期刊
MOLECULES
卷 25, 期 2, 页码 -出版社
MDPI
DOI: 10.3390/molecules25020306
关键词
nitrogen-doped carbon dots; multicolor illumination; multicolor cell nuclear imaging; mitosis
The nitrogen-doped carbon dots (N-CQDs) were synthesized by citric acid as a raw material and propylene diamine as a passivation agent. Structure, optical properties and biocompatibility of N-CQDs were analyzed. It was found that the N-CQDs possessed concentration-dependent, multicolor photoluminescence and low toxicity. As demonstrated in the imaging of bioluminescence, by adjusting the concentration of N-CQDs, the cell imaging effect can be adjusted. The internalized N-CQDs were concentrated in the nucleus. A novel tool for studying the nuclear changes during the cell cycle was developed.
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