期刊
OPTICS EXPRESS
卷 28, 期 6, 页码 9002-9013出版社
OPTICAL SOC AMER
DOI: 10.1364/OE.389714
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资金
- National Natural Science Foundation of China [61775028, 81571722]
- Southern University of Science and Technology
In this study, we evaluate the penetration capability of light in visible, near-infrared-I (NIR-1) and near-infrared-II (NIR-II) optical windows for photoacoustic macroscale imaging inside 9 biological tissues with three typical penetration depths. An acoustic resolution photoacoustic microscopy is designed to guarantee the consistent experiment conditions except excitation wavelength. Experimental results show that short NIR-II (1000-1150 nm) shows the best performance inside kidney, spleen and liver tissues at all depths, while NIR-I (700-1000 nm) works better for muscle, stomach, heart and brain tissues, especially in deep imaging. This study proposes the optimal selection of illumination wavelengths for photoacoustic macroscale imaging in rat organs, which enables the best signal-to-noise ratio (SNR) of the observed target. (C) 2020 Optical Society of America under the terms of the OSA Open Access Publishing Agreement
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