Non-enzymatic salivary glucose detection using porous CuO nanostructures

Porous CuO electrodes have been fabricated using a low cost hydrothermal synthesis. Enzyme-less glucose detection ability of such porous electrodes has been optimized for different growth conditions. The maximum sensitivity of the electrode has been found to be similar to 3072 mu AmM-1 cm(-2), in the linear detection range of 5 mu M to 0.225 mM and detection limit of similar to 0.41 mu M. Such CuO based porous electrodes showed ultrafast response time (similar to 0.8 s) and excellent sensitivity towards glucose detection. The glucose sensing experiments in human saliva samples using porous CuO electrodes have been demonstrated in this study. A high sensitivity of similar to 2299 mu AmM-1 cm(-2) was obtained, for glucose sensing in human saliva samples. This study shows the potential application of porous CuO as electrode materials for cost effective, enzyme-less and non-invasive glucose sensors for bio-medical devices.