期刊
PHARMACOLOGICAL RESEARCH
卷 150, 期 -, 页码 -出版社
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.phrs.2019.104501
关键词
ALD; Natural products; Extracts; Formulations
资金
- National Natural Science Foundation of China [81700522, 81602344]
- Natural Science Foundation of Anhui Province [1808085MH235]
- Grants for Scientific Research of BSKY of Anhui Medical University [XJ201624]
- Natural Science Foundation of Colleges and Universities in Anhui Province [KJ2018A0845]
Alcoholic liver disease (ALD) is a major cause of chronic liver disease worldwide that afflicts human health. With the in-depth study of the disease, its pathogenesis has gradually become clear. Although great breakthroughs have been made in the research of ALD, the research and development of drugs related to ALD has lagged behind seriously. However, natural products have always inspired the development of drugs. Meanwhile, there is evidence that some natural products can also play a certain role in the treatment of ALD. Thus, we reviewed the natural products, extracts and formulations with potential anti-ALD activities by consulting the relevant data in the databases of PubMed, Web of Science and CNKI databases, in order to elucidate the regulated mechanism of these natural products. Sum up, the insights provided in present review will be needed for further exploration of botanical drugs in the development of ALD therapy.
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