Recent Developments in Highly Stereoselective Michael Addition Reactions Catalyzed by Metal Complexes

Achieving high enantioselectivity and diastereoselectivity simultaneously- is a rather challenging task for asymmetric catalytic synthesis-. Thanks to the rapid development of asymmetric transition-metal catalysis, significant progress has been made during recent years in achieving highly enantio- and diastereoselective conjugate addition reactions with a diverse combination of Michael donors and acceptors. This short review surveys the advances in transition-metal-catalyzed asymmetric diastereoselective Michael addition including diastereodivergent catalysis developed between 2015 and 2019. The review is divided into multiple parts according to the type of nucleophiles involved in the reaction.