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C. Munoz-Pinedo et al.
CELL DEATH & DISEASE (2014)
The autophagy regulators Ambra1 and Beclin 1 are required for adult neurogenesis in the brain subventricular zone
M. Yazdankhah et al.
CELL DEATH & DISEASE (2014)
Natural small-molecule enhancers of autophagy induce autophagic cell death in apoptosis-defective cells
Betty Yuen Kwan Law et al.
SCIENTIFIC REPORTS (2014)
Dnase2a Deficiency Uncovers Lysosomal Clearance of Damaged Nuclear DNA via Autophagy
Yuk Yuen Lan et al.
CELL REPORTS (2014)
Autophagy and Its Effects: Making Sense of Double-Edged Swords
Andrew Thorburn
PLOS BIOLOGY (2014)
Atg6/UVRAG/Vps34-Containing Lipid Kinase Complex Is Required for Receptor Downregulation through Endolysosomal Degradation and Epithelial Polarity during Drosophila Wing Developmentd
Peter Lorincz et al.
BIOMED RESEARCH INTERNATIONAL (2014)
Selective autophagy of non-ubiquitylated targets in plants: looking for cognate receptor/adaptor proteins
Vasko Veljanovski et al.
FRONTIERS IN PLANT SCIENCE (2014)
The intricacy of nuclear membrane dynamics during nucleophagy
Dalibor Mijaljica et al.
Nucleus (2014)
Variants of mitochondrial autophagy: Types 1 and 2 mitophagy and micromitophagy (Type 3)
John J. Lemasters
REDOX BIOLOGY (2014)
The Importance of Autophagy in Cardioprotection
Sebastiano Sciarretta et al.
HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION (2014)
Adaptive changes in autophagy after UPS impairment in Parkinson's disease
Yu-fei Shen et al.
ACTA PHARMACOLOGICA SINICA (2013)
Why should autophagic flux be assessed?
Xiao-jie Zhang et al.
ACTA PHARMACOLOGICA SINICA (2013)
Molecular Chaperone Functions in Protein Folding and Proteostasis
Yujin E. Kim et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 82 (2013)
Type I interferons induce autophagy in certain human cancer cell lines
Hana Schmeisser et al.
AUTOPHAGY (2013)
Akt/mTOR signalling in myelination
Camilla Norrmen et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2013)
A novel mechanism of XIAP degradation induced by timosaponin AIII in hepatocellular carcinoma
Ning Wang et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
Inhibition of LRRK2 kinase activity stimulates macroautophagy
Claudia Manzoni et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
Benzyl isothiocyanate induces protective autophagy in human prostate cancer cells via inhibition of mTOR signaling
Ji-Fan Lin et al.
CARCINOGENESIS (2013)
Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway
Dong-Mei Zhang et al.
CARCINOGENESIS (2013)
Cardiomyocyte ryanodine receptor degradation by chaperone-mediated autophagy
Zully Pedrozo et al.
CARDIOVASCULAR RESEARCH (2013)
TLR2-dependent selective autophagy regulates NF-κB lysosomal degradation in hepatoma-derived M2 macrophage differentiation
C-P Chang et al.
CELL DEATH AND DIFFERENTIATION (2013)
Selective autophagy in budding yeast
Kuninori Suzuki
CELL DEATH AND DIFFERENTIATION (2013)
Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion
Jing Zhou et al.
CELL RESEARCH (2013)
Autophagy negatively regulates cancer cell proliferation via selectively targeting VPRBP
Bo-Shi Wang et al.
CLINICAL SCIENCE (2013)
Atg6 is required for multiple vesicle trafficking pathways and hematopoiesis in Drosophila
Bhupendra V. Shravage et al.
DEVELOPMENT (2013)
Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalk
Katy J. Petherick et al.
EMBO JOURNAL (2013)
Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury
Ikuko Maejima et al.
EMBO JOURNAL (2013)
Autophagy and ageing: implications for age-related neurodegenerative diseases
Bernadette Carroll et al.
AUTOPHAGY: MOLECULES AND MECHANISMS (2013)
Piperine inhibits the proliferation of human prostate cancer cells via induction of cell cycle arrest and autophagy
Dong-yun Ouyang et al.
FOOD AND CHEMICAL TOXICOLOGY (2013)
Chaperone-mediated autophagy degrades mutant p53
Helin Vakifahmetoglu-Norberg et al.
GENES & DEVELOPMENT (2013)
Autophagic Processes in Yeast: Mechanism, Machinery and Regulation
Fulvio Reggiori et al.
GENETICS (2013)
Autophagy and inflammatory diseases
Sarah A. Jones et al.
IMMUNOLOGY AND CELL BIOLOGY (2013)
Palmitate induces autophagy in pancreatic β-cells via endoplasmic reticulum stress and its downstream JNK pathway
Ying-Ying Chen et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2013)
Deletion of Autophagy-related 5 (Atg5) and Pik3c3 Genes in the Lens Causes Cataract Independent of Programmed Organelle Degradation
Hideaki Morishita et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Chaperone-mediated Autophagy Targets Hypoxia-inducible Factor-1α (HIF-1α) for Lysosomal Degradation
Maimon E. Hubbi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Nucleophagy at a glance
Dalibor Mijaljica et al.
JOURNAL OF CELL SCIENCE (2013)
Enhanced autophagy ameliorates cardiac proteinopathy
Md. Shenuarin Bhuiyan et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction
Hilaire C. Lam et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells
Zhen Yang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
Elevated autophagic sequestration of mitochondria and lipid droplets in steatotic hepatocytes of chronic ethanol-treated rats: an immunohistochemical and electron microscopic study
Nabil Eid et al.
JOURNAL OF MOLECULAR HISTOLOGY (2013)
Ursolic acid induces cell death and modulates autophagy through JNK pathway in apoptosis-resistant colorectal cancer cells
Cristina P. R. Xavier et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2013)
Autophagy Negatively Regulates Early Axon Growth in Cortical Neurons
Byung-Kwan Ban et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
Exercise-induced AMPK activity in skeletal muscle: Role in glucose uptake and insulin sensitivity
Martin Friedrichsen et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2013)
Regulation of ER-phagy by a Ypt/Rab GTPase module
Zhanna Lipatova et al.
MOLECULAR BIOLOGY OF THE CELL (2013)
Neuroprotective effect of brain-derived neurotrophic factor mediated by autophagy through the PI3K/Akt/mTOR pathway
Ai Chen et al.
MOLECULAR MEDICINE REPORTS (2013)
The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy
Jens Fullgrabe et al.
NATURE (2013)
Identification of a candidate therapeutic autophagy-inducing peptide
Sanae Shoji-Kawata et al.
