期刊
MOLECULES
卷 24, 期 24, 页码 -出版社
MDPI
DOI: 10.3390/molecules24244469
关键词
natural products; phenylpropanoids; phenolic acids; plants; depression; behavioral disorders; forced swim test; tail suspension test
资金
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)
- Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)
Depression is a health problem that compromises the quality of life of the world ' s population. It has different levels of severity and a symptomatic profile that affects social life and performance in work activities, as well as a high number of deaths in certain age groups. In the search for new therapeutic options for the treatment of this behavioral disorder, the present review describes studies on antidepressant activity of cinnamic acids, which are natural products found in medicinal plants and foods. The description of the animal models used and the mechanisms of action of these compounds are discussed.
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