相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Association between metabolic profiles in urine and bone mineral density of pre- and postmenopausal Chinese women
Lisha Yu et al.
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (2019)
Role of Epigenomics in Bone and Cartilage Disease
Joyce B. J. van Meurs et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2019)
Joint Association Analysis Identified 18 New Loci for Bone Mineral Density
Yu-Fang Pei et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2019)
A Bayesian framework that integrates multi-omics data and gene networks predicts risk genes from schizophrenia GWAS data
Quan Wang et al.
NATURE NEUROSCIENCE (2019)
Chemokine receptor 3 is a negative regulator of trabecular bone mass in female mice
Subburaman Mohan et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2019)
The Long Non-coding RNA-ORLNC1 Regulates Bone Mass by Directing Mesenchymal Stem Cell Fate
Lei Yang et al.
MOLECULAR THERAPY (2019)
An atlas of genetic influences on osteoporosis in humans and mice
John A. Morris et al.
NATURE GENETICS (2019)
Dissecting the Genetics of Osteoporosis using Systems Approaches
Basel M. Al-Barghouthi et al.
TRENDS IN GENETICS (2019)
Genome-scale Capture C promoter interactions implicate effector genes at GWAS loci for bone mineral density
Alessandra Chesi et al.
NATURE COMMUNICATIONS (2019)
Single-Cell (Multi)omics Technologies
Lia Chappell et al.
ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, VOL 19 (2018)
Primary Osteoporosis Is Not Reflected by Disease-Specific DNA Methylation or Accelerated Epigenetic Age in Blood
Eduardo Fernandez-Rebollo et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2018)
Genetic architecture: the shape of the genetic contribution to human traits and disease
Nicholas J. Timpson et al.
NATURE REVIEWS GENETICS (2018)
Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects
Carolina Medina-Gomez et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2018)
An Osteoporosis Risk SNP at 1p36.12 Acts as an Allele-Specific Enhancer to Modulate LINC00339 Expression via Long-Range Loop Formation
Xiao-Feng Chen et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2018)
Integration of summary data from GWAS and eQTL studies identified novel causal BMD genes with functional predictions
Xiang-He Meng et al.
BONE (2018)
Hsa_Circ_0001275: A Potential Novel Diagnostic Biomarker for Postmenopausal Osteoporosis
Kewei Zhao et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)
Metabolomic Pathways to Osteoporosis in Middle-Aged Women: A Genome-Metabolome-Wide Mendelian Randomization Study
Alireza Moayyeri et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2018)
Expression Quantitative Trait Locus Study of Bone Mineral Density GWAS Variants in Human Osteoclasts
Benjamin H. Mullin et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2018)
Multiple Functional Variants at 13q14 Risk Locus for Osteoporosis Regulate RANKL Expression Through Long-Range Super-Enhancer
Dong-Li Zhu et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2018)
Assessing the Associations of Blood Metabolites With Osteoporosis: A Mendelian Randomization Study
Li Liu et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2018)
From genome-wide associations to candidate causal variants by statistical fine-mapping
Daniel J. Schaid et al.
NATURE REVIEWS GENETICS (2018)
Targeted reversion of induced pluripotent stem cells from patients with human cleidocranial dysplasia improves bone regeneration in a rat calvarial bone defect model
Akiko Saito et al.
STEM CELL RESEARCH & THERAPY (2018)
Association of Plasma Lipids and Polar Metabolites with Low Bone Mineral Density in Singaporean-Chinese Menopausal Women: A Pilot Study
Diana Cabrera et al.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2018)
Osteomicrobiology: The influence of gut microbiota on bone in health and disease
Rheinallt M. Jones et al.
BONE (2018)
Identification of the Human Skeletal Stem Cell
Charles K. F. Chan et al.
CELL (2018)
Metabolomic profiles associated with bone mineral density in US Caucasian women
Qi Zhao et al.
NUTRITION & METABOLISM (2018)
Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomisation study
Katerina Trajanoska et al.
BMJ-BRITISH MEDICAL JOURNAL (2018)
Gene-based GWAS analysis for consecutive studies of GEFOS
W. Zhu et al.
OSTEOPOROSIS INTERNATIONAL (2018)
Long Non-coding RNAs: A New Regulatory Code for Osteoporosis
Qian-Yuan Wu et al.
