期刊
MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE
卷 33, 期 1, 页码 141-161出版社
SPRINGER
DOI: 10.1007/s10334-019-00800-z
关键词
MRI; Arterial spin labelling; Kidney; Perfusion; Renal blood flow
资金
- Academy of Medical Sciences [SGL015\\1019] Funding Source: Medline
- European Cooperation in Science and Technology [CA16103] Funding Source: Medline
- Kidney Research UK [ST1/2013, IN_011_20170303] Funding Source: Medline
- Medical Research Council [MR/R02264x/1] Funding Source: Medline
- Ministerio de Economía y Competitividad [IEDI-2017-00826] Funding Source: Medline
- National Institute for Health Research [CL-2014-06-003] Funding Source: Medline
- NCI NIH HHS [R01CA154475, P50CA196516, R01 CA154475, P50 CA196516, U01 CA207091, U01CA207091] Funding Source: Medline
- Netherlands Organization for Scientific Research (NL) [14951] Funding Source: Medline
- NIDDK NIH HHS [R01 DK109349, 1F32DK109591] Funding Source: Medline
- UCL Leonard Wolfson Experimental Neurology Centre (GB) [PR/ylr/18575] Funding Source: Medline
- Great Ormond Street Hospital Charity [V0318] Funding Source: Medline
- Innovative Medicines Initiative [115974] Funding Source: Medline
- MRC [MR/R02264X/1] Funding Source: UKRI
Objectives This study aimed at developing technical recommendations for the acquisition, processing and analysis of renal ASL data in the human kidney at 1.5 T and 3 T field strengths that can promote standardization of renal perfusion measurements and facilitate the comparability of results across scanners and in multi-centre clinical studies. Methods An international panel of 23 renal ASL experts followed a modified Delphi process, including on-line surveys and two in-person meetings, to formulate a series of consensus statements regarding patient preparation, hardware, acquisition protocol, analysis steps and data reporting. Results Fifty-nine statements achieved consensus, while agreement could not be reached on two statements related to patient preparation. As a default protocol, the panel recommends pseudo-continuous (PCASL) or flow-sensitive alternating inversion recovery (FAIR) labelling with a single-slice spin-echo EPI readout with background suppression and a simple but robust quantification model. Discussion This approach is considered robust and reproducible and can provide renal perfusion images of adequate quality and SNR for most applications. If extended kidney coverage is desirable, a 2D multislice readout is recommended. These recommendations are based on current available evidence and expert opinion. Nonetheless they are expected to be updated as more data become available, since the renal ASL literature is rapidly expanding.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据