期刊
JOURNAL OF FUNCTIONAL FOODS
卷 65, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.jff.2019.103744
关键词
Lactic acid bacteria; Fermented goat milk; Gut microbiota; 16S rRNA gene sequencing
资金
- Shaanxi Provincial Science and Technology Department [2018ZDXM-NY-094]
- Xi'an Science and Technology Bureau [20193038YF026NS026]
The impact of fermented cow milk on gut microbiota has been extensively studied, however, the role of fermented goat milk (FGM) has not been well evaluated. The present study using 16S rRNA gene sequencing technology investigated the effect of FGM intake on small intestinal microbiota in mice. It was found that FGM intake decreased microbial diversity and significantly altered microbiota composition, particularly the genera Lactobacillus and Streptococcus. Moreover, metabolism and disease profiles were shifted by the FGM based on the function prediction. The expression of immune factors including tumor necrosis factor alpha (Tnf alpha), granzyme B (Gzmb), perforin (Prf) and aryl hydrocarbon receptor (Ahr) was also regulated by FGM treatment. Collectively, our findings reveal that FGM intake can exert beneficial effects on small intestinal microbiota and further modulate the host metabolism and immune responses. Therefore, the FGM can serve as an alternative functional food to improve health through gut bacterial management.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据