FRONTIERS IN ENDOCRINOLOGY (2018)
Heritability and Genetic Correlations for Bone Microarchitecture: The Framingham Study Families
David Karasik et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2017)
Prediction of Bone Mineral Density and Fragility Fracture by Genetic Profiling
Thao P. Ho-Le et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2017)
Mass spectrometry based proteomics profiling of human monocytes
Yong Zeng et al.
PROTEIN & CELL (2017)
Distinct DNA methylation profiles in bone and blood of osteoporotic and healthy postmenopausal women
Sjur Reppe et al.
EPIGENETICS (2017)
Regulatory element-based prediction identifies new susceptibility regulatory variants for osteoporosis
Shi Yao et al.
HUMAN GENETICS (2017)
A Statistical Approach to Fine Mapping for the Identification of Potential Causal Variants Related to Bone Mineral Density
Jonathan Greenbaum et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2017)
Epigenome-wide Association of DNA Methylation in Whole Blood With Bone Mineral Density
John A. Morris et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2017)
Association Between Gut Microbiota and Bone Health: Potential Mechanisms and Prospective
Yuan-Cheng Chen et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2017)
Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis
John P. Kemp et al.
NATURE GENETICS (2017)
Using GWAS to identify novel therapeutic targets for osteoporosis
Olivia L. Sabik et al.
TRANSLATIONAL RESEARCH (2017)
Cell-type deconvolution in epigenome-wide association studies: a review and recommendations
Andrew E. Teschendorff et al.
EPIGENOMICS (2017)
Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus
Carolina Medina-Gomez et al.
NATURE COMMUNICATIONS (2017)
Integrating GWAS and Co-expression Network Data Identifies Bone Mineral Density Genes SPTBN1 and MARK3 and an Osteoblast Functional Module
Gina M. Calabrese et al.
CELL SYSTEMS (2017)
Prospects of Fine-Mapping Trait-Associated Genomic Regions by Using Summary Statistics from Genome-wide Association Studies
Christian Benner et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2017)
An Expanded View of Complex Traits: From Polygenic to Omnigenic
Evan A. Boyle et al.
CELL (2017)
Increased detection of genetic loci associated with risk predictors of osteoporotic fracture using a pleiotropic cFDR method
Jonathan Greenbaum et al.
BONE (2017)
Multi-omics approaches to disease
Yehudit Hasin et al.
GENOME BIOLOGY (2017)
A new method for estimating effect size distribution and heritability from genome-wide association summary results
Lei Zhang et al.
HUMAN GENETICS (2016)
RNA mis-splicing in disease
Marina M. Scotti et al.
NATURE REVIEWS GENETICS (2016)
Network-based proteomic analysis for postmenopausal osteoporosis in Caucasian females
Lan Zhang et al.
PROTEOMICS (2016)
Colocalization of GWAS and eQTL Signals Detects Target Genes
Farhad Hormozdiari et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2016)
FINEMAP: efficient variable selection using summary data from genome-wide association studies
Christian Benner et al.
BIOINFORMATICS (2016)
Epigenetic Mechanisms in Bone Biology and Osteoporosis: Can They Drive Therapeutic Choices?
Francesca Marini et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
Integrative Analysis of Genomics and Transcriptome Data to Identify Potential Functional Genes of BMDs in Females
Yuan-Cheng Chen et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2016)
Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2
Carrie M. Nielson et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2016)
Prediction of Future Osteoporotic Fracture Occurrence by Genetic Profiling: A 6-Year Follow-Up Observational Study
Seung Hun Lee et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2016)
Rapid phenotyping of knockout mice to identify genetic determinants of bone strength
Bernard Freudenthal et al.
JOURNAL OF ENDOCRINOLOGY (2016)
The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits
Aldons J. Lusis et al.
JOURNAL OF LIPID RESEARCH (2016)
Quantitative proteomics and integrative network analysis identified novel genes and pathways related to osteoporosis
Yong Zeng et al.
JOURNAL OF PROTEOMICS (2016)
Untargeted Metabolomics Strategies-Challenges and Emerging Directions
Alexandra C. Schrimpe-Rutledge et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2016)
Metabolomics: beyond biomarkers and towards mechanisms
Caroline H. Johnson et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2016)
Deficiency of ATP6V1H Causes Bone Loss by Inhibiting Bone Resorption and Bone Formation through the TGF-β1 Pathway
Xiaohong Duan et al.
THERANOSTICS (2016)
Methylation of Bone SOST, Its mRNA, and Serum Sclerostin Levels Correlate Strongly With Fracture Risk in Postmenopausal Women
Sjur Reppe et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2015)
Integrative analysis of 111 reference human epigenomes
Anshul Kundaje et al.
