期刊
NATURE REVIEWS ENDOCRINOLOGY
卷 16, 期 3, 页码 133-134出版社
NATURE RESEARCH
DOI: 10.1038/s41574-020-0319-y
关键词
-
资金
- Intramural Research Program of the National Institute on Aging
A discovery metabolomic study was performed in a large cohort of adults to identify circulating biomarkers of frailty. The study found that carnitine and vitamin E pathways were dysregulated in frail compared with non-frail participants. These findings point to dysregulated mitochondrial metabolism as a potential root of age-related frailty.
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