期刊
NATURE NEUROSCIENCE
卷 23, 期 2, 页码 271-+出版社
NATURE PORTFOLIO
DOI: 10.1038/s41593-019-0575-0
关键词
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资金
- Intramural Research Program of the NIH, NINDS [ZIA NS003041]
- Neurophysiology Imaging Facility Core (NIMH, NINDS, NEI) [ZIC MH002899]
- International Neuroinformatics Coordinating Facility Seed Funding Grant
- NATIONAL INSTITUTE OF MENTAL HEALTH [ZICMH002899, ZIAMH002896] Funding Source: NIH RePORTER
While the fundamental importance of the white matter in supporting neuronal communication is well known, existing publications of primate brains do not feature a detailed description of its complex anatomy. The main barrier to achieving this is that existing primate neuroimaging data have insufficient spatial resolution to resolve white matter pathways fully. Here we present a resource that allows detailed descriptions of white matter structures and trajectories of fiber pathways in the marmoset brain. The resource includes: (1) the highest-resolution diffusion-weighted MRI data available to date, which reveal white matter features not previously described; (2) a comprehensive three-dimensional white matter atlas depicting fiber pathways that were either omitted or misidentified in previous atlases; and (3) comprehensive fiber pathway maps of cortical connections combining diffusion-weighted MRI tractography and neuronal tracing data. The resource, which can be downloaded from , will facilitate studies of brain connectivity and the development of tractography algorithms in the primate brain.
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