期刊
JOURNAL OF VIROLOGY
卷 94, 期 8, 页码 -出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.02120-19
关键词
TNT; antibodies; intercellular; spread; tunneling nanotubes; virus
类别
资金
- FWO-Vlaanderen [G019617N, G060119N]
- Special Research Fund of Ghent University (GOA grant) [01G01317]
Tunneling nanotubes (TNTs) are actin-based intercellular conduits that connect distant cells and allow intercellular transfer of molecular information, including genetic information, proteins, lipids, and even organelles. Besides providing a means of intercellular communication, TNTs may also be hijacked by pathogens, particularly viruses, to facilitate their spread. Viruses of many different families, including retroviruses, herpesviruses, orthomyxoviruses, and several others have been reported to trigger the formation of TNTs or TNT-like structures in infected cells and use these structures to efficiently spread to uninfected cells. In the current review, we give an overview of the information that is currently available on viruses and TNT-like structures, and we discuss some of the standing questions in this field.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据