期刊
MOLECULES
卷 25, 期 5, 页码 -出版社
MDPI
DOI: 10.3390/molecules25051043
关键词
gelatin fibers; electrospinning; ZnO; GO; antibacterial activity; wound dressing
资金
- State Natural Sciences Fund, China [21506236, 51372276]
- Research and Application of Gelatin Green Manufacturing 2.0 Technology by Enzymatic method [KFJ-STS-ZDTP-016]
- Hangzhou Research Institute of Technical Institute of Physics and Chemistry, CAS Fund [2016050201, 2016050202]
Current wound dressings have poor antimicrobial activities and are difficult to degrade. Therefore, biodegradable and antibacterial dressings are urgently needed. In this article, we used the hydrothermal method and side-by-side electrospinning technology to prepare a gelatin mat with incorporated zinc oxide/graphene oxide (ZnO/GO) nanocomposites. The resultant fibers were characterized by field emission environment scanning electron microscopy (FESEM), energy-dispersive X-ray spectroscopy (EDX), X-ray diffractometry (XRD) and Fourier transform infrared spectroscopy (FTIR). Results indicated that the gelatin fibers had good morphology, and ZnO/GO nanocomposites were uniformly dispersed on the fibers. The loss of Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) viability were observed to more than 90% with the incorporation of ZnO/GO. The degradation process showed that the composite fibers completely degraded within 7 days and had good controllable degradation characteristics. This study demonstrated the potential applicability of ZnO/GO-gelatin mats with excellent antibacterial properties as wound dressing material.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据