NATURE (2013)
ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase
Ryan C. Russell et al.
NATURE CELL BIOLOGY (2013)
Autophagy regulates endothelial cell processing, maturation and secretion of von Willebrand factor
Takehiro Torisu et al.
NATURE MEDICINE (2013)
Interplay of LRRK2 with chaperone-mediated autophagy
Samantha J. Orenstein et al.
NATURE NEUROSCIENCE (2013)
Excitatory/Inhibitory Synaptic Imbalance Leads to Hippocampal Hyperexcitability in Mouse Models of Tuberous Sclerosis
Helen S. Bateup et al.
NEURON (2013)
Autophagy Activation Clears ELAVL1/HuR-Mediated Accumulation of SQSTM1/p62 during Proteasomal Inhibition in Human Retinal Pigment Epithelial Cells
Johanna Viiri et al.
PLOS ONE (2013)
TLR-induced PAI-2 expression suppresses IL-1β processing via increasing autophagy and NLRP3 degradation
Shih-Yi Chuang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy
Yuan Tian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Skeletal muscle autophagy: a new metabolic regulator
Brian A. Neel et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2013)
Marchantin M: a novel inhibitor of proteasome induces autophagic cell death in prostate cancer cells
H. Jiang et al.
CELL DEATH & DISEASE (2013)
Spatiotemporally controlled induction of autophagy-mediated lysosome turnover
Yu-Hsien Hung et al.
NATURE COMMUNICATIONS (2013)
Mahogunin ring finger-1 (MGRN1) Suppresses Chaperone-Associated Misfolded Protein Aggregation and Toxicity
Deepak Chhangani et al.
SCIENTIFIC REPORTS (2013)
Neuronal Autophagy and Neurodevelopmental Disorders
Kyung-Min Lee et al.
Experimental Neurobiology (2013)
Autophagy in infection, inflammation and immunity
Vojo Deretic et al.
NATURE REVIEWS IMMUNOLOGY (2013)
Cross talk between NADPH oxidase and autophagy in pulmonary artery endothelial cells with intrauterine persistent pulmonary hypertension
Ru-Jeng Teng et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2012)
Autophagy as a Stress-Response and Quality-Control Mechanism: Implications for Cell Injury and Human Disease
Lyndsay Murrow et al.
Annual Review of Pathology-Mechanisms of Disease (2012)
Pharmacological ascorbate induces cytotoxicity in prostate cancer cells through ATP depletion and induction of autophagy
Ping Chen et al.
ANTI-CANCER DRUGS (2012)
Transition From Obesity to Metabolic Syndrome Is Associated With Altered Myocardial Autophagy and Apoptosis
Zi-Lun Li et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2012)
Impaired autophagy contributes to muscle atrophy in glycogen storage disease type II patients
Anna Chiara Nascimbeni et al.
AUTOPHAGY (2012)
Autophagy defects in Lafora disease Cause or consequence?
Rajat Puri et al.
AUTOPHAGY (2012)
Isorhynchophylline, a natural alkaloid, promotes the degradation of alpha-synuclein in neuronal cells via inducing autophagy
Jia-Hong Lu et al.
AUTOPHAGY (2012)
The fibroblast growth factor signaling axis controls cardiac stem cell differentiation through regulating autophagy
Jue Zhang et al.
AUTOPHAGY (2012)
Atg5 and Ambra1 differentially modulate neurogenesis in neural stem cells
Patricia Vazquez et al.
AUTOPHAGY (2012)
Rottlerin induces autophagy which leads to apoptotic cell death through inhibition of PI3K/Akt/mTOR pathway in human pancreatic cancer stem cells
Brahma N. Singh et al.
BIOCHEMICAL PHARMACOLOGY (2012)
MG-2477, a new tubulin inhibitor, induces autophagy through inhibition of the Akt/mTOR pathway and delayed apoptosis in A549 cells
Giampietro Viola et al.
BIOCHEMICAL PHARMACOLOGY (2012)
Mitophagy: mechanisms, pathophysiological roles, and analysis
Wen-Xing Ding et al.
BIOLOGICAL CHEMISTRY (2012)
Autophagic degradation of the BCR-ABL oncoprotein and generation of antileukemic responses by arsenic trioxide
Dennis J. Goussetis et al.
BLOOD (2012)
Autophagy Dysregulation in Amyotrophic Lateral Sclerosis
Sheng Chen et al.
BRAIN PATHOLOGY (2012)
Erufosine simultaneously induces apoptosis and autophagy by modulating the Akt-mTOR signaling pathway in oral squamous cell carcinoma
Vaishali Kapoor et al.
CANCER LETTERS (2012)
Macrophage Autophagy Plays a Protective Role in Advanced Atherosclerosis
Xianghai Liao et al.
CELL METABOLISM (2012)
Microautophagy: lesser-known self-eating
Wen-wen Li et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2012)
Autophagy as an innate immunity paradigm: expanding the scope and repertoire of pattern recognition receptors
Vojo Deretic
CURRENT OPINION IN IMMUNOLOGY (2012)
Neuronal autophagy and neurodegenerative diseases
Jin H. Son et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2012)
Aspirin Inhibits mTOR Signaling, Activates AMP-Activated Protein Kinase, and Induces Autophagy in Colorectal Cancer Cells
Farhat V. N. Din et al.
GASTROENTEROLOGY (2012)
Altered mTOR signaling and enhanced CYFIP2 expression levels in subjects with fragile X syndrome
C. A. Hoeffer et al.
GENES BRAIN AND BEHAVIOR (2012)
Monascuspiloin Induces Apoptosis and Autophagic Cell Death in Human Prostate Cancer Cells via the Akt and AMPK Signaling Pathways
Rong-Jane Chen et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2012)
STAT1 deficiency in the heart protects against myocardial infarction by enhancing autophagy
J. McCormick et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2012)
What to Eat: Evidence for Selective Autophagy in Plants
Brice E. Floyd et al.
JOURNAL OF INTEGRATIVE PLANT BIOLOGY (2012)
Autophagy and disease: always two sides to a problem
Sunandini Sridhar et al.
JOURNAL OF PATHOLOGY (2012)
Autophagic targeting of Src promotes cancer cell survival following reduced FAK signallin
Emma Sandilands et al.
NATURE CELL BIOLOGY (2012)
Selective autophagy degrades DICER and AGO2 and regulates miRNA activity
Derrick Gibbings et al.
NATURE CELL BIOLOGY (2012)
Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
Chong-Shan Shi et al.
NATURE IMMUNOLOGY (2012)
Autophagic degradation of tau in primary neurons and its enhancement by trehalose
Ulrike Krueger et al.
