相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Microglial Function Is Distinct in Different Anatomical Locations during Retinal Homeostasis and Degeneration
Emily G. O'Koren et al.
IMMUNITY (2019)
Impaired αVβ8 and TGFβ signaling lead to microglial dysmaturation and neuromotor dysfunction
Thomas D. Arnold et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2019)
Increased synapse elimination by microglia in schizophrenia patient-derived models of synaptic pruning
Carl M. Sellgren et al.
NATURE NEUROSCIENCE (2019)
Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation
Marta Joana Costa Jordao et al.
SCIENCE (2019)
Bi-allelic CSF1R Mutations Cause Skeletal Dysplasia of Dysosteosclerosis-Pyle Disease Spectrum and Degenerative Encephalopathy with Brain Malformation
Long Guo et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2019)
Homozygous Mutations in CSF1R Cause a Pediatric-Onset Leukoencephalopathy and Can Result in Congenital Absence of Microglia
Nynke Oosterhof et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2019)
A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment
Hannah Van Hove et al.
NATURE NEUROSCIENCE (2019)
Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo
Jonathan Hasselmann et al.
NEURON (2019)
Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations
Rocio Rojo et al.
NATURE COMMUNICATIONS (2019)
Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells
Zhaoyuan Liu et al.
CELL (2019)
Anti-human CD117 antibody-mediated bone marrow niche clearance in nonhuman primates and humanized NSG mice
Hye-Sook Kwon et al.
BLOOD (2019)
Methotrexate Chemotherapy Induces Persistent Tri-glial Dysregulation that Underlies Chemotherapy-Related Cognitive Impairment
Erin M. Gibson et al.
CELL (2019)
Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes
Timothy R. Hammond et al.
IMMUNITY (2019)
Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing
Qingyun Li et al.
NEURON (2019)
Tmem119-EGFP and Tmem119-CreERT2 transgenic mice for labeling and manipulating microglia
Tobias Kaiser et al.
ENEURO (2019)
Diagnostic criteria for adult-onset leukoencephalopathy with axonal spheroids and pigmented glia due to CSF1R mutation
T. Konno et al.
EUROPEAN JOURNAL OF NEUROLOGY (2018)
Long-Term Functional Outcomes after Hematopoietic Stem Cell Transplant for Early Infantile Krabbe Disease
Heather Allewelt et al.
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2018)
Blood Development: Hematopoietic Stem Cell Dependence and Independence
Elaine Dzierzak et al.
CELL STEM CELL (2018)
Two distinct ontogenies confer heterogeneity to mouse brain microglia
Shrutokirti De et al.
DEVELOPMENT (2018)
Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner
Moumita Datta et al.
IMMUNITY (2018)
Peripherally derived macrophages can engraft the brain independent of irradiation and maintain an identity distinct from microglia
James C. Cronk et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2018)
Fatal demyelinating disease is induced by monocyte-derived macrophages in the absence of TGF-beta signaling
Harald Lund et al.
NATURE IMMUNOLOGY (2018)
Re-evaluating microglia expression profiles using RiboTag and cell isolation strategies
Zhana Haimon et al.
NATURE IMMUNOLOGY (2018)
Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson's disease
Seung Pil Yun et al.
NATURE MEDICINE (2018)
Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion
Yubin Huang et al.
NATURE NEUROSCIENCE (2018)
Epigenetic regulation of brain region-specific microglia clearance activity
Pinar Ayata et al.
NATURE NEUROSCIENCE (2018)
Modelling microglial function with induced pluripotent stem cells: an update
Jennifer M. Pocock et al.
NATURE REVIEWS NEUROSCIENCE (2018)
A Combination of Ontogeny and CNS Environment Establishes Microglial Identity
F. Chris Bennett et al.
NEURON (2018)
Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer's Disease Not Evident in Mouse Models
Brad A. Friedman et al.
CELL REPORTS (2018)
Sex-Specific Features of Microglia from Adult Mice
Alessandro Villa et al.
CELL REPORTS (2018)
Embryonic Microglia Derive from Primitive Macrophages and Are Replaced by cmyb-Dependent Definitive Microglia in Zebrafish
Giuliano Ferrero et al.
CELL REPORTS (2018)
Repopulating retinal microglia restore endogenous organization and function under CX3CL1-CX3CR1 regulation
Yikui Zhang et al.
SCIENCE ADVANCES (2018)
Brain region-specific enhancement of remyelination and prevention of demyelination by the CSF1R kinase inhibitor BLZ945
Nicolau Beckmann et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2018)
Erythro-myeloid progenitors contribute endothelial cells to blood vessels
Alice Plein et al.
NATURE (2018)
Microglia in neurodegeneration
Suzanne Hickman et al.
NATURE NEUROSCIENCE (2018)
Microglia and the Brain: Complementary Partners in Development and Disease
Timothy R. Hammond et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 34 (2018)
Competitive repopulation of an empty microglial niche yields functionally distinct subsets of microglia-like cells
Harald Lund et al.
