Highly sensitive and selective naked eye detection of fluoride anion with isatin-thiazole hybrid molecule

The development of simple and cheap sensors/receptors for anion recognition is research area of immense importance in supramolecular chemistry. Among various artificial receptors, the compounds that preferably show visible color changes upon interaction with anions are particularly fascinating. We have designed and synthesized a novel isatin-thiazol hybrid molecule 2 that is found to be a highly selective and sensitive sensor for fluoride anion over the other anions such as Cl, Br, I, PF4, AcO, ClO4, H2PO4 as revealed by the UV-vis and naked eye experiments. The limit of detection (LOD) calculated for this sensor is 0.0044 ppm. (C) 2020 Elsevier Ltd. All rights reserved.