and butyrylcholinesterase from the bulbs of Fritillaria walujewii
Yu-Ming Liu et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
From dual binding site acetylcholinesterase inhibitors to allosteric modulators: A new avenue for disease-modifying drugs in Alzheimer's disease
Talita P. C. Chierrito et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
Design, synthesis, molecular modeling and anticholinesterase activity of benzylidene-benzofuran-3-ones containing cyclic amine side chain
Farzad Mehrabi et al.
FUTURE MEDICINAL CHEMISTRY (2017)
Phantom PAINS: Problems with the Utility of Alerts for Pan-Assay INterference CompoundS
Stephen J. Capuzzi et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2017)
Novel multitarget-directed tacrine derivatives as potential candidates for the treatment of Alzheimer's disease
Wen-Yu Wu et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2017)
Recent developments in structural studies on acetylcholinesterase
Israel Silman et al.
JOURNAL OF NEUROCHEMISTRY (2017)
Comparison of the Binding of Reversible Inhibitors to Human Butyrylcholinesterase and Acetylcholinesterase: A Crystallographic, Kinetic and Calorimetric Study
Terrone L. Rosenberry et al.
MOLECULES (2017)
Evaluation of Novel Dual Acetyl- and Butyrylcholinesterase Inhibitors as Potential Anti-Alzheimer's Disease Agents Using Pharmacophore, 3D-QSAR and Molecular Docking Approaches
Xiaocong Pang et al.
MOLECULES (2017)
Why is Aged Acetylcholinesterase So Difficult to Reactivate?
Daniel M. Quinn et al.
MOLECULES (2017)
A short synthesis of 7-amino alkoxy homoisoflavonoides
Ali Asadipour et al.
RSC ADVANCES (2017)
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
Antoine Daina et al.
SCIENTIFIC REPORTS (2017)
Synthesis and screening of triazolopyrimidine scaffold as multi-functional agents for Alzheimer's disease therapies
Jitendra Kumar et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)
Silica sodium carbonate catalyzed in water synthesis of novel benzylbarbiturocoumarin derivatives
Khalil Eskandari et al.
TETRAHEDRON LETTERS (2016)
Principles and Overview of Sampling Methods for Modeling Macromolecular Structure and Dynamics
Tatiana Maximova et al.
PLOS COMPUTATIONAL BIOLOGY (2016)
Design, synthesis and anticholinesterase activity of novel benzylidenechroman-4-ones bearing cyclic amine side chain
Yaghoub Pourshojaei et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2015)
Efficacy and Safety of Donepezil, Galantamine, Rivastigmine, and Memantine for the Treatment of Alzheimer's Disease: A Systematic Review and Meta-Analysis
Chen-Chen Tan et al.
JOURNAL OF ALZHEIMERS DISEASE (2014)
Inhibition of acetylcholinesterase by two genistein derivatives: kinetic analysis, molecular docking and molecular dynamics simulation
Jiansong Fang et al.
ACTA PHARMACEUTICA SINICA B (2014)
Acetylcholinesterase Inhibitors: Pharmacology and Toxicology
Mirjana B. Colovic et al.
CURRENT NEUROPHARMACOLOGY (2013)
Design, synthesis, biological evaluation and docking study of 5-oxo-4,5-dihydropyrano[3,2-c]chromene derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors
Mehdi Khoobi et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2013)
Design, synthesis, and evaluation of indanone derivatives as acetylcholinesterase inhibitors and metal-chelating agents
Fan-Chao Meng et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Pyridonepezils, new dual AChE inhibitors as potential drugs for the treatment of Alzheimer's disease: Synthesis, biological assessment, and molecular modeling
Abdelouahid Samadi et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2012)
admetSAR: A Comprehensive Source and Free Tool for Assessment of Chemical ADMET Properties
Feixiong Cheng et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2012)
Structures of Human Acetylcholinesterase in Complex with Pharmacologically Important Ligands
Jonah Cheung et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Mouse Acetylcholinesterase Enhances Neurite Outgrowth of Rat R28 Cells Through Interaction With Laminin-1
Laura E. Sperling et al.
PLOS ONE (2012)
SHAKE parallelization
R. Elber et al.
EUROPEAN PHYSICAL JOURNAL-SPECIAL TOPICS (2011)
Interactions of AChE with A beta aggregates in Alzheimer's brain: therapeutic relevance of IDN 5706
Francisco J. Carvajal et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2011)
Acetylcholinesterase: From 3D structure to function
Hay Dvir et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2010)
Emerging hypotheses regarding the influences of butyrylcholinesterase-K variant, APOE ε4, and hyperhomocysteinemia in neurodegenerative dementias
Roger M. Lane et al.
MEDICAL HYPOTHESES (2009)
Dynamics of the acetylcholinesterase tetramer
Alemayehu A. Gorfe et al.
BIOPHYSICAL JOURNAL (2008)
Lessons learnt from assembling screening libraries for drug discovery for neglected diseases
Ruth Brenk et al.
CHEMMEDCHEM (2008)
Acetylcholinesterase in cell adhesion, neurite growth and network formation
Laura E. Paraoanu et al.
FEBS JOURNAL (2008)
The GSK3 hypothesis of Alzheimer's disease
Claudie Hooper et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Extra precision glide: Docking and scoring incorporating a model of hydrophobic enclosure for protein-ligand complexes
Richard A. Friesner et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
Targeting acetylcholinesterase and butyrylcholinesterase in dementia
RM Lane et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2006)
Glide: A new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy
RA Friesner et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
Glide: A new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screening
TA Halgren et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
Crystal structure of human butyrylcholinesterase and of its complexes with substrate and products
Y Nicolet et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
β-amyloid aggregation induced by human acetylcholinesterase:: inhibition studies
M Bartolini et al.
BIOCHEMICAL PHARMACOLOGY (2003)
High activity of human butyrylcholinesterase at low pH in the presence of excess butyrylthiocholine
P Masson et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2003)