期刊
MACROMOLECULAR BIOSCIENCE
卷 20, 期 4, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/mabi.201900370
关键词
hemostasis; hemostatic strategy; performance; polysaccharides
资金
- Wenzhou Science and Technology Major Project [ZS2017023, ZY2019018]
- Wenzhou Science and Technology Public Project [G20180029]
- Wenzhou Institute, University of Chinese Academy of Sciences startup fund [WIUCASQD2019006]
- Zhejiang Province Welfare Technology Applied Research Project [LGF20C100002]
- Scientific Research Fund of National Health Commission [WKJ-ZJ-1707]
- Wenzhou Longwan District (High-tech Zone) Science and Technology Project [2018KG10Z]
- Project of State Key Laboratory of Ophthalmology, Optometry and Visual Science, Wenzhou Medical University [K171204]
- State Key Project of Research and Development [2016YFC1100300]
- National Natural Science Foundation of China [31370969, 51673145]
- International Science & Technology Cooperation Program of China [2013DFG52040]
Bleeding complications usually cause significant morbidity and mortality in civilian and military populations. In clinical application, hemostatic sponges, gauzes, hydrogel, and bandages are widely used as the traditional effective hemostatic products for hemorrhage. However, the traditional hemostatic devices or agents cannot meet the requirement for treatment of massive bleeding. Therefore, the excellent hemostatic performance of hemostatic products are of great significance for saving lives. Natural polysaccharides, as the main chemical component, have been widely used in the preparation of hemostasis due to their perfect biocompatibility and biodegradability. Polysaccharide based hemostatic products are available in variety of forms, such as, hydrogel, sponges, gauze and microspheres. The purpose of the present review is to report the research progress on polysaccharide hemostatic products and technology.
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