NATURE (2015)
Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture
Hou-Feng Zheng et al.
NATURE (2015)
The support of human genetic evidence for approved drug indications
Matthew R. Nelson et al.
NATURE GENETICS (2015)
Lrp4 in osteoblasts suppresses bone formation and promotes osteoclastogenesis and bone resorption
Lei Xiong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Donepezil prevents RANK-induced bone loss via inhibition of osteoclast differentiation by downregulating acetylcholinesterase
Tsuyoshi Sato et al.
HELIYON (2015)
Is GSN significant for hip BMD in female Caucasians?
Fei-Yan Deng et al.
BONE (2014)
Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium
Alireza Moayyeri et al.
HUMAN MOLECULAR GENETICS (2014)
Association Between the Metabolome and Low Bone Mineral Density in Taiwanese Women Determined by 1H NMR Spectroscopy
Ying-Shu You et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2014)
The Recent Prevalence of Osteoporosis and Low Bone Mass in the United States Based on Bone Mineral Density at the Femoral Neck or Lumbar Spine
Nicole C. Wright et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2014)
New Reference Data on Bone Mineral Density and the Prevalence of Osteoporosis in Korean Adults Aged 50 Years or Older: The Korea National Health and Nutrition Examination Survey 2008-2010
Kyung-Shik Lee et al.
JOURNAL OF KOREAN MEDICAL SCIENCE (2014)
Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
Claudia Giambartolomei et al.
PLOS GENETICS (2014)
Integrating Functional Data to Prioritize Causal Variants in Statistical Fine-Mapping Studies
Gleb Kichaev et al.
PLOS GENETICS (2014)
Accounting for cellular heterogeneity is critical in epigenome-wide association studies
Andrew E. Jaffe et al.
GENOME BIOLOGY (2014)
Osteoporosis and Alzheimer pathology: role of cellular stress response and hormetic redox signaling in aging and bone remodeling
Carolin Cornelius et al.
FRONTIERS IN PHARMACOLOGY (2014)
High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes
Robert Brommage et al.
BONE RESEARCH (2014)
Genome-wide profiling of bone reveals differentially methylated regions in osteoporosis and osteoarthritis
Jesus Delgado-Calle et al.
ARTHRITIS AND RHEUMATISM (2013)
The Osteocyte: An Endocrine Cell . . . and More
Sarah L. Dallas et al.
ENDOCRINE REVIEWS (2013)
Inactivation of estrogen receptor α in bone-forming cells induces bone loss in female mice
Jorma A. Maatta et al.
FASEB JOURNAL (2013)
Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women
Daniel L. Koller et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2013)
Swedish Mutant APP Suppresses Osteoblast Differentiation and Causes Osteoporotic Deficit, Which Are Ameliorated by N-Acetyl-L-Cysteine
Wen-Fang Xia et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2013)
On Genome-Wide Association Studies and Their Meta-Analyses: Lessons Learned From Osteoporosis Studies
Yong-Jun Liu et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2013)
Genome-wide expression profiles of subchondral bone in osteoarthritis
Ching-Heng Chou et al.
ARTHRITIS RESEARCH & THERAPY (2013)
Annotation of functional variation in personal genomes using RegulomeDB
Alan P. Boyle et al.
GENOME RESEARCH (2012)
Susceptibility Genes for Osteoporotic Fracture in Postmenopausal Chinese Women
Chun Wang et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2012)
Serum Sclerostin and Risk of Hip Fracture in Older Caucasian Women
Aarthi Arasu et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)
Twins and the mystery of missing heritability: the contribution of gene-environment interactions
J. Kaprio
JOURNAL OF INTERNAL MEDICINE (2012)
What makes UK Biobank special?
Rory Collins
LANCET (2012)
An integrated encyclopedia of DNA elements in the human genome
Ian Dunham et al.
NATURE (2012)
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture
Karol Estrada et al.
NATURE GENETICS (2012)
DISEASE MECHANISMS Genetics of osteoporosis from genome-wide association studies: advances and challenges
J. Brent Richards et al.
NATURE REVIEWS GENETICS (2012)
Building strong bones: molecular regulation of the osteoblast lineage
Fanxin Long
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jinek et al.
SCIENCE (2012)
Systematic Localization of Common Disease-Associated Variation in Regulatory DNA
Matthew T. Maurano et al.
SCIENCE (2012)
Systems Genetic Analysis of Osteoblast-Lineage Cells
Gina Calabrese et al.
