期刊
MARINE DRUGS
卷 17, 期 12, 页码 -出版社
MDPI
DOI: 10.3390/md17120706
关键词
Junceella fragilis; fragilide; briarane; gorgonian; junceellonoid; junceellin; iNOS
资金
- NMMBA
- NDHU
- Kaohsiung Armed Forces General Hospital [108-33]
- Ministry of Science and Technology, Taiwan [MOST 108-2320B-276-001, 104-2320-B-291-001-MY3, 107-2320-B-291-001-MY3]
Three new 11,20-epoxybriaranes-fragilides U-W (1-3), as well as two known metabolites, junceellonoid D (4) and junceellin (5), were obtained from the octocoral Junceella fragilis. The structures of briaranes 1-3 were elucidated by spectroscopic methods and briaranes 3 and 5 displayed inhibition effects on inducible nitric oxide synthase (iNOS) release from RAW264.7.
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