期刊
SYNTHESIS-STUTTGART
卷 52, 期 8, 页码 1279-1286出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0039-1691589
关键词
acylation; radical reactions; sulfoximines; N; -bromosuccinimide; microwave irradiation
资金
- South African National Research Foundation [105213, 105236]
- Aspen Pharmacare
- South African Medical Research Council
An efficient catalyst-free radical cross-coupling reaction between aromatic aldehydes and sulfoximines was developed. The reaction took place in the presence of N -bromosuccinimide as the radical initiator under microwave irradiation to afford the corresponding acylated sulfoximines in moderate to excellent yields (27 examples). This protocol proved to be rapid, easy to handle, and applicable to a broad scope of substrates.
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