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Collagen-targeted MRI contrast agent for liver fibrosis detection

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NATURE RESEARCH
DOI: 10.1038/s41575-020-0266-z

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  1. NIDDK NIH HHS [R01 DK113272] Funding Source: Medline

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A novel MRI gadolinium-based contrast agent designed to bind with collagen, a key component in liver fibrosis progression, provides direct quantification of collagen deposition in several preclinical liver disease models. This tool could have large implications in clinical diagnosis and drug trials.

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