PLOS GENETICS (2012)
Intercellular Cross-Talk Among Bone Cells: New Factors and Pathways
Natalie A. Sims et al.
CURRENT OSTEOPOROSIS REPORTS (2012)
GCTA: A Tool for Genome-wide Complex Trait Analysis
Jian Yang et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2011)
An Integrative Study Ascertained SOD2 as a Susceptibility Gene for Osteoporosis in Chinese
Fei-Yan Deng et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2011)
Bone remodelling at a glance
Julie C. Crockett et al.
JOURNAL OF CELL SCIENCE (2011)
Peripheral Blood Monocyte-expressed ANXA2 Gene is Involved in Pathogenesis of Osteoporosis in Humans
Fei-Yan Deng et al.
MOLECULAR & CELLULAR PROTEOMICS (2011)
MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo
Tilde Eskildsen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Pathway-Based Genome-Wide Association Analysis Identified the Importance of Regulation-of-Autophagy Pathway for Ultradistal Radius BMD
Lishu Zhang et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2010)
New approaches to population stratification in genome-wide association studies
Alkes L. Price et al.
NATURE REVIEWS GENETICS (2010)
Genome-wide Association and Follow-Up Replication Studies Identified ADAMTS18 and TGFBR3 as Bone Mass Candidate Genes in Different Ethnic Groups
Dong-Hai Xiong et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2009)
Collaborative Meta-analysis: Associations of 150 Candidate Genes With Osteoporosis and Osteoporotic Fracture
J. Brent Richards et al.
ANNALS OF INTERNAL MEDICINE (2009)
Effects of a synonymous variant in exon 9 of the CD44 gene on pre-mRNA splicing in a family with osteoporosis
Christopher Vidal et al.
BONE (2009)
Population genomics in a disease targeted primary cell model
Elin Grundberg et al.
GENOME RESEARCH (2009)
New sequence variants associated with bone mineral density
Unnur Styrkarsdottir et al.
NATURE GENETICS (2009)
Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies
Fernando Rivadeneira et al.
NATURE GENETICS (2009)
Failure to Replicate a Genetic Association May Provide Important Clues About Genetic Architecture
Casey S. Greene et al.
PLOS ONE (2009)
Replication in Genome-Wide Association Studies
Peter Kraft et al.
STATISTICAL SCIENCE (2009)
Genome-wide Copy-Number-Variation Study Identified a Susceptibility Gene, UGT2B17, for Osteoporosis
Tie-Lin Yang et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2008)
WGCNA: an R package for weighted correlation network analysis
Peter Langfelder et al.
BMC BIOINFORMATICS (2008)
Serum biomarker profile associated with high bone turnover and BMD in postmenopausal women
Sudeepa Bhattacharyya et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2008)
Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study
J. B. Richards et al.
LANCET (2008)
Multiple genetic loci for bone mineral density and fractures
Unnur Styrkarsdottir et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Proteomic analysis of circulating monocytes in Chinese premenopausal females with extremely discordant bone mineral density
Fei-Yan Deng et al.
PROTEOMICS (2008)
Tibial subchondral bone size and knee cartilage defects: relevance to knee osteoarthritis
C. Ding et al.
OSTEOARTHRITIS AND CARTILAGE (2007)
Pathogenesis of osteoporosis: concepts, conflicts, and prospects
LG Raisz
JOURNAL OF CLINICAL INVESTIGATION (2005)
A novel pathophysiological mechanism for osteoporosis suggested by an in vivo gene expression study of circulating monocytes
YZ Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Predictive value of BMD for hip and other fractures
O Johnell et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2005)
Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling
XF Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Estrogen responsiveness of bone formation in vitro and altered bone phenotype in aged estrogen receptor-α-deficient male and female mice
V Parikka et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY (2005)
The osteocyte
MLK Tate et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
Dexamethasone enhances osteoclast formation synergistically with transforming growth factor-β by stimulating the priming of osteoclast progenitors for differentiation into osteoclasts
A Takuma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Osteoclast differentiation and activation
WJ Boyle et al.
NATURE (2003)
Targeted deletion of histidine decarboxylase gene in mice increases bone formation and protects against ovariectomy-induced bone loss
LA Fitzpatrick et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Genetics of osteoporosis
M Peacock et al.
ENDOCRINE REVIEWS (2002)
Relevance of the genes for bone mass variation to susceptibility to osteoporotic fractures and its implications to gene search for complex human diseases
HW Deng et al.
GENETIC EPIDEMIOLOGY (2002)