期刊
NUTRIENTS
卷 12, 期 1, 页码 -出版社
MDPI
DOI: 10.3390/nu12010058
关键词
insulin resistance; diabetes; curcumin; curcuminoids; in vivo; animal studies; human studies
资金
- Natural Sciences and Engineering Research Council of Canada (NSERC)
Type 2 diabetes mellitus (T2DM) is a growing metabolic disease characterized by insulin resistance and hyperglycemia. Current preventative and treatment approaches to insulin resistance and T2DM lack in efficacy, resulting in the need for new approaches to prevent and treat the disease. In recent years, epidemiological studies have suggested that diets rich in fruits and vegetables have beneficial health effects, including protection against insulin resistance and T2DM. Curcumin, a polyphenol found in turmeric, and curcuminoids have been reported to have antioxidant, anti-inflammatory, hepatoprotective, nephroprotective, neuroprotective, immunomodulatory and antidiabetic properties. The current review (II of II) summarizes the existing in vivo studies examining the antidiabetic effects of curcumin.
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