相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Cytoplasmic functions of TDP-43 and FUS and their role in ALS
Nicol Birsa et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2020)
Nucleocytoplasmic transport defects in neurodegeneration - Cause or consequence?
Saskia Hutten et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2020)
The molecular language of membraneless organelles
Edward Gomes et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
The Structure of the Nuclear Pore Complex (An Update)
Daniel H. Lin et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 88 (2019)
RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43
Jacob R. Mann et al.
NEURON (2019)
Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death
Fatima Gasset-Rosa et al.
NEURON (2019)
Molecular Mechanisms of TDP-43 Misfolding and Pathology in Amyotrophic Lateral Sclerosis
Archana Prasad et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2019)
Heterogeneous nuclear ribonucleoproteins R and Q accumulate in pathological inclusions in FTLD-FUS
Lauren M. Gittings et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2019)
ADAR2 mislocalization and widespread RNA editing aberrations in C9orf72-mediated ALS/FTD
Stephen Moore et al.
ACTA NEUROPATHOLOGICA (2019)
Motor neurons from ALS patients with mutations in C9ORF72 and SOD1 exhibit distinct transcriptional landscapes
Ching-On Wong et al.
HUMAN MOLECULAR GENETICS (2019)
Genetics of amyotrophic lateral sclerosis: A review
Stephane Mathis et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2019)
Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis
Giulia E. Tyzack et al.
BRAIN (2019)
A unified mechanism for LLPS of ALS/FTLD-causing FUS as well as its modulation by ATP and oligonucleic acids
Jian Kang et al.
PLOS BIOLOGY (2019)
The Role of TDP-43 in Military-Relevant TBI and Chronic Neurodegeneration
Lanier Heyburn et al.
FRONTIERS IN NEUROLOGY (2019)
The basis of clinicopathological heterogeneity in TDP-43 proteinopathy
Ito Kawakami et al.
ACTA NEUROPATHOLOGICA (2019)
Alzheimer's disease and other neurodegenerative dementias in comorbidity: A clinical and neuropathological overview
Radoslav Matej et al.
CLINICAL BIOCHEMISTRY (2019)
Neuropathology of dementia in patients with Parkinson's disease: a systematic review of autopsy studies
Callum . Smith et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2019)
Inflammation in ALS/FTD pathogenesis
Madelyn E. McCauley et al.
ACTA NEUROPATHOLOGICA (2019)
C9orf72-generated poly-GR and poly-PR do not directly interfere with nucleocytoplasmic transport
Joni Vanneste et al.
SCIENTIFIC REPORTS (2019)
ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair
Joseph R. Klim et al.
NATURE NEUROSCIENCE (2019)
Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration
Ze'ev Melamed et al.
NATURE NEUROSCIENCE (2019)
Therapeutic Dissolution of Aberrant Phases by Nuclear-Import Receptors
Lin Guo et al.
TRENDS IN CELL BIOLOGY (2019)
Microtubules Deform the Nuclear Membrane and Disrupt Nucleocytoplasmic Transport in Tau-Mediated Frontotemporal Dementia
Francesco Paonessa et al.
CELL REPORTS (2019)
Impaired Nucleoporins Are Present in Sporadic Amyotrophic Lateral Sclerosis Motor Neurons that Exhibit Mislocalization of the 43-kDa TAR DNA-Binding Protein
Hitoshi Aizawa et al.
JOURNAL OF CLINICAL NEUROLOGY (2019)
The coming-of-age of nucleocytoplasmic transport in motor neuron disease and neurodegeneration
Paulo A. Ferreira
CELLULAR AND MOLECULAR LIFE SCIENCES (2019)
Alzheimer's disease
C. A. Lane et al.
EUROPEAN JOURNAL OF NEUROLOGY (2018)
Huntington's disease: a clinical review
P. McColgan et al.
EUROPEAN JOURNAL OF NEUROLOGY (2018)
TDP43 and RNA instability in amyotrophic lateral sclerosis
Kaitlin Weskamp et al.
BRAIN RESEARCH (2018)
Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation
Mario Hofweber et al.
CELL (2018)
Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains
Lin Guo et al.
CELL (2018)
Tau protein liquid-liquid phase separation can initiate tau aggregation
Susanne Wegmann et al.
EMBO JOURNAL (2018)
A Liquid to Solid Phase Transition Underlying Pathological Huntingtin Exon1 Aggregation
Thomas R. Peskett et al.