NEUROBIOLOGY OF AGING (2012)
Neuroprotection of kaempferol by autophagy in models of rotenone-mediated acute toxicity: possible implications for Parkinson's disease
Giuseppe Filomeni et al.
NEUROBIOLOGY OF AGING (2012)
Chloroquine-Mediated Lysosomal Dysfunction Enhances the Anticancer Effect of Nutrient Deprivation
Ljubica Harhaji-Trajkovic et al.
PHARMACEUTICAL RESEARCH (2012)
Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency
Quentin McAfee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Keap1 degradation by autophagy for the maintenance of redox homeostasis
Keiko Taguchi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Variations on a theme: plant autophagy in comparison to yeast and mammals
Tamar Avin-Wittenberg et al.
PROTOPLASMA (2012)
Paget's Disease of Bone: Evidence for Complex Pathogenetic Interactions
Pui Yan Jenny Chung et al.
SEMINARS IN ARTHRITIS AND RHEUMATISM (2012)
Chaperone-mediated autophagy: a unique way to enter the lysosome world
Susmita Kaushik et al.
TRENDS IN CELL BIOLOGY (2012)
Autophagy in the regulation of pathogen replication and adaptive immunity
Felix Randow et al.
TRENDS IN IMMUNOLOGY (2012)
Anti-tumor immunity, autophagy and chemotherapy
Gyoergyi Muzes et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2012)
Autophagy as a new therapeutic target in Duchenne muscular dystrophy
C. De Palma et al.
CELL DEATH & DISEASE (2012)
The Role of Autophagy in Parkinson's Disease
Melinda A. Lynch-Day et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)
Intracellular Vesicle Acidification Promotes Maturation of Infectious Poliovirus Particles
Alexsia L. Richards et al.
PLOS PATHOGENS (2012)
Neuronal Autophagy: A Housekeeper or a Fighter in Neuronal Cell Survival?
Jin-A Lee
Experimental Neurobiology (2012)
α-synuclein, LRRK2 and their interplay in Parkinson's disease
Guoxiang Liu et al.
FUTURE NEUROLOGY (2012)
Complete Induction of Autophagy Is Essential for Cardioprotection in Sepsis
Chi-Hsun Hsieh et al.
ANNALS OF SURGERY (2011)
The Role of Atg Proteins in Autophagosome Formation
Noboru Mizushima et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 27 (2011)
DJ-1 regulation of mitochondrial function and autophagy through oxidative stress
Melissa K. McCoy et al.
AUTOPHAGY (2011)
Plant NBR1 is a selective autophagy substrate and a functional hybrid of the mammalian autophagic adapters NBR1 and p62/SQSTM1
Steingrim Svenning et al.
AUTOPHAGY (2011)
Quercetin induces protective autophagy in gastric cancer cells Involvement of Akt-mTOR- and hypoxia-induced factor 1α-mediated signaling
Kui Wang et al.
AUTOPHAGY (2011)
Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition
Shinji Saiki et al.
AUTOPHAGY (2011)
Microautophagy in mammalian cells Revisiting a 40-year-old conundrum
Dalibor Mijaljica et al.
AUTOPHAGY (2011)
Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway
Ljubica Vucicevic et al.
AUTOPHAGY (2011)
Conservation of Structural and Functional Elements of TSC1 and TSC2: A Bioinformatic Comparison Across Animal Models
Jaco Serfontein et al.
BEHAVIOR GENETICS (2011)
The serine/threonine kinase ULK1 is a target of multiple phosphorylation events
Markus Bach et al.
BIOCHEMICAL JOURNAL (2011)
SNARE Proteins Are Required for Macroautophagy
Usha Nair et al.
CELL (2011)
Autophagy: Renovation of Cells and Tissues
Noboru Mizushima et al.
CELL (2011)
Beclin1 Controls the Levels of p53 by Regulating the Deubiquitination Activity of USP10 and USP13
Junli Liu et al.
CELL (2011)
Eating the strangers within: host control of intracellular bacteria via xenophagy
Leigh A. Knodler et al.
CELLULAR MICROBIOLOGY (2011)
Shedding Light on Mammalian Microautophagy
Tomer Shpilka et al.
DEVELOPMENTAL CELL (2011)
Microautophagy of Cytosolic Proteins by Late Endosomes
Ranjit Sahu et al.
DEVELOPMENTAL CELL (2011)
BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins
Martin Gamerdinger et al.
EMBO REPORTS (2011)
Bufalin induces autophagy-mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation
Chuan-Ming Xie et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
Reduced AKT/mTOR signaling and protein synthesis dysregulation in a Rett syndrome animal model
Sara Ricciardi et al.
HUMAN MOLECULAR GENETICS (2011)
Lucanthone Is a Novel Inhibitor of Autophagy That Induces Cathepsin D-mediated Apoptosis
Jennifer S. Carew et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Mutant A53T α-Synuclein Induces Neuronal Death by Increasing Mitochondrial Autophagy
Vinay Choubey et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation
James Harris et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
p62/SQSTM1 in autophagic clearance of a non-ubiquitylated substrate
Yoshihisa Watanabe et al.
JOURNAL OF CELL SCIENCE (2011)
Azithromycin blocks autophagy and may predispose cystic fibrosis patients to mycobacterial infection
Maurizio Renna et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Autophagy in antigen-presenting cells results in presentation of citrullinated peptides to CD4 T cells
Jamie M. Ireland et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Autophagy Negatively Regulates Keratinocyte Inflammatory Responses via Scaffolding Protein p62/SQSTM1
Hye-Mi Lee et al.
JOURNAL OF IMMUNOLOGY (2011)
Autophagy in parasitic protists: Unique features and drug targets
Ana Brennand et al.
MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2011)
Serine 403 Phosphorylation of p62/SQSTM1 Regulates Selective Autophagic Clearance of Ubiquitinated Proteins
Gen Matsumoto et al.
MOLECULAR CELL (2011)
Acetylation Targets the M2 Isoform of Pyruvate Kinase for Degradation through Chaperone-Mediated Autophagy and Promotes Tumor Growth
Lei Lv et al.
MOLECULAR CELL (2011)
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
Joungmok Kim et al.
NATURE CELL BIOLOGY (2011)
Chemical modulators of autophagy as biological probes and potential therapeutics
Angeleen Fleming et al.
NATURE CHEMICAL BIOLOGY (2011)
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
Kiichi Nakahira et al.
NATURE IMMUNOLOGY (2011)
Dendritic spine pathology in neuropsychiatric disorders
Peter Penzes et al.
NATURE NEUROSCIENCE (2011)
Autophagy: ESCRTing proteins for microautophagy
Katharine H. Wrighton
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)
Synaptic dysfunction in genetic models of Parkinson's disease: A role for autophagy?
