期刊
出版社
ELSEVIER
DOI: 10.1016/j.msec.2019.110105
关键词
Collagen; Collagen fibers; Wet spinning; Fiber based scaffold
资金
- German Federal Ministry of Education and Research (BMBF, Programm Unternehmen Region, Zentren fur Innovationskompetenz) [03Z2EI1, 03Z2ES1, 03Z22EB1]
- European Regional Development Fund [ERDF/EFRE 100232736]
- program The Central Innovation Programme for SMEs from funds of the Federal Ministry for Economic Affairs and Energy (BMWi) [ZF4008306AW6]
The benefits of fiber based implants and scaffolds for tissue engineering applications are their anisotropic, highly porous, and controllable macro-, micro-, and nanostructure. Collagen is one of the most commonly used material for the fabrication of scaffolds, as this biopolymer is present in the natural extracellular matrix. For textile processing and textile scaffold fabrication methods, multifilament yarns are required, however, only monofilaments can be generated by state-of-the-art collagen spinning. Hence, the research presented in here aimed at the development of a collagen multifilament wet-spinning process in reproducible quality as well as the characterization of non-crosslinked and crosslinked wet-spun multifilament yams. Wet spun collagen yarns were comprised of 6 single filaments each having a fineness of 5 tex and a diameter of 80 mu m. The tensile strength of the glutaraldehyde crosslinked yams was 169 MPa (Young's modulus 3534 MPa) in the dry state and 40 MPa (Young's modulus 281 MPa) in the wet state. Furthermore, wet spun collagen filaments showed a characteristic fibrillar structure, which was similar the morphological structure of natural collagen fibers. The textile processing of collagen multifilament yarn was demonstrated by means of knitting technology.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据