NATURE COMMUNICATIONS (2018)
Engrafted parenchymal brain macrophages differ from microglia in transcriptome, chromatin landscape and response to challenge
Anat Shemer et al.
NATURE COMMUNICATIONS (2018)
Microglia innately develop within cerebral organoids
Paul R. Ormel et al.
NATURE COMMUNICATIONS (2018)
Microglia and macrophages in brain homeostasis and disease
Qingyun Li et al.
NATURE REVIEWS IMMUNOLOGY (2018)
Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function
Kazuyuki Takata et al.
IMMUNITY (2017)
Cell-specific deletion of C1qa identifies microglia as the dominant source of C1q in mouse brain
Maria I. Fonseca et al.
JOURNAL OF NEUROINFLAMMATION (2017)
A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease
Elvira Mass et al.
NATURE (2017)
Neurotoxic reactive astrocytes are induced by activated microglia
Shane A. Liddelow et al.
NATURE (2017)
Differentiation of human and murine induced pluripotent stem cells to microglia-like cells
Hetal Pandya et al.
NATURE NEUROSCIENCE (2017)
Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging
Petra Fueger et al.
NATURE NEUROSCIENCE (2017)
A new fate mapping system reveals context-dependent random or clonal expansion of microglia
Tuan Leng Tay et al.
NATURE NEUROSCIENCE (2017)
iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases
Edsel M. Abud et al.
NEURON (2017)
The Complicated Relationship between Gaucher Disease and Parkinsonism: Insights from a Rare Disease
Elma Aflaki et al.
NEURON (2017)
Local Cues Establish and Maintain Region-Specific Phenotypes of Basal Ganglia Microglia
Lindsay M. De Biase et al.
NEURON (2017)
Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-Medium Cultures
Christopher J. Bohlen et al.
NEURON (2017)
An environment-dependent transcriptional network specifies human microglia identity
David Gosselin et al.
SCIENCE (2017)
The Lifespan and Turnover of Microglia in the Human Brain
Pedro Reu et al.
CELL REPORTS (2017)
Coupled Proliferation and Apoptosis Maintain the Rapid Turnover of Microglia in the Adult Brain
Katharine Askew et al.
CELL REPORTS (2017)
A novel microglial subset plays a key role in myelinogenesis in developing brain
Agnieszka Wlodarczyk et al.
EMBO JOURNAL (2017)
A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease
Hadas Keren-Shaul et al.
CELL (2017)
Mice deficient in NRROS show abnormal microglial development and neurological disorders
Kit Wong et al.
NATURE IMMUNOLOGY (2017)
Neurons exhibit Lyz2 promoter activity in vivo: Implications for using LysM-Cre mice in myeloid cell research
Johannes Orthgiess et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2016)
Yolk Sac Macrophages, Fetal Liver, and Adult Monocytes Can Colonize an Empty Niche and Develop into Functional Tissue-Resident Macrophages
Lianne van de laar et al.
IMMUNITY (2016)
Screening of Newborns for Disorders with High Benefit-Risk Ratios Should Be Mandatory
Nicole Kelly et al.
JOURNAL OF LAW MEDICINE & ETHICS (2016)
Sall1 is a transcriptional regulator defining microglia identity and function
Anne Buttgereit et al.
NATURE IMMUNOLOGY (2016)
Origin, fate and dynamics of macrophages at central nervous system interfaces
Tobias Goldmann et al.
NATURE IMMUNOLOGY (2016)
Efficient derivation of microglia-like cells from human pluripotent stem cells
Julien Muffat et al.
NATURE MEDICINE (2016)
Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse
Ye Zhang et al.
NEURON (2016)
New tools for studying microglia in the mouse and human CNS
Mariko L. Bennett et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Microglia development follows a stepwise program to regulate brain homeostasis
Orit Matcovitch-Natan et al.
SCIENCE (2016)
Specification of tissue-resident macrophages during organogenesis
Elvira Mass et al.
SCIENCE (2016)
Microglia contribute to circuit defects in Mecp2 null mice independent of microglia-specific loss of Mecp2 expression
Dorothy P. Schafer et al.
ELIFE (2016)
TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer's Disease Model
Yaming Wang et al.
CELL (2015)
Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System
Julia Bruttger et al.
IMMUNITY (2015)
Most Tissue-Resident Macrophages Except Microglia Are Derived from Fetal Hematopoietic Stem Cells
Jianpeng Sheng et al.
IMMUNITY (2015)
The Cytokine GM-CSF Drives the Inflammatory Signature of CCR2+ Monocytes and Licenses Autoimmunity
Andrew L. Croxford et al.
IMMUNITY (2015)
C-Myb+ Erythro-Myeloid Progenitor-Derived Fetal Monocytes Give Rise to Adult Tissue-Resident Macrophages
Guillaume Hoeffel et al.
IMMUNITY (2015)
Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors
Elisa Gomez Perdiguero et al.
NATURE (2015)
Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment
Yonit Lavin et al.