MOLECULAR CELL (2018)
Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons
Yingxiao Shi et al.
NATURE MEDICINE (2018)
TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD
Ching-Chieh Chou et al.
NATURE NEUROSCIENCE (2018)
Protein Phase Separation: A New Phase in Cell Biology
Steven Boeynaems et al.
TRENDS IN CELL BIOLOGY (2018)
Nuclear egress of TDP-43 and FUS occurs independently of Exportin-1/CRM1
Helena Ederle et al.
SCIENTIFIC REPORTS (2018)
TDP43 nuclear export and neurodegeneration in models of amyotrophic lateral sclerosis and frontotemporal dementia
Hilary C. Archbold et al.
SCIENTIFIC REPORTS (2018)
Linking hnRNP Function to ALS and FTD Pathology Linking hnRNP Function to ALS and FTD Pathology
Maria D. Purice et al.
FRONTIERS IN NEUROSCIENCE (2018)
Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease
Bahareh Eftekharzadeh et al.
NEURON (2018)
Hypertonic Stress Causes Cytoplasmic Translocation of Neuronal, but Not Astrocytic, FUS due to Impaired Transportin Function
Eva-Maria Hock et al.
CELL REPORTS (2018)
ALS/FTD-Linked Mutation in FUS Suppresses Infra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS
Jone Lopez-Erauskin et al.
NEURON (2018)
RNA-Binding Proteins in Amyotrophic Lateral Sclerosis
Melody Zhao et al.
MOLECULES AND CELLS (2018)
Intrinsic disorder in proteins involved in amyotrophic lateral sclerosis
Nikolas Santamaria et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2017)
Tdp-43 cryptic exons are highly variable between cell types
Yun Ha Jeong et al.
MOLECULAR NEURODEGENERATION (2017)
Mechanisms and functions of nuclear envelope remodelling
Rosemarie Ungricht et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)
Polyglutamine-Expanded Huntingtin Exacerbates Age-Related Disruption of Nuclear Integrity and Nucleocytoplasmic Transport
Fatima Gasset-Rosa et al.
NEURON (2017)
Lost in Transportation: Nucleocytoplasmic Transport Defects in ALS and Other Neurodegenerative Diseases
Hong Joo Kim et al.
NEURON (2017)
Mutant Huntingtin Disrupts the Nuclear Pore Complex
Jonathan C. Grima et al.
NEURON (2017)
ABERRANT DISTRIBUTIONS OF NUCLEAR PORE COMPLEX PROTEINS IN ALS MICE AND ALS PATIENTS
Jingwei Shang et al.
NEUROSCIENCE (2017)
Toxic PRn poly-dipeptides encoded by the C9orf72 repeat expansion block nuclear import and export
Kevin Y. Shi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Molecular Architecture of the Major Membrane Ring Component of the Nuclear Pore Complex
Paula Upla et al.
STRUCTURE (2017)
Liquid-liquid phase separation of the microtubule-binding repeats of the Alzheimer-related protein Tau
Susmitha Ambadipudi et al.
NATURE COMMUNICATIONS (2017)
Quantitative analysis of cryptic splicing associated with TDP-43 depletion
Jack Humphrey et al.
BMC MEDICAL GENOMICS (2017)
Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA
Andreas C. Woerner et al.
SCIENCE (2016)
Inside out: the role of nucleocytoplasmic transport in ALS and FTLD
Steven Boeynaems et al.
ACTA NEUROPATHOLOGICA (2016)
Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FUS from ALS-FUS
Marc Suarez-Calvet et al.
ACTA NEUROPATHOLOGICA (2016)
The role of TREX in gene expression and disease
Catherine G. Heath et al.
BIOCHEMICAL JOURNAL (2016)
There has been an awakening: Emerging mechanisms of C9orf72 mutations in FTD/ALS
Aaron D. Gitler et al.
BRAIN RESEARCH (2016)
Structure and Function of the Nuclear Pore Complex Cytoplasmic mRNA Export Platform
Javier Fernandez-Martinez et al.
CELL (2016)
C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles
Kyung-Ha Lee et al.
CELL (2016)
Toxic PR Poly-Dipeptides Encoded by the C9orf72 Repeat Expansion Target LC Domain Polymers
Yi Lin et al.
CELL (2016)
Nucleoporin genes in human diseases
Valeria Nofrini et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2016)
Importin α: a key molecule in nuclear transport and non transport functions
Yoichi Miyamoto et al.
