期刊
ORGANIC LETTERS
卷 22, 期 2, 页码 391-394出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.9b04054
关键词
-
资金
- National Natural Science Foundation of China [21871160, 21672121]
- Thousand Plan Youth Program of China
A chiral carbene-catalyzed [3+3] annulation of alpha-bromoenals with 2-aminobenzimidazoles providing pyrimido[1,2-a]benzimidazoles has been described. This protocol features a broad scope and good functional group tolerance. Biological studies indicated that the formed pyrimido[1,2-a]benzimidazole exhibited moderate cytotoxic activity against tumor cells.
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