期刊
TRENDS IN IMMUNOLOGY
卷 40, 期 12, 页码 1105-1119出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.it.2019.10.001
关键词
-
类别
资金
- Spinoza Grant of The Netherlands Organization for Scientific Research
- ERC Advanced Grant [833247]
- European Research Council (ERC) [833247] Funding Source: European Research Council (ERC)
The evolution of mankind has constantly been influenced by the pathogens encountered. The various populations of modern humans that ventured out of Africa adapted to different environments and faced a large variety of infectious agents, resulting in local adaptations of the immune system for these populations. The functional variation of immune genes as a result of evolution is relevant in the responses against infection, as well as in the emergence of autoimmune and inflammatory diseases observed in modern populations. Understanding how host-pathogen interactions have influenced the human immune system from an evolutionary perspective might contribute to unveiling the causes behind different immune-mediated disorders and promote the development of new strategies to detect and control such diseases.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据