JOURNAL OF BIOCHEMISTRY (2016)
Nuclear transport dysfunction: a common theme in amyotrophic lateral sclerosis and frontotemporal dementia
Ana Jovicic et al.
JOURNAL OF NEUROCHEMISTRY (2016)
A mitotic nuclear envelope tether for Gle1 also affects nuclear and nucleolar architecture
Mahesh Chemudupati et al.
MOLECULAR BIOLOGY OF THE CELL (2016)
Decoding ALS: from genes to mechanism
J. Paul Taylor et al.
NATURE (2016)
C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins
Yong-Jie Zhang et al.
NATURE NEUROSCIENCE (2016)
The expanding biology of the C9orf72 nucleotide repeat expansion in neurodegenerative disease
Aaron R. Haeusler et al.
NATURE REVIEWS NEUROSCIENCE (2016)
Molecular architecture of the inner ring scaffold of the human nuclear pore complex
Jan Kosinski et al.
SCIENCE (2016)
Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease
Aaron Burberry et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain
Alexander E. Conicella et al.
STRUCTURE (2016)
Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD
Steven Boeynaems et al.
SCIENTIFIC REPORTS (2016)
C9orf72 ablation causes immune dysregulation characterized by leukocyte expansion, autoantibody production, and glomerulonephropathy in mice
Amanda Atanasio et al.
SCIENTIFIC REPORTS (2016)
Isoform-Specific Antibodies Reveal Distinct Subcellular Localizations of C9orf72 in Amyotrophic Lateral Sclerosis
Shangxi Xiao et al.
ANNALS OF NEUROLOGY (2015)
The Balbiani Ring Story: Synthesis, Assembly, Processing, and Transport of Specific Messenger RNA-Protein Complexes
Petra Bjork et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 84 (2015)
Promiscuous Binding of Karyopherinβ1 Modulates FG Nucleoporin Barrier Function and Expedites NTF2 Transport Kinetics
Raphael S. Wagner et al.
BIOPHYSICAL JOURNAL (2015)
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
Avinash Patel et al.
CELL (2015)
Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins
Yuan Lin et al.
MOLECULAR CELL (2015)
The C9orf72 repeat expansion disrupts nucleocytoplasmic transport
Ke Zhang et al.
NATURE (2015)
GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport
Brian D. Freibaum et al.
NATURE (2015)
Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS
Ana Jovicic et al.
NATURE NEUROSCIENCE (2015)
Linker Nups connect the nuclear pore complex inner ring with the outer ring and transport channel
Jessica Fischer et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Atomic structure of the Y complex of the nuclear pore
Kotaro Kelley et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD
Jonathan P. Ling et al.
SCIENCE (2015)
Linker Nups connect the nuclear pore complex inner ring with the outer ring and transport channel
Jessica Fischer et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Atomic structure of the Y complex of the nuclear pore
Kotaro Kelley et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
RNA Export through the NPC in Eukaryotes
Masumi Okamura et al.
GENES (2015)
Disruption of the nuclear membrane by perinuclear inclusions of mutant huntingtin causes cell-cycle re-entry and striatal cell death in mouse and cell models of Huntington's disease
Kuan-Yu Liu et al.
HUMAN MOLECULAR GENETICS (2015)
C9ORF72 GGGGCC Expanded Repeats Produce Splicing Dysregulation which Correlates with Disease Severity in Amyotrophic Lateral Sclerosis
Johnathan Cooper-Knock et al.
PLOS ONE (2015)
Transportin-1 and Transportin-2: Protein nuclear import and beyond
Laure Twyffels et al.
FEBS LETTERS (2014)
Reduced C9orf72 protein levels in frontal cortex of amyotrophic lateral sclerosis and frontotemporal degeneration brain with the C9ORF72 hexanucleotide repeat expansion
Adrian J. Waite et al.
NEUROBIOLOGY OF AGING (2014)
Advances in treating amyotrophic lateral sclerosis: insights from pathophysiological studies
Steve Vucic et al.
TRENDS IN NEUROSCIENCES (2014)
Reduced C9orf72 gene expression in c9FTD/ALS is caused by histone trimethylation, an epigenetic event detectable in blood
Veronique V. Belzil et al.
ACTA NEUROPATHOLOGICA (2013)
Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons
Sandra Almeida et al.
ACTA NEUROPATHOLOGICA (2013)
Loss of Function of C9orf72 Causes Motor Deficits in a Zebrafish Model of Amyotrophic Lateral Sclerosis
Sorana Ciura et al.
