期刊
MITOCHONDRION
卷 50, 期 -, 页码 121-131出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.mito.2019.10.003
关键词
Mitochondria; Proteostasis; Quality control; Proteases; Chaperones; Mitophagy; Aggregates
资金
- Swedish Research Council
- Knut and Alice Wallenberg Foundation
- Austrian Science Fund FWF [P27183-B24]
- Austrian Science Fund (FWF) [P27183] Funding Source: Austrian Science Fund (FWF)
Mitochondria play pivotal roles in cellular energy metabolism, the synthesis of essential biomolecules and the regulation of cell death and aging. The proper folding, unfolding and degradation of the many proteins active within mitochondria is surveyed by the mitochondrial quality control machineries. Here, we describe the principal components of the mitochondrial quality control system and recent developments in the elucidation of the molecular mechanisms maintaining a functional mitochondrial proteome.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据