4.4 Article

Dynamics analysis of a delayed virus model with two different transmission methods and treatments

期刊

ADVANCES IN DIFFERENCE EQUATIONS
卷 2020, 期 1, 页码 -

出版社

SPRINGEROPEN
DOI: 10.1186/s13662-019-2438-0

关键词

Cell-to-cell transmission; Delayed virus model; Treatment; Hopf bifurcation

资金

  1. National Natural Science Foundation of China [11801014, 11875001]
  2. Natural Science Foundation of Hebei Province [A2018409004]
  3. Hebei province university discipline top talent selection and training program [SLRC2019020]
  4. Talent Training Project of Hebei Province

向作者/读者索取更多资源

In this paper, a delayed virus model with two different transmission methods and treatments is investigated. This model is a time-delayed version of the model in (Zhang et al. in Comput. Math. Methods Med. 2015:758362, 2015). We show that the virus-free equilibrium is locally asymptotically stable if the basic reproduction number is smaller than one, and by regarding the time delay as a bifurcation parameter, the existence of local Hopf bifurcation is investigated. The results show that time delay can change the stability of the endemic equilibrium. Finally, we give some numerical simulations to illustrate the theoretical findings.

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