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Rapid nongenomic effects of aldosterone on the renal vasculature in humans
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HYPERTENSION (2006)
Double-blind, placebo-controlled study on the effect of the aldosterