期刊
NATURE BIOTECHNOLOGY
卷 37, 期 12, 页码 1513-+出版社
NATURE PORTFOLIO
DOI: 10.1038/s41587-019-0328-3
关键词
-
资金
- National Natural Science Foundation of China [41922053, 41671248]
- National Key Basic Research Program of China [2015CB150503]
- National Key Research and Development Program of China [2018YFD1000800]
- 111 project [B12009]
- Netherlands Organization for Scientific Research (NWO) [ALW.870.15.050]
- Wellcome Trust through the Center for Chronic Diseases and Disorders (C2D2) [105624]
- Royal Society at the University of York [RSG\R1\180213, CHL\R1\180031]
Bacteriophages have been proposed as an alternative to pesticides to kill bacterial pathogens of crops. However, the efficacy of phage biocontrol is variable and poorly understood in natural rhizosphere microbiomes. We studied biocontrol efficacy of different phage combinations on Ralstonia solanacearum infection in tomato. Increasing the number of phages in combinations decreased the incidence of disease by up to 80% in greenhouse and field experiments during a single crop season. The decreased incidence of disease was explained by a reduction in pathogen density and the selection for phage-resistant but slow-growing pathogen strains, together with enrichment for bacterial species that were antagonistic toward R. solanacearum. Phage treatment did not affect the existing rhizosphere microbiota. Specific phage combinations have potential as precision tools to control plant pathogenic bacteria.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据