4.2 Article

Lipoprotein(a) as a marker for predicting coronary collateral circulation in patients with acute myocardial infarction

期刊

PERSONALIZED MEDICINE
卷 17, 期 1, 页码 67-78

出版社

FUTURE MEDICINE LTD
DOI: 10.2217/pme-2018-0127

关键词

acute myocardial infarction; collateral circulation; coronary artery; Lipoprotein(a); marker; prediction

资金

  1. Capital Health Development Fund [201614035]
  2. CAMSMajor Collaborative Innovation Project [2016-I2M-1-011]

向作者/读者索取更多资源

Aim: The aim of the present study was to examine the predictive value of lipoprotein(a) (Lp[a]) levels for coronary collateral circulation (CCC) in patients with acute myocardial infarction (AMI). Method & methods: A total of 409 consecutive patients with AMI were enrolled for this study. Patients were divided into two groups according to rentrop grades assessed by coronary angiography: bad (n = 277) and good CCC group (n = 132). Result: Patients with bad CCC had a higher level of Lp(a) than that with good CCC (median Lp[a] 219.1 vs 122.0 mg/l). The area under the receiver-operating characteristic curves of Lp(a) in predicting bad CCC was 0.647 (95% CI: 0.592-0.702) with the cut-off value of 199.0 mg/l. Conclusion: Our data firstly suggested that Lp(a) might be a useful marker for CCC after AMI.

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