ANNALS OF NEUROLOGY (2013)
Integrated Structural Analysis of the Human Nuclear Pore Complex Scaffold
Khanh Huy Bui et al.
CELL (2013)
ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules
Caroline Vance et al.
HUMAN MOLECULAR GENETICS (2013)
The DEAD-box Protein Dbp2 Functions with the RNA-Binding Protein Yral to Promote mRNP Assembly
Wai Kit Ma et al.
JOURNAL OF MOLECULAR BIOLOGY (2013)
Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS
Hong Joo Kim et al.
NATURE (2013)
RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention
Christopher J. Donnelly et al.
NEURON (2013)
Converging Mechanisms in ALS and FTD: Disrupted RNA and Protein Homeostasis
Shuo-Chien Ling et al.
NEURON (2013)
Reduced RAN Expression and Disrupted Transport between Cytoplasm and Nucleus; A Key Event in Alzheimer's Disease Pathophysiology
Diego Mastroeni et al.
PLOS ONE (2013)
Protein Arginine Methyltransferase 1 and 8 Interact with FUS to Modify Its Sub-Cellular Distribution and Toxicity In Vitro and In Vivo
Chiara Scaramuzzino et al.
PLOS ONE (2013)
Deletion of C9ORF72 Results in Motor Neuron Degeneration and Stress Sensitivity in C-elegans
Martine Therrien et al.
PLOS ONE (2013)
Expanded GGGGCC repeat RNA associated with amyotrophic lateral sclerosis and frontotemporal dementia causes neurodegeneration
Zihui Xu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration
Clotilde Lagier-Tourenne et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Hexanucleotide Repeats in ALS/FTD Form Length-Dependent RNA Foci, Sequester RNA Binding Proteins, and Are Neurotoxic
Youn-Bok Lee et al.
CELL REPORTS (2013)
Recruitment of TREX to the Transcription Machinery by Its Direct Binding to the Phospho-CTD of RNA Polymerase II
Dominik M. Meinel et al.
PLOS GENETICS (2013)
The Permeability of Reconstituted Nuclear Pores Provides Direct Evidence for the Selective Phase Model
Bastian B. Huelsmann et al.
CELL (2012)
Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS
Dorothee Dormann et al.
EMBO JOURNAL (2012)
Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations
Miranda L. Tradewell et al.
HUMAN MOLECULAR GENETICS (2012)
Nucleoporin Nup50 Stabilizes Closed Conformation of Armadillo repeat 10 in Importin α5
Ruth A. Pumroy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Requirements for Stress Granule Recruitment of Fused in Sarcoma (FUS) and TAR DNA-binding Protein of 43 kDa (TDP-43)
Eva Bentmann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
A C9orf72 promoter repeat expansion in a Flanders-Belgian cohort with disorders of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum: a gene identification study
Ilse Gijselinck et al.
LANCET NEUROLOGY (2012)
Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs
Clotilde Lagier-Tourenne et al.
NATURE NEUROSCIENCE (2012)
Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export
Divyang Jani et al.
NUCLEIC ACIDS RESEARCH (2012)
The Effect of PRMT1-Mediated Arginine Methylation on the Subcellular Localization, Stress Granules, and Detergent-Insoluble Aggregates of FUS/TLS
Atsushi Yamaguchi et al.
PLOS ONE (2012)
Nuclear export of single native mRNA molecules observed by light sheet fluorescence microscopy
Jan Peter Siebrasse et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Structural and energetic basis of ALS-causing mutations in the atypical proline-tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS)
Zi Chao Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
The Human Nuclear Pore Complex as Revealed by Cryo-Electron Tomography
Tal Maimon et al.
STRUCTURE (2012)
The Structure of the Nuclear Pore Complex
Andre Hoelz et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 80 (2011)
Nuclear import by karyopherin-βs: Recognition and inhibition
Yuh Min Chook et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)
Amyloid-like Aggregates Sequester Numerous Metastable Proteins with Essential Cellular Functions
Heidi Olzscha et al.
CELL (2011)
TDP-43 and FUS/TLS: cellular functions and implications for neurodegeneration
Fabienne C. Fiesel et al.
FEBS JOURNAL (2011)
TAR DNA-binding protein 43 (TDP-43) regulates stress granule dynamics via differential regulation of G3BP and TIA-1
Karli K. McDonald et al.
