Imaging of Posttraumatic Stress Disorder

This review summarizes current knowledge obtained from psychoradiological studies of posttraumatic stress disorder (PTSD). The authors first focus on 3 key anatomic structures (hippocampus, amygdala, and medial prefrontal cortex) and the functional circuits to which they contribute. In addition, they discuss the triple-network model, a widely accepted neurobiological model of PTSD that explains the vast majority of neuroimaging findings, as well as their interactions and relationships to functional disruptions in PTSD.