Edward D. Plowey et al.
NEUROBIOLOGY OF DISEASE (2011)
The ATG1/ATG13 Protein Kinase Complex Is Both a Regulator and a Target of Autophagic Recycling in Arabidopsis
Anongpat Suttangkakul et al.
PLANT CELL (2011)
Autophagy Interplay with Apoptosis and Cell Cycle Regulation in the Growth Inhibiting Effect of Resveratrol in Glioma Cells
Eduardo C. Filippi-Chiela et al.
PLOS ONE (2011)
Role of Chaperone Mediated Autophagy (CMA) in the Degradation of Misfolded N-CoR Protein in Non-Small Cell Lung Cancer (NSCLC) Cells
Azhar Bin Ali et al.
PLOS ONE (2011)
Neurofibromatosis-1 regulates mTOR-mediated astrocyte growth and glioma formation in a TSC/Rheb-independent manner
Sutapa Banerjee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Cellular Strategies of Protein Quality Control
Bryan Chen et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)
APP and APLP1 are degraded through autophagy in response to proteasome inhibition in neuronal cells
Fangfang Zhou et al.
PROTEIN & CELL (2011)
Glycogen Hyperphosphorylation Underlies Lafora Body Formation
Julie Turnbull et al.
ANNALS OF NEUROLOGY (2010)
Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer
Kevin N. Dalby et al.
AUTOPHAGY (2010)
Inhibition of autophagy in the heart induces age-related cardiomyopathy
Manabu Taneike et al.
AUTOPHAGY (2010)
Hispolon promotes MDM2 downregulation through chaperone-mediated autophagy
Te-Ling Lu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
LC3, a microtubule-associated protein1A/B light chain3, is involved in cytoplasmic lipid droplet formation
Masahiro Shibata et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Pineapple bromelain induces autophagy, facilitating apoptotic response in mammary carcinoma cells
Kulpreet Bhui et al.
BIOFACTORS (2010)
Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3
Fiona M. Menzies et al.
BRAIN (2010)
Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders
Jeffrey J. Hutsler et al.
BRAIN RESEARCH (2010)
C. elegans Screen Identifies Autophagy Genes Specific to Multicellular Organisms
Ye Tian et al.
CELL (2010)
Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations
Ju-Hyun Lee et al.
CELL (2010)
Mitochondria Supply Membranes for Autophagosome Biogenesis during Starvation
Dale W. Hailey et al.
CELL (2010)
FOXO/4E-BP Signaling in Drosophila Muscles Regulates Organism-wide Proteostasis during Aging
Fabio Demontis et al.
CELL (2010)
c-Abl and Arg tyrosine kinases regulate lysosomal degradation of the oncoprotein Galectin-3
X. Li et al.
CELL DEATH AND DIFFERENTIATION (2010)
Chaperone-Assisted Selective Autophagy Is Essential for Muscle Maintenance
Verena Arndt et al.
CURRENT BIOLOGY (2010)
The role of the Atg1/ULK1 complex in autophagy regulation
Noboru Mizushima
CURRENT OPINION IN CELL BIOLOGY (2010)
Mammalian autophagy: core molecular machinery and signaling regulation
Zhifen Yang et al.
CURRENT OPINION IN CELL BIOLOGY (2010)
Autophagic pathways and metabolic stress
S. Kaushik et al.
DIABETES OBESITY & METABOLISM (2010)
Autophagy in skeletal muscle
Marco Sandri
FEBS LETTERS (2010)
The Cvt pathway as a model for selective autophagy
Melinda A. Lynch-Day et al.
FEBS LETTERS (2010)
Laforin, the most common protein mutated in Lafora disease, regulates autophagy
Carmen Aguado et al.
HUMAN MOLECULAR GENETICS (2010)
The Bcl-2 Homology Domain 3 Mimetic Gossypol Induces Both Beclin 1-dependent and Beclin 1-independent Cytoprotective Autophagy in Cancer Cells
Ping Gao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Autophagy in Hypertensive Heart Disease
Zhao V. Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Regulation of the autophagy protein LC3 by phosphorylation
Salvatore J. Cherra et al.
JOURNAL OF CELL BIOLOGY (2010)
The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy
Sabrina Di Bartolomeo et al.
JOURNAL OF CELL BIOLOGY (2010)
An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis
Muriel Mari et al.
JOURNAL OF CELL BIOLOGY (2010)
Berberine Induces Autophagic Cell Death and Mitochondrial Apoptosis in Liver Cancer Cells: The Cellular Mechanism
Ning Wang et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2010)
Rapamycin Activates Autophagy and Improves Myelination in Explant Cultures from Neuropathic Mice
Sunitha Rangaraju et al.
JOURNAL OF NEUROSCIENCE (2010)
Dysregulation of mTOR Signaling in Fragile X Syndrome
Ali Sharma et al.
JOURNAL OF NEUROSCIENCE (2010)
Autophagy: cellular and molecular mechanisms
Danielle Glick et al.
JOURNAL OF PATHOLOGY (2010)
The Selective Macroautophagic Degradation of Aggregated Proteins Requires the PI3P-Binding Protein Alfy
Maria Filimonenko et al.
MOLECULAR CELL (2010)
Autophagy and the Integrated Stress Response
Guido Kroemer et al.
MOLECULAR CELL (2010)
mTOR Regulates the Invasive Properties of Synovial Fibroblasts in Rheumatoid Arthritis
Teresina Laragione et al.
MOLECULAR MEDICINE (2010)
Autophagy in viral replication and pathogenesis
Donna Sir et al.
MOLECULES AND CELLS (2010)
Autophagy in mammalian development and differentiation
Noboru Mizushima et al.
NATURE CELL BIOLOGY (2010)
Plasma membrane contributes to the formation of pre-autophagosomal structures
Brinda Ravikumar et al.
NATURE CELL BIOLOGY (2010)
Eaten alive: a history of macroautophagy
Zhifen Yang et al.
NATURE CELL BIOLOGY (2010)
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
Leonardo H. Travassos et al.
NATURE IMMUNOLOGY (2010)
Autophagy induced by valproic acid is associated with oxidative stress in glioma cell lines
Jun Fu et al.
NEURO-ONCOLOGY (2010)
Generation of Tau Aggregates and Clearance by Autophagy in an Inducible Cell Model of Tauopathy
Y. Wang et al.
NEURODEGENERATIVE DISEASES (2010)
Degradation of TDP-43 and its pathogenic form by autophagy and the ubiquitin-proteasome system
Xiaoju Wang et al.
NEUROSCIENCE LETTERS (2010)
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
Brinda Ravikumar et al.
