4.6 Review

Recent Advances in the Discovery of CK2 Allosteric Inhibitors: From Traditional Screening to Structure-Based Design

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Design, synthesis and biological evaluation of new embelin derivatives as CK2 inhibitors

Sandra Oramas-Royo et al.

BIOORGANIC CHEMISTRY (2020)

Article Chemistry, Medicinal

Allosteric Modulator Discovery: From Serendipity to Structure-Based Design

Shaoyong Lu et al.

JOURNAL OF MEDICINAL CHEMISTRY (2019)

Review Chemistry, Medicinal

Small molecule modulators targeting protein kinase CK1 and CK2

Yuting Qiao et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)

Article Multidisciplinary Sciences

Discovery of holoenzyme-disrupting chemicals as substrate-selective CK2 inhibitors

Irina Kufareva et al.

SCIENTIFIC REPORTS (2019)

Article Chemistry, Medicinal

Structure-based Discovery of Novel CK2α-Binding Cyclic Peptides with Anti-cancer Activity

Shan Tang et al.

MOLECULAR INFORMATICS (2019)

Article Biochemistry & Molecular Biology

Novel non-ATP competitive small molecules targeting the CK2 α/β interface

Paul Brear et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2018)

Article Chemistry, Multidisciplinary

Second-generation CK2α inhibitors targeting the αD pocket

Jessica Iegre et al.

CHEMICAL SCIENCE (2018)

Article Chemistry, Multidisciplinary

A novel allosteric site in casein kinase 2α discovered using combining bioinformatics and biochemistry methods

Hai-ming Jiang et al.

ACTA PHARMACOLOGICA SINICA (2017)

Article Biochemistry & Molecular Biology

A fragment-based approach leading to the discovery of a novel binding site and the selective CK2 inhibitor CAM4066

Claudia De Fusco et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2017)

Review Chemistry, Medicinal

CK2 in Cancer: Cellular and Biochemical Mechanisms and Potential Therapeutic Target

Melissa M. J. Chua et al.

PHARMACEUTICALS (2017)

Review Oncology

Cell cycle proteins as promising targets in cancer therapy

Tobias Otto et al.

NATURE REVIEWS CANCER (2017)

Review Pharmacology & Pharmacy

Casein kinases as potential therapeutic targets

Giorgio Cozza et al.

EXPERT OPINION ON THERAPEUTIC TARGETS (2016)

Review Chemistry, Multidisciplinary

Emerging Computational Methods for the Rational Discovery of Allosteric Drugs

Jeffrey R. Wagner et al.

CHEMICAL REVIEWS (2016)

Article Chemistry, Multidisciplinary

Specific inhibition of CK2 alpha from an anchor outside the active site

Paul Brear et al.

CHEMICAL SCIENCE (2016)

Review Biochemistry & Molecular Biology

Protein kinase CK2 in breast cancer: the CK2β regulatory subunit takes center stage in epithelial plasticity

Odile Filhol et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2015)

Review Pharmacology & Pharmacy

Allosteric small-molecule kinase inhibitors

Peng Wu et al.

PHARMACOLOGY & THERAPEUTICS (2015)

Review Pharmacology & Pharmacy

Drugs for Allosteric Sites on Receptors

Cody J. Wenthur et al.

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 54 (2014)

Article Biochemistry & Molecular Biology

First Structure of Protein Kinase CK2 Catalytic Subunit with an Effective CK2β-Competitive Ligand

Jennifer Raaf et al.

ACS CHEMICAL BIOLOGY (2013)

Review Biochemistry & Molecular Biology

The Dark Side of Protein Kinase CK2 Inhibition

G. Cozza et al.

CURRENT MEDICINAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

Structure-based discovery of small molecules targeting different surfaces of protein-kinase CK2

Renaud Prudent et al.

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2010)

Review Biochemistry & Molecular Biology

New Protein Kinase CK2 Inhibitors: Jumping out of the Catalytic Box

Renaud Prudent et al.

CHEMISTRY & BIOLOGY (2009)

Article Biochemistry & Molecular Biology

The CK2α/CK2β interface of human protein kinase CK2 harbors a binding pocket for small molecules

Jennifer Raaf et al.

CHEMISTRY & BIOLOGY (2008)

Article Cell Biology

Identification of chemical inhibitors of protein-kinase CK2 subunit interaction

Beatrice Laudet et al.

MOLECULAR AND CELLULAR BIOCHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Structure-based design of small peptide inhibitors of protein kinase CK2 subunit interaction

Beatrice Laudet et al.

BIOCHEMICAL JOURNAL (2007)