4.4 Article

Hesperozygis ringens (Benth.) Epling: a study involving extraction, chemical profiling, antioxidant and biological activity

期刊

NATURAL PRODUCT RESEARCH
卷 35, 期 22, 页码 4709-4714

出版社

TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2019.1710703

关键词

Hesperozygis ringens; ultrasound-assisted extraction; supercritical fluid extraction; antioxidant; cytotoxicity; genotoxicity

资金

  1. Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior

向作者/读者索取更多资源

This study aimed to determine the chemical markers of Hesperozygis ringens extracts obtained via different extraction methods and evaluated their biological activities. Results showed that the ultrasound-assisted extract exhibited higher antioxidant activity, and both extracts showed no cytotoxicity or genotoxicity against human mononuclear blood cells.
Hesperozygis ringens is a plant of the Lamiaceae family which is restricted to the Southern region of Brazil. It is popularly used as an insecticide, but knowledge on it is very scarce. This study aimed to determine the chemical markers of H. ringens extracts obtained via ultrasound-assisted (UAE-EtOH) and supercritical fluid (SFE-CO2) extractions. UAE-EtOH and SFE-CO2 extracts were characterised by UPLC-MS and GC-MS, respectively. Both products had their antioxidant activity, cytotoxicity and genotoxicity evaluated. Twelve compounds were found in the UAE-EtOH extract, including phenolic acids and flavonoids; the SFE-CO2 extract contained terpenes and phytosterols. The UAE-EtOH extract showed a greater antioxidant activity. Neither extract presented cytotoxicity or genotoxicity against human mononuclear blood cells.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.4
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据