期刊
TETRAHEDRON LETTERS
卷 61, 期 1, 页码 -出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2019.151359
关键词
Naphthoxanthenones; Phenylphenalenones; Cyclocondensation
资金
- Universidad de Antioquia [CODI 2017-16205]
5-methoxy-1H-naphtho[2,1,8-mna]xanthen-1-one (1) and 5-methoxy-3H-naphtho[2,1,8-mna]xanthen-3-one (musafluorone 2), a pair of positional isomers isolated from Wachendorfia thyrsiflora and Musa acuminata, were synthesized in six steps in an overall yield of 53% and 59% starting from the corresponding methoxyphenalenones and employing an acid mediated cyclocondensation strategy. Preliminary assays demonstrated the intercalation ability of compounds 1 and 2 into DNA. (C) 2019 Elsevier Ltd. All rights reserved.
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