HUMAN MOLECULAR GENETICS (2011)
Localization of Pom121 to the inner nuclear membrane is required for an early step of interphase nuclear pore complex assembly
Tomoko Funakoshi et al.
MOLECULAR BIOLOGY OF THE CELL (2011)
Nuclear localization sequence of FUS and induction of stress granules by ALS mutants
Jozsef Gal et al.
NEUROBIOLOGY OF AGING (2011)
Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
Mariely DeJesus-Hernandez et al.
NEURON (2011)
A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
Alan E. Renton et al.
NEURON (2011)
Huntington's Disease
Steven Finkbeiner
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)
The role of the nuclear pore complex in aging of post-mitotic cells
Martin W. Hetzer
AGING-US (2010)
Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration
Agnes L. Nishimura et al.
BRAIN (2010)
mRNA Export from Mammalian Cell Nuclei Is Dependent on GANP
Vihandha O. Wickramasinghe et al.
CURRENT BIOLOGY (2010)
ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import
Dorothee Dormann et al.
EMBO JOURNAL (2010)
Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules
Daryl A. Bosco et al.
HUMAN MOLECULAR GENETICS (2010)
TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration
Clotilde Lagier-Tourenne et al.
HUMAN MOLECULAR GENETICS (2010)
TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia
Ian R. A. Mackenzie et al.
LANCET NEUROLOGY (2010)
FUS GENE MUTATIONS IN FAMILIAL AND SPORADIC AMYOTROPHIC LATERAL SCLEROSIS
Rosa Rademakers et al.
MUSCLE & NERVE (2010)
The mechanism of eukaryotic translation initiation and principles of its regulation
Richard J. Jackson et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Arginine methylation of REF/ALY promotes efficient handover of mRNA to TAP/NXF1
Ming-Lung Hung et al.
NUCLEIC ACIDS RESEARCH (2010)
Comparative Genomic Evidence for a Complete Nuclear Pore Complex in the Last Eukaryotic Common Ancestor
Nadja Neumann et al.
PLOS ONE (2010)
The multiple roles of TDP-43 in pre-mRNA processing and gene expression regulation
Emanuele Buratti et al.
RNA BIOLOGY (2010)
Expanding the Definition of the Classical Bipartite Nuclear Localization Signal
Allison Lange et al.
TRAFFIC (2010)
The Nuclear Pore Complex and Nuclear Transport
Susan R. Wente et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)
A Protein Inventory of Human Ribosome Biogenesis Reveals an Essential Function of Exportin 5 in 60S Subunit Export
Thomas Wild et al.
PLOS BIOLOGY (2010)
GANP enhances the efficiency of mRNA nuclear export in mammalian cells
Vihandha O. Wickramasinghe et al.
NUCLEUS-AUSTIN (2010)
A new subtype of frontotemporal lobar degeneration with FUS pathology
Manuela Neumann et al.
BRAIN (2009)
PRMT1 mediated methylation of TAF15 is required for its positive gene regulatory function
Laure Jobert et al.
EXPERIMENTAL CELL RESEARCH (2009)
Molecular Neuropathology of TDP-43 Proteinopathies
Manuela Neumann
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2009)
Nuclear Contour Irregularity and Abnormal Transporter Protein Distribution in Anterior Horn Cells in Amyotrophic Lateral Sclerosis
Yoshimi Kinoshita et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2009)
Evidence for a Shared Nuclear Pore Complex Architecture That Is Conserved from the Last Common Eukaryotic Ancestor
Jeffrey A. DeGrasse et al.
MOLECULAR & CELLULAR PROTEOMICS (2009)
The Three Fungal Transmembrane Nuclear Pore Complex Proteins of Aspergillus nidulans Are Dispensable in the Presence of an Intact An-Nup84-120 Complex
Hui-Lin Liu et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
TDP-43 is consistently co-localized with ubiquitinated inclusions in sporadic and Guam amyotrophic lateral sclerosis but not in familial amyotrophic lateral sclerosis with and without SOD1 mutations
Satomi Maekawa et al.
NEUROPATHOLOGY (2009)
Identification of a selective nuclear import signal in adenosine deaminases acting on RNA
Stefan Maas et al.
NUCLEIC ACIDS RESEARCH (2009)
Novel Exon of Mammalian ADAR2 Extends Open Reading Frame
Stefan Maas et al.
PLOS ONE (2009)
Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity
Yong-Jie Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Proteomic Analysis of Methylarginine-Containing Proteins in HeLa Cells by Two-Dimensional Gel Electrophoresis and Immunoblotting with a Methylarginine-Specific Antibody
Chien-Jen Hung et al.
