期刊
PLASMA PROCESSES AND POLYMERS
卷 17, 期 10, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ppap.201900269
关键词
airborne; dielectric barrier discharge; inactivation; porcine reproductive and respiratory syndrome; reactive species
资金
- University of Minnesota
- National Science Foundation [PHY 1903151]
- Kermit and Ione Ebeltoft Interdisciplinary Doctoral Fellowship
The transmission of airborne diseases in animals poses great risks to animal safety with potential significant economic losses. In this study, we report on the use of a dielectric barrier discharge (DBD) for in-flight inactivation of an airborne aerosolized porcine reproductive and respiratory syndrome virus. The infectivity of the sampled virus downstream compared to upstream of the DBD reactor as determined by the TCID50 method showed a similar to 3.5 log(10) reduction in the virus titer. Independent testing of the viral genome by the reverse-transcription quantitative real-time polymerase chain reaction method confirmed the inactivation with minimal filtering effects. Both short-lived species such as OH center dot and O2(a1 Delta g) and peroxynitrous acid (ONOOH) chemistry at low pH in the virus-laden droplets are suggested to be responsible for the observed inactivation.
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