期刊
SENSORS AND ACTUATORS B-CHEMICAL
卷 303, 期 -, 页码 -出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.snb.2019.127216
关键词
Ratiometric; Fluorescent; Sensor; Cd2+; Detection; Bio-imaging
资金
- National Natural Science Foundation of China [21475080]
- Shanxi Scholarship Council of China [2017-Key 1]
- Shanxi Province Hundred Talents Project
- Application and Fundamental Research Project of Shanxi Province [201801D121236]
A very simple schiff base fluorescent probe (NIS) was facilely prepared via a one-step, one-pot condensation reaction between 2, 3-naphthalenediamine and imidazole-2-carboxaldehyde. Among common biologically relevant metal ions, NIS can selectively recognize Cd2+ via ratiometric fluorescence signal. The chelation of NIS with the Cd2+ ions resulted in a fluorescence enhancement together with a blue shift (74 nm) in the emission maxima, presumably due to the combined effects of ICT (internal charge transfer) and CHEF (chelation-enhanced fluorescence). The binding stoichiometry of NIS to Cd2+ is 1:1 and the fluorescence intensity ratio (F398/F472) changes allow a ratiometric detection of Cd2+ with the detection limit of 3.87 x 10(-7) M. Under fluorescence confocal microscope and via two emission channels, the probe is capable to detect Cd2+ ions in Human liver cancer cells (SMMC-7721), zebrafish and live tissues of Arabidopsis thaliana, demonstrating its applicability for detecting Cd2+ ions in different biological context with low toxicity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据