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Crystal structure of the Bcl-XL-beclin 1 peptide complex -: Beclin 1 is a novel BH3-only protein
Adam Oberstein et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
The crystal structure of Atg3, an autophagy-related ubiquitin carrier protein (E2) enzyme that mediates Atg8 lipidation
Yuya Yamada et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Structure of Atg5•Atg16, a complex essential for autophagy
Minako Matsushita et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Hierarchy of Atg proteins in pre-autophagosomal structure organization
Kuninori Suzuki et al.
GENES TO CELLS (2007)
Metabolic catastrophe as a means to cancer cell death
Shengkan Jin et al.
JOURNAL OF CELL SCIENCE (2007)
Role of autophagy in cancer - Management of metabolic stress
Shengkan Jin et al.
AUTOPHAGY (2007)
Lysosomal turnover of GABARAP-phospholipid conjugate is activated during differentiation of C2C12 cells to myotubes without inactivation of the mTor kinase-signaling pathway
Isei Tanida et al.
AUTOPHAGY (2006)
Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes
Andrew R. J. Young et al.
JOURNAL OF CELL SCIENCE (2006)
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
Kurt Degenhardt et al.
CANCER CELL (2006)
Atg8L/APg8L is the fourth mammalian modifier of mammalian Atg8 conjugation mediated by human Atg4B, Atg7 and Atg3
Isei Tanida et al.
FEBS JOURNAL (2006)
Assortment of phosphatidylinositol 3-kinase complexes-Atg14p directs association of complex I to the pre-autophagosomal structure in Saccharomyces cerevisiae
K Obara et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
Autophagic programmed cell death by selective catalase degradation
L Yu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Cytosolic overexpression of p62 sequestosome 1 in neoplastic prostate tissue
H Kitamura et al.
HISTOPATHOLOGY (2006)
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
G Bjorkoy et al.
JOURNAL OF CELL BIOLOGY (2005)
The pleiotropic role of autophagy: from protein metabolism to bactericide
N Mizushima
CELL DEATH AND DIFFERENTIATION (2005)
The diversity expression of p62 in digestive system cancers
YX Su et al.
CLINICAL IMMUNOLOGY (2005)
Atg9 cycles between mitochondria and the pre-autophagosomal structure in yeasts
Fulvio Reggiori et al.
AUTOPHAGY (2005)
Endothelial nitric-oxide synthase antisense (NOS3AS) gene encodes an autophagy-related protein (APG9-like2) highly expressed in trophoblast
T Yamada et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy
Y Kabeya et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors
H Takeuchi et al.
CANCER RESEARCH (2005)
The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function
Norihiko Furuya et al.
AUTOPHAGY (2005)
Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3
T Kanzawa et al.
ONCOGENE (2005)
Growth factor regulation of autophagy and cell survival in the absence of apoptosis
JJ Lum et al.
CELL (2005)
The role of autophagy in cancer development and response to therapy
Y Kondo et al.
NATURE REVIEWS CANCER (2005)
Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1
F Scarlatti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Development by self-digestion: Molecular mechanisms and biological functions of autophagy
B Levine et al.
DEVELOPMENTAL CELL (2004)
Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells
T Kanzawa et al.
CELL DEATH AND DIFFERENTIATION (2004)
Resveratrol-induced autophagocytosis in ovarian cancer cells
AW Opipari et al.
CANCER RESEARCH (2004)
The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure
F Reggiori et al.
DEVELOPMENTAL CELL (2004)
Death by design: apoptosis, necrosis and autophagy
AL Edinger et al.
CURRENT OPINION IN CELL BIOLOGY (2004)
Human light chain 3/MAP1LC3B is cleaved at its carboxyl-terminal Met121 to expose Gly120 for lipidation and targeting to autophagosomal membranes
I Tanida et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Autophagy in health and disease: A double-edged sword
T Shintani et al.
SCIENCE (2004)
LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation
Y Kabeya et al.
JOURNAL OF CELL SCIENCE (2004)
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
ZY Yue et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
A unified nomenclature for yeast autophagy-related genes
DJ Klionsky et al.
DEVELOPMENTAL CELL (2003)
Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B
H He et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate
N Mizushima et al.
JOURNAL OF CELL SCIENCE (2003)
p62 overexpression in breast tumors and regulation by prostate-derived Ets factor in breast cancer cells
HGR Thompson et al.
ONCOGENE (2003)
Molecular response of human glioblastoma multiforme cells to ionizing radiation: cell cycle arrest, modulation of the expression of cyclin-dependent kinase inhibitors, and autophagy
KC Yao et al.
JOURNAL OF NEUROSURGERY (2003)
GATE-16 and GABARAP are authentic modifiers mediated by Apg7 and Apg3
I Tanida et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Retromer function in endosome-to-Golgi retrograde transport is regulated by the yeast Vps34 PtdIns 3-kinase
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JOURNAL OF CELL SCIENCE (2002)
Formation of the ∼350-kDa Apg12-Apg5•Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast
A Kuma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p
I Tanida et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation
K Suzuki et al.
EMBO JOURNAL (2001)
Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae
A Kihara et al.
JOURNAL OF CELL BIOLOGY (2001)
The human homolog of Saccharomyces cerevisiae Apg7p is a protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3
I Tanida et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
A ubiquitin-like system mediates protein lipidation
Y Ichimura et al.
NATURE (2000)
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
Y Kabeya et al.
EMBO JOURNAL (2000)
The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway
T Kirisako et al.
JOURNAL OF CELL BIOLOGY (2000)
Tor-mediated induction of autophagy via an Apg1 protein kinase complex
Y Kamada et al.
JOURNAL OF CELL BIOLOGY (2000)
The itinerary of a vesicle component, Aut7p/Cvt5p, terminates in the yeast vacuole via the autophagy/Cvt pathways
WP Huang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Apg9p/Cvt7p is an integral membrane protein required for transport vesicle formation in the Cvt and autophagy pathways
T Noda et al.
JOURNAL OF CELL BIOLOGY (2000)
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