CELL (2014)
Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities
David Gosselin et al.
CELL (2014)
Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice
Calum C. Bain et al.
NATURE IMMUNOLOGY (2014)
Identification of a unique TGF-β dependent molecular and functional signature in microglia
Oleg Butovsky et al.
NATURE NEUROSCIENCE (2014)
Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain
Monica R. P. Elmore et al.
NEURON (2014)
Outcomes of transplantation using various hematopoietic cell sources in children with Hurler syndrome after myeloablative conditioning
Jaap Jan Boelens et al.
BLOOD (2013)
Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor
Christopher N. Parkhurst et al.
CELL (2013)
Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis
Simon Yona et al.
IMMUNITY (2013)
Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes
Daigo Hashimoto et al.
IMMUNITY (2013)
Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival
Jian Luo et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
A case of hereditary diffuse leukoencephalopathy with axonal spheroids caused by a de novo mutation in CSF1R masquerading as primary progressive multiple sclerosis
Ban-yu Saitoh et al.
MULTIPLE SCLEROSIS JOURNAL (2013)
Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways
Katrin Kierdorf et al.
NATURE NEUROSCIENCE (2013)
The microglial sensome revealed by direct RNA sequencing
Suzanne E. Hickman et al.
NATURE NEUROSCIENCE (2013)
Variant of TREM2 Associated with the Risk of Alzheimer's Disease
Thorlakur Jonsson et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
TREM2 Variants in Alzheimer's Disease
Rita Guerreiro et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages
Guillaume Hoeffel et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
The Fractalkine Receptor but Not CCR2 Is Present on Microglia from Embryonic Development throughout Adulthood
Makiko Mizutani et al.
JOURNAL OF IMMUNOLOGY (2012)
Wild-type microglia arrest pathology in a mouse model of Rett syndrome
Noel C. Derecki et al.
NATURE (2012)
Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis
Kazuhiro Maeda et al.
NATURE MEDICINE (2012)
Brain conditioning is instrumental for successful microglia reconstitution following hematopoietic stem cell transplantation
Alessia Capotondo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Microglial repopulation model reveals a robust homeostatic process for replacing CNS myeloid cells
Nicholas H. Varvel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells
Christian Schulz et al.
SCIENCE (2012)
All Hematopoietic Cells Develop from Hematopoietic Stem Cells through Flk2/Flt3-Positive Progenitor Cells
Scott W. Boyer et al.
CELL STEM CELL (2011)
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
Paul Hollingworth et al.
NATURE GENETICS (2011)
Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool
Bahareh Ajami et al.
NATURE NEUROSCIENCE (2011)
Hematopoietic Origin of Pathological Grooming in Hoxb8 Mutant Mice
Shau-Kwaun Chen et al.
CELL (2010)
The Contribution of the Tie2+ Lineage to Primitive and Definitive Hematopoietic Cells
Yuefeng Tang et al.
GENESIS (2010)
Hoxb8-Cre Mice: A Tool for Brain-Sparing Conditional Gene Deletion
Robert Witschi et al.
GENESIS (2010)
Selective Chemokine Receptor Usage by Central Nervous System Myeloid Cells in CCR2-Red Fluorescent Protein Knock-In Mice
Noah Saederup et al.
PLOS ONE (2010)
Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
Florent Ginhoux et al.
SCIENCE (2010)
Hematopoietic Stem Cell Gene Therapy with a Lentiviral Vector in X-Linked Adrenoleukodystrophy
Nathalie Cartier et al.
SCIENCE (2009)
Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions
Alexander Mildner et al.
NATURE NEUROSCIENCE (2007)
Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
Bahareh Ajami et al.
NATURE NEUROSCIENCE (2007)
Survival analysis of haematopoietic cell transplantation for childhood cerebral X-linked adrenoleukodystrophy: a comparison study
Asif Mahmood et al.
LANCET NEUROLOGY (2007)
Cell tracing shows the contribution of the yolk sac to adult haematopoiesis
Igor M. Samokhvalov et al.
NATURE (2007)
The P2Y12 receptor regulates microglial activation by extracellular nucleotides
Sharon E. Haynes et al.
NATURE NEUROSCIENCE (2006)
Gene therapy of metachromatic leukodystrophy reverses neurological damage and deficits mice
Alessandra Biffi et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Control of microglial neurotoxicity by the fractalkine receptor
Astrid E. Cardona et al.
NATURE NEUROSCIENCE (2006)
Cerebral X-linked adrenoleukodystrophy: the international hematopoietic cell transplantation experience from 1982 to 1999
C Peters et al.
BLOOD (2004)
vavCre transgenic mice:: A tool for mutagenesis in hematopoietic and endothelial lineages
P Georgiades et al.
GENESIS (2002)
Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects
XM Dai et al.
BLOOD (2002)
Long-term effect of bone-marrow transplantation for childhood-onset cerebral X-linked adrenoleukodystrophy
E Shapiro et al.
LANCET (2000)