PHYSIOLOGICAL REVIEWS (2010)
Dynein light chain 1 is required for autophagy, protein clearance, and cell death in Drosophila
Yakup Batlevi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema
Zhi-Hua Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Shaping Development of Autophagy Inhibitors with the Structure of the Lipid Kinase Vps34
Simon Miller et al.
SCIENCE (2010)
Autophagy and Metabolism
Joshua D. Rabinowitz et al.
SCIENCE (2010)
Chaperone-mediated autophagy: Molecular mechanisms and physiological relevance
Samantha J. Orenstein et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2010)
When autophagy meets viruses: a double-edged sword with functions in defense and offense
Hee Jin Kim et al.
SEMINARS IN IMMUNOPATHOLOGY (2010)
Chaperone-mediated autophagy: selectivity pays off
Ana Maria Cuervo
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2010)
Cytotoxicity of apigenin on leukemia cell lines: implications for prevention and therapy
R. R. Ruela-de-Sousa et al.
CELL DEATH & DISEASE (2010)
What is schizophrenia: A neurodevelopmental or neurodegenerative disorder or a combination of both? A critical analysis
Parmanand Kulhara et al.
Indian Journal of Psychiatry (2010)
Regulation Mechanisms and Signaling Pathways of Autophagy
Congcong He et al.
ANNUAL REVIEW OF GENETICS (2009)
Molecular mechanisms of oridonin-induced apoptosis and autophagy in murine fibrosarcoma L929 cells
Yan Cheng et al.
AUTOPHAGY (2009)
A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy
Carol A. Mercer et al.
AUTOPHAGY (2009)
Autophagy genes mediate the effect of calcineurin on life span in C. elegans
Meenakshi Dwivedi et al.
AUTOPHAGY (2009)
Safingol (L-threo-sphinganine) induces autophagy in solid tumor cells through inhibition of PKC and the PI3-kinase pathway
Jesse Coward et al.
AUTOPHAGY (2009)
Targeted deletion of autophogy-related 5 (atg5) impairs adipogenesis in a cellular model and in mice
Rebecca Baerga et al.
AUTOPHAGY (2009)
When more is less Excess and deficiency of autophagy coexist in skeletal muscle in Pompe disease
Nina Raben et al.
AUTOPHAGY (2009)
Autophagic degradation of nuclear components in mammalian cells
Young-Eun Park et al.
AUTOPHAGY (2009)
The autophagic pathway is a key component in the lysosomal dependent entry of Trypanosoma cruzi into the host cell
Patricia S. Romano et al.
AUTOPHAGY (2009)
Autophagy is involved in influenza A virus replication
Zhi Zhou et al.
AUTOPHAGY (2009)
Phosphorylation of Beclin 1 by DAP-kinase promotes autophagy by weakening its interactions with Bcl-2 and Bcl-X-L
Einat Zalckvar et al.
AUTOPHAGY (2009)
Atg101, a novel mammalian autophagy protein interacting with Atg13
Nao Hosokawa et al.
AUTOPHAGY (2009)
Autophagy: Principles and significance in health and disease
Virginia Todde et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2009)
Selective types of autophagy in yeast
Claudine Kraft et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2009)
Mitophagy
Aviva M. Tolkovsky
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2009)
The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases
Zhenyu Yue et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2009)
Comprehensive comparative-genomic analysis of Type 2 toxin-antitoxin systems and related mobile stress response systems in prokaryotes
Kira S. Makarova et al.
BIOLOGY DIRECT (2009)
Arginine Deiminase as a Novel Therapy for Prostate Cancer Induces Autophagy and Caspase-Independent Apoptosis
Randie H. Kim et al.
CANCER RESEARCH (2009)
The Role of ATF4 Stabilization and Autophagy in Resistance of Breast Cancer Cells Treated with Bortezomib
Manuela Milani et al.
CANCER RESEARCH (2009)
4E-BP Extends Lifespan upon Dietary Restriction by Enhancing Mitochondrial Activity in Drosophila
Brian M. Zid et al.
CELL (2009)
Autophagy Suppresses Tumorigenesis through Elimination of p62
Robin Mathew et al.
CELL (2009)
NBR1 and p62 as cargo receptors for selective autophagy of ubiquitinated targets
Trond Lamark et al.
CELL CYCLE (2009)
The role of autophagy in the heart
K. Nishida et al.
CELL DEATH AND DIFFERENTIATION (2009)
被撤回的出版物: A novel function of poly(ADP-ribose) polymerase-1 in modulation of autophagy and necrosis under oxidative stress (Retracted article. See vol. 17, pg. 1944, 2010)
Q. Huang et al.
CELL DEATH AND DIFFERENTIATION (2009)
Vitamin D3 Induces Autophagy in Human Monocytes/Macrophages via Cathelicidin
Jae-Min Yuk et al.
CELL HOST & MICROBE (2009)
Turnover of organelles by autophagy in yeast
Jean-Claude Farre et al.
CURRENT OPINION IN CELL BIOLOGY (2009)
Autophagy in human type 2 diabetes pancreatic beta cells
M. Masini et al.
DIABETOLOGIA (2009)
XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy
Claudio Hetz et al.
GENES & DEVELOPMENT (2009)
Lifespan extension by suppression of autophagy genes in Caenorhabditis elegans
Yasufumi Hashimoto et al.
GENES TO CELLS (2009)
Cytoplasmic retention of polyglutamine-expanded androgen receptor ameliorates disease via autophagy in a mouse model of spinal and bulbar muscular atrophy
Heather L. Montie et al.
HUMAN MOLECULAR GENETICS (2009)
ULK1•ATG13•FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy
Ian G. Ganley et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Cyclodepsipeptide toxin promotes the degradation of Hsp90 client proteins through chaperone-mediated autophagy
Shensi Shen et al.
JOURNAL OF CELL BIOLOGY (2009)
Desmethylclomipramine induces the accumulation of autophagy markers by blocking autophagic flux
Mario Rossi et al.
JOURNAL OF CELL SCIENCE (2009)
Mammalian macroautophagy at a glance
Brinda Ravikumar et al.
JOURNAL OF CELL SCIENCE (2009)
The Adaptor Protein p62/SQSTM1 Targets Invading Bacteria to the Autophagy Pathway
Yiyu T. Zheng et al.
JOURNAL OF IMMUNOLOGY (2009)
Posttranslational Modification of Ataxin-7 at Lysine 257 Prevents Autophagy-Mediated Turnover of an N-Terminal Caspase-7 Cleavage Fragment
Shona Mookerjee et al.
JOURNAL OF NEUROSCIENCE (2009)
Inhibition of Autophagy Induction Delays Neuronal Cell Loss Caused by Dysfunctional ESCRT-III in Frontotemporal Dementia
Jin-A Lee et al.