PROTEIN JOURNAL (2009)
Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6
Caroline Vance et al.
SCIENCE (2009)
Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis
T. J. Kwiatkowski et al.
SCIENCE (2009)
Structural determinants of the cellular localization and shuttling of TDP-43
Youhna M. Ayala et al.
JOURNAL OF CELL SCIENCE (2008)
Importins and exportins in cellular differentiation
Norihisa Okada et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2008)
Crossing the nuclear envelope: Hierarchical regulation of nucleocytoplasmic transport
Laura J. Terry et al.
SCIENCE (2007)
The molecular architecture of the nuclear pore complex
Frank Alber et al.
NATURE (2007)
Exporting RNA from the nucleus to the cytoplasm
Alwin Koehler et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Lack of TDP-43 abnormalities in mutant SOD1 transgenic mice shows disparity with ALS
Janice Robertson et al.
NEUROSCIENCE LETTERS (2007)
TDP-43 immunoreactivity in neuronal inclusions in familial amyotrophic lateral sclerosis with or without SOD1 gene mutation
Chun-Feng Tan et al.
ACTA NEUROPATHOLOGICA (2007)
Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations
Ian R. A. Mackenzie et al.
ANNALS OF NEUROLOGY (2007)
Molecular mechanism of the nuclear protein import cycle
Murray Stewart
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Systematic deletion and mitotic localization of the nuclear pore complex proteins of Aspergillus nidulans
Aysha H. Osmani et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Manuela Neumann et al.
SCIENCE (2006)
Rules for nuclear localization sequence recognition by karyopherinβ2
Brittany J. Lee et al.
CELL (2006)
Activation of the DExD/H-box protein Dbp5 by the nuclear-pore protein Gle1 and its coactivator InsP6 is required for mRNA export
Christine S. Weirich et al.
NATURE CELL BIOLOGY (2006)
Inositol hexakisphosphate and Gle1 activate the DEAD-box protein Dbp5 for nuclear mRNA export
Abel R. Alcazar-Roman et al.
NATURE CELL BIOLOGY (2006)
The conserved transmembrane nucleoporin NDC1 is required for nuclear pore complex assembly in vertebrate cells
J Mansfeld et al.
MOLECULAR CELL (2006)
Nuclear pore complex proteins in Alzheimer disease
LG Sheffield et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2006)
Distinct functional domains within nucleoporins Nup153 and Nup98 mediate transcription-dependent mobility
ER Griffis et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
Minimal nuclear pore complexes define FG repeat domains essential for transport
LA Strawn et al.
NATURE CELL BIOLOGY (2004)
Yeast nuclear pore complexes have a cytoplasmic ring and internal filaments
E Kiseleva et al.
JOURNAL OF STRUCTURAL BIOLOGY (2004)
Nucleocytoplasmic transport: taking an inventory
H Fried et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2003)
Detection of arginine dimethylated peptides by parallel precursor ion scanning mass spectrometry in positive ion mode
J Rappsilber et al.
ANALYTICAL CHEMISTRY (2003)
Characterization of Ran-driven cargo transport and the RanGTPase system by kinetic measurements and computer simulation
D Görlich et al.
EMBO JOURNAL (2003)
Proteomic analysis of the mammalian nuclear pore complex
JA Cronshaw et al.
JOURNAL OF CELL BIOLOGY (2002)
The permeability barrier of nuclear pore complexes appears to operate via hydrophobic exclusion
K Ribbeck et al.
EMBO JOURNAL (2002)
Modular self-assembly of a Y-shaped multiprotein complex from seven nucleoporins
M Lutzmann et al.
EMBO JOURNAL (2002)
Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor
S Fribourg et al.
MOLECULAR CELL (2001)
Identities of sequestered proteins in aggregates from cells with induced polyglutamine expression
ST Suhr et al.
JOURNAL OF CELL BIOLOGY (2001)
REF proteins mediate the export of spliced and unspliced mRNAs from the nucleus
JP Rodrigues et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture
A Herold et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Crystallization and initial X-ray diffraction characterization of complexes of FxFG nucleoporin repeats with nuclear transport factors
R Bayliss et al.
JOURNAL OF STRUCTURAL BIOLOGY (2000)
Structural basis for the interaction between FxFG nucleoporin repeats and importin-β in nuclear trafficking
R Bayliss et al.
CELL (2000)
分享论文
