期刊
出版社
ELSEVIER
DOI: 10.1016/j.msec.2019.110104
关键词
Nanoparticles; SPIONs; Fluorescence; Imaging; Silicon quantum dots; Multifunctionality
资金
- Associate Laboratory Research Unit for Green Chemistry - Clean Processes and Technologies - LAQV - FCT/MEC [UID/QUI/50006/2013]
- ERDF under the PT2020 Partnership Agreement [POCI-01-0145-FEDER -007265]
- Proteomass Scientific Society (Portugal)
- FCT/MEC (Portugal), PhD programme in Sustainable Chemistry of FCT-UNL (Portugal) [PD/BD/142865/2018]
- FCT/MEC (Portugal) [CEECIND/00648/2017]
- Fundação para a Ciência e a Tecnologia [PD/BD/142865/2018] Funding Source: FCT
Multifunctional nanoparticles have emerged as an outstanding candidate for a new generation of biomedical applications, mainly due to their remarkable properties and biocompatibility. Individual reports on multi-metal, semiconducting and superparamagnetic nanoparticles (SPIONs), elucidating on each's unique intrinsic properties, have demonstrated that the biological application of such materials is highly dependent of their size, shape, surface nature and core nature. However, reviews combining nanoparticles with multiple properties, as fluorescence and paramagnetism, as well as, biocompatibility, toxicology and biodegradability are yet seldom. This review highlights the highest output advances, of the last decade, on synthetic procedures for the design of multifunctional magneto-luminescent hybrid nanosystems based on quantum dots, SPIONs and mesoporous silica nanoparticles, as well as, surface modifications and their role for biological applications.
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