JOURNAL OF NEUROSCIENCE (2009)
Beclin 1 Gene Transfer Activates Autophagy and Ameliorates the Neurodegenerative Pathology in α-Synuclein Models of Parkinson's and Lewy Body Diseases
Brian Spencer et al.
JOURNAL OF NEUROSCIENCE (2009)
Endoplasmic Reticulum Stress-Mediated Autophagy/Apoptosis Induced by Capsaicin (8-Methyl-N-vanillyl-6-nonenamide) and Dihydrocapsaicin is Regulated by the Extent of c-Jun NH2-Terminal Kinase/Extracellular Signal-Regulated Kinase Activation in WI38 Lung Epithelial Fibroblast Cells
Seon-Hee Oh et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)
Mapping the Phosphorylation Sites of Ulk1
Frank C. Dorsey et al.
JOURNAL OF PROTEOME RESEARCH (2009)
ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery
Chang Hwa Jung et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
Induction of macroautophagy by heat
Yuanbo Zhao et al.
MOLECULAR BIOLOGY REPORTS (2009)
A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates
Vladimir Kirkin et al.
MOLECULAR CELL (2009)
Autophagy regulates lipid metabolism
Rajat Singh et al.
NATURE (2009)
Induction of autophagy by spermidine promotes longevity
Tobias Eisenberg et al.
NATURE CELL BIOLOGY (2009)
Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex
Yun Zhong et al.
NATURE CELL BIOLOGY (2009)
Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages
Kohichi Matsunaga et al.
NATURE CELL BIOLOGY (2009)
Prokaryotic ubiquitin-like protein (Pup), proteasomes and pathogenesis
K. Heran Darwin
NATURE REVIEWS MICROBIOLOGY (2009)
Dynamics and diversity in autophagy mechanisms: lessons from yeast
Hitoshi Nakatogawa et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Autophagy in neurodegeneration: firefighter and/or incendiarist?
A. Rami
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2009)
Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response
Tatsuya Saitoh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis
Yong Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
A Gene Network Regulating Lysosomal Biogenesis and Function
Marco Sardiello et al.
SCIENCE (2009)
The emerging role of autophagy in Parkinson's disease
Zelda H. Cheung et al.
MOLECULAR BRAIN (2009)
Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
Anne Simonsen et al.
AUTOPHAGY (2008)
The effects of p53 on whole organism longevity are mediated by autophagy
Nektarios Tavernarakis et al.
AUTOPHAGY (2008)
The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates
Karine Lindmo et al.
AUTOPHAGY (2008)
Induction of macroautophagy by exogenously introduced calcium
Wentao Gao et al.
AUTOPHAGY (2008)
Xenophagy in herpes simplex virus replication and pathogenesis
Diane E. Alexander et al.
AUTOPHAGY (2008)
Is the Rsp5 ubiquitin ligase involved in the regulation of ribophagy?
Claudine Kraft et al.
AUTOPHAGY (2008)
The regulation and function of Class III PI3Ks: novel roles for Vps34
Jonathan M. Backer
BIOCHEMICAL JOURNAL (2008)
Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation
Mondira Kundu et al.
BLOOD (2008)
OSU-03012, a Novel Celecoxib Derivative, Induces Reactive Oxygen Species-Related Autophagy in Hepatocellular Carcinoma
Ming Gao et al.
CANCER RESEARCH (2008)
Autophagy in the pathogenesis of disease
Beth Levine et al.
CELL (2008)
Loss of Autophagy Diminishes Pancreatic β Cell Mass and Function with Resultant Hyperglycemia
Hye Seung Jung et al.
CELL METABOLISM (2008)
The role of autophagy in mammalian development: Cell makeover rather than cell death
Francesco Cecconi et al.
DEVELOPMENTAL CELL (2008)
Fragile X syndrome
Kathryn B. Garber et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2008)
Huntington's disease: degradation of mutant huntingtin by autophagy
Sovan Sarkar et al.
FEBS JOURNAL (2008)
Reactive oxygen species and nitric oxide regulate mitochondria-dependent apoptosis and autophagy in evodiamine-treated human cervix carcinoma HeLa cells
Jia Yang et al.
FREE RADICAL RESEARCH (2008)
Aberrant interaction between Parkinson disease-associated mutant UCH-L1 and the lysosomal receptor for chaperone-mediated autophagy
Tomohiro Kabuta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Abl Kinases Regulate Autophagy by Promoting the Trafficking and Function of Lysosomal Components
Gouri Yogalingam et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Wild type α-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells
Tereza Vogiatzi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
Elizabeth L. Axe et al.
JOURNAL OF CELL BIOLOGY (2008)
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
Derek Narendra et al.
JOURNAL OF CELL BIOLOGY (2008)
FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells
Taichi Hara et al.
JOURNAL OF CELL BIOLOGY (2008)
Autophagosome supports coxsackievirus B3 replication in host cells
Jerry Wong et al.
JOURNAL OF VIROLOGY (2008)
The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane
Urmi Bandyopadhyay et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
The TSC1-TSC2 complex is required for proper activation of mTOR complex 2
Jingxiang Huang et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
The Atg8 Conjugation System Is Indispensable for Proper Development of Autophagic Isolation Membranes in Mice
Yu-shin Sou et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
The Atg1 kinase complex is involved in the regulation of protein recruitment to initiate sequestering vesicle formation for nonspecific autophagy in Saccharomyces cerevisiae
Heesun Cheong et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
Beclin 1 Forms Two Distinct Phosphatidylinositol 3-Kinase Complexes with Mammalian Atg14 and UVRAG
Eisuke Itakura et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
AMPK phosphorylation of raptor mediates a metabolic checkpoint
Dana M. Gwinn et al.
MOLECULAR CELL (2008)
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
Tatsuya Saitoh et al.
NATURE (2008)
Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease
Claudine Kraft et al.
NATURE CELL BIOLOGY (2008)
Regulation of autophagy by cytoplasmic p53
Ezgi Tasdemir et al.
NATURE CELL BIOLOGY (2008)
Novel targets for Huntington's disease in an mTOR-independent autophagy pathway
Andrea Williams et al.
NATURE CHEMICAL BIOLOGY (2008)
Protective role of autophagy in neonatal hypoxia-ischemia induced brain injury
Silvia Carloni et al.
NEUROBIOLOGY OF DISEASE (2008)
E2F1 regulates autophagy and the transcription of autophagy genes
S. Polager et al.
ONCOGENE (2008)
Developmental expression of LC3 alpha and beta: Absence of fibronectin or autophagy phenotype in LC3 beta knockout mice
Gordon M. Cann et al.
DEVELOPMENTAL DYNAMICS (2008)
Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis
Miguel A. Sanjuan et al.
NATURE (2007)
ESCRTing proteins in the endocytic pathway
Surai Saksena et al.
TRENDS IN BIOCHEMICAL SCIENCES (2007)
Plant autophagy-more than a starvation response
Diane C. Bassham
CURRENT OPINION IN PLANT BIOLOGY (2007)
Magnolol-induced H460 cells death via autophagy but not apoptosis
Hai-bo Li et al.
ARCHIVES OF PHARMACAL RESEARCH (2007)
Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila
Gabor Juhasz et al.
GENES & DEVELOPMENT (2007)
FoxO3 coordinately activates protein degradation by the Autophagic/Lysosomal and proteasomal pathways in atrophying muscle cells
Jinghui Zhao et al.
CELL METABOLISM (2007)
Small molecule regulators of autophagy identified by an image-based high-throughput screen
Lihong Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis
Yoshinori Takahashi et al.
NATURE CELL BIOLOGY (2007)
Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice
Tohru Kitada et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
The role of autophagy in mitochondria maintenance -: Characterization of mitochondrial functions in autophagy-deficient S-cerevisiae strains
Yong Zhang et al.
AUTOPHAGY (2007)
Selective and non-selective autophagic degradation of mitochondria in yeast
Ingrid Kissova et al.
AUTOPHAGY (2007)
AMP-activated protein kinase -: A universal regulator of autophagy?
Maria Hoyer-Hansen et al.
AUTOPHAGY (2007)
Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: Role of Akt and extracellular signal-regulated kinase signaling pathways
Hiroshi Aoki et al.
MOLECULAR PHARMACOLOGY (2007)
Ambra1 regulates autophagy and development of the nervous system
Gian Maria Fimia et al.
NATURE (2007)
被撤回的出版物: Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/Autophagin-3 (Retracted article. See vol. 294, pg. 1435, 2019)
Guillermo Marino et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Small molecules enhance autophagy and reduce toxicity in Huntington's disease models
Sovan Sarkar et al.
NATURE CHEMICAL BIOLOGY (2007)
Disruption of autophagy results in constitutive oxidative stress in Arabidopsis
Yan Xiang et al.
AUTOPHAGY (2007)
Selective autophagy of the endoplasmic reticulum
Sebastian Bernales et al.
AUTOPHAGY (2007)
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
John D. Rioux et al.
NATURE GENETICS (2007)
The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress
Atsuko Nakai et al.
NATURE MEDICINE (2007)
β-amyloid is a substrate of autophagy in sporadic inclusion body myositis
Jan D. Lunemann et al.
ANNALS OF NEUROLOGY (2007)
The anticancer drug imatinib induces cellular autophagy
A. Ertmer et al.
LEUKEMIA (2007)
Genistein-induced apoptosis and autophagocytosis in ovarian cancer cells
Gabrielle Gossner et al.
GYNECOLOGIC ONCOLOGY (2007)
Autophagy gene-dependent clearance of apoptotic cells during embryonic development
Xueping Qu et al.
CELL (2007)
Arsenic trioxide induces not only apoptosis but also autophagic cell death in leukemia cell lines via up-regulation of Beclin-1
Wenbin Qian et al.
LEUKEMIA RESEARCH (2007)
Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and α-synuclein
Sovan Sarkar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Concanavalin A induces autophagy in hepatoma cells and has a therapeutic effect in a murine in situ hepatoma model
Chih-Peng Chang et al.
HEPATOLOGY (2007)
Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-β, and Bcl-2
Maria Hoyer-Hansen et al.
MOLECULAR CELL (2007)
Nibbling within the nucleus: turnover of nuclear contents
D. Mijaljica et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2007)
Protein dynamics and proteolysis in plant vacuoles
Klaus Muentz
JOURNAL OF EXPERIMENTAL BOTANY (2007)
Degradation of oxidized proteins by autophagy during oxidative stress in Arabidopsis
Yan Xiong et al.
PLANT PHYSIOLOGY (2007)
Advances in Lafora progressive myoclonus epilepsy
Antonio V. Delgado-Escueta
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS (2007)
Self-eating and self-killing: crosstalk between autophagy and apoptosis
M. Chiara Maiuri et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Autophagy and neurodegeneration: when the cleaning crew goes on strike
Marta Martinez-Vicente et al.
LANCET NEUROLOGY (2007)
Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response
Sebastian Bernales et al.
PLOS BIOLOGY (2006)
Pexophagy: Autophagic degradation of peroxisomes
Yasuyoshi Sakai et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2006)
Autophagy is activated for cell survival after endoplasmic reticulum stress
Maiko Ogata et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Hsp90 inhibition results in autophagy-mediated proteasome-independent degradation of IκB kinase (IKK)
Guoliang Qing et al.
CELL RESEARCH (2006)
NF-κB activation represses tumor necrosis factor-α-induced autophagy
Mojgan Djavaheri-Mergny et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Degradation of amyotrophic lateral sclerosis-linked mutant Cu,Zn-superoxide dismutase proteins by macroautophagy and the proteasome
Tomohiro Kabuta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Role of FIP200 in cardiac and liver development and its regulation of TNFα and TSC-mTOR signaling pathways
Boyi Gan et al.
JOURNAL OF CELL BIOLOGY (2006)
Autophagy in cancer: Good, bad, or both?
Melanie M. Hippert et al.
CANCER RESEARCH (2006)
Autophagy in neurons: it is not all about food
Ana Maria Cuervo
TRENDS IN MOLECULAR MEDICINE (2006)
Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes
Andrew R. J. Young et al.
JOURNAL OF CELL SCIENCE (2006)
Human IRGM induces autophagy to eliminate intracellular mycobacteria
Sudha B. Singh et al.
SCIENCE (2006)
Autophagy is disrupted in a knock-in mouse model of juvenile neuronal ceroid lipofuscinosis
Yi Cao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
Kurt Degenhardt et al.
CANCER CELL (2006)
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
Taichi Hara et al.
NATURE (2006)
Loss of autophagy in the central nervous system causes neurodegeneration in mice
Masaaki Komatsu et al.
NATURE (2006)
Sulforaphane causes autophagy to inhibit release of cytochrome c and apoptosis in human prostate cancer cells
Anna Herman-Antosiewicz et al.
CANCER RESEARCH (2006)
Aggresomes and autophagy generate sites for virus replication
T Wileman
SCIENCE (2006)
Rapamycin pre-treatment protects against apoptosis
B Ravikumar et al.
HUMAN MOLECULAR GENETICS (2006)
Assortment of phosphatidylinositol 3-kinase complexes-Atg14p directs association of complex I to the pre-autophagosomal structure in Saccharomyces cerevisiae
K Obara et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
Alterations in degradative pathways and protein aggregation in a neuropathy model based on PMP22 overexpression
J Fortun et al.
NEUROBIOLOGY OF DISEASE (2006)
Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation
L Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
PKR-dependent autophagic degradation of herpes simplex virus type 1
Zsolt Talloczy et al.
AUTOPHAGY (2006)
Autophagy in development and stress responses of plants
DC Bassham et al.
AUTOPHAGY (2006)
The actin cytoskeleton is required for selective types of autophagy, but not nonspecific autophagy, in the yeast Saccharomyces cerevisiae
F Reggiori et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
G Bjorkoy et al.
JOURNAL OF CELL BIOLOGY (2005)
Autophagy in cell death: an innocent convict?
B Levine et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Autophagy and aging -: The importance of maintaining clean cells
Ana Maria Cuervo et al.
AUTOPHAGY (2005)
Microautophagic vacuole invagination requires calmodulin in a Ca2+-independent function
A Uttenweiler et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Lithium induces autophagy by inhibiting inositol monophosphatase
S Sarkar et al.
JOURNAL OF CELL BIOLOGY (2005)
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
S Pattingre et al.
CELL (2005)
Increased susceptibility of cytoplasmic over nuclear polyglutamine aggregates to autophagic degradation
A Iwata et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Autophagic nutrient recycling in Arabidopsis directed by the ATG8 and ATG12 conjugation pathways
AR Thompson et al.
PLANT PHYSIOLOGY (2005)
Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy
Isei Tanida et al.
AUTOPHAGY (2005)
Atg9 cycles between mitochondria and the pre-autophagosomal structure in yeasts
Fulvio Reggiori et al.
AUTOPHAGY (2005)
The NF1 tumor suppressor critically regulates TSC2 and mTOR
CM Johannessen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Autophagy regulates programmed cell death during the plant innate immune response
Y Liu et al.
CELL (2005)
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
M Komatsu et al.
JOURNAL OF CELL BIOLOGY (2005)
Subversion of cellular autophagosomal machinery by RNA viruses
WT Jackson et al.
PLOS BIOLOGY (2005)
Escape of intracellular Shigella from autophagy
M Ogawa et al.
SCIENCE (2005)
Starvation triggers the delivery of the endoplasmic reticulum to the vacuole via autophagy in yeast
M Hamasaki et al.
TRAFFIC (2005)
Autophagy as a cell death and tumor suppressor mechanism
D Gozuacik et al.
ONCOGENE (2004)
Dictyostelium macroautophagy mutants vary in the severity of their developmental defects
GP Otto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells
T Kanzawa et al.
CELL DEATH AND DIFFERENTIATION (2004)
Determination of four sequential stages during microautophagy in vitro
JB Kunz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
RJ Shaw et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Role of Unc51.1 and its binding partners in CNS axon outgrowth
T Tomoda et al.
GENES & DEVELOPMENT (2004)
Trehalose alleviates polyglutamine-mediated pathology in a mouse model of Huntington disease
M Tanaka et al.
NATURE MEDICINE (2004)
Resveratrol-induced autophagocytosis in ovarian cancer cells
AW Opipari et al.
CANCER RESEARCH (2004)
Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes
A Simonsen et al.
JOURNAL OF CELL SCIENCE (2004)
Role and regulation of starvation-induced autophagy in the Drosophila fat body
RC Scott et al.
DEVELOPMENTAL CELL (2004)
The role of autophagy during the early neonatal starvation period
A Kuma et al.
NATURE (2004)
LC3 conjugation system in mammalian autophagy
I Tanida et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
The role of macroautophagy in the ageing process, anti-ageing intervention and age-associated diseases
E Bergamini et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
Regulation and role of autophagy in mammalian cells
AJ Meijer et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
Mechanisms of chaperone-mediated autophagy
AE Majeski et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
Autophagy, proteasomes, lipofuscin, and oxidative stress in the aging brain
JN Keller et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
Arabidopsis homologues of the autophagy protein Atg8 are a novel family of microtubule binding proteins
T Ketelaar et al.
FEBS LETTERS (2004)
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
B Ravikumar et al.
NATURE GENETICS (2004)
Rab7 is required for the normal progression of the autophagic pathway in mammalian cells
MG Gutierrez et al.
JOURNAL OF CELL SCIENCE (2004)
The Ras/cAMP-dependent protein kinase signaling pathway regulates an early step of the autophagy process in Saccharomyces cerevisiae
YV Budovskaya et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Autophagy genes are essential for dauer development and life-span extension in C-elegans
A Meléndez et al.
SCIENCE (2003)
Cannibalism by sporulating bacteria
JE Gonzalez-Pastor et al.
SCIENCE (2003)
α-synuclein is degraded by both autophagy and the proteasome
JL Webb et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The Drosophila homolog of Aut1 is essential for autophagy and development
G Juhász et al.
FEBS LETTERS (2003)
Macroautophagy is required for multicellular development of the social amoeba Dictyostelium discoideum
GP Otto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Piecemeal microautophagy of nucleus in Saccharomyces cerevisiae
P Roberts et al.
MOLECULAR BIOLOGY OF THE CELL (2003)
Mechanism of cargo selection in the cytoplasm to vacuole targeting pathway
T Shintani et al.
DEVELOPMENTAL CELL (2002)
Autophagy in yeast: A review of the molecular machinery
WP Huang et al.
CELL STRUCTURE AND FUNCTION (2002)
The APG8/12-activating enzyme APG7 is required for proper nutrient recycling and senescence in Arabidopsis thaliana
JH Doelling et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Leaf senescence and starvation-induced chlorosis are accelerated by the disruption of an Arabidopsis autophagy gene
H Hanaoka et al.
PLANT PHYSIOLOGY (2002)
Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy
B Ravikumar et al.
HUMAN MOLECULAR GENETICS (2002)
Regulation of starvation- and virus-induced autophagy by the eIF2α kinase signaling pathway
Z Tallóczy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation
K Suzuki et al.
EMBO JOURNAL (2001)
Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I
DJ Katzmann et al.
CELL (2001)
Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells
N Mizushima et al.
JOURNAL OF CELL BIOLOGY (2001)
Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae
A Kihara et al.
JOURNAL OF CELL BIOLOGY (2001)
A ubiquitin-like system mediates protein lipidation
Y Ichimura et al.
NATURE (2000)
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
Y Kabeya et al.
EMBO JOURNAL (2000)
Age-related decline in chaperone-mediated autophagy
AM Cuervo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease)
I Nishino et al.
NATURE (2000)
Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice
Y Tanaka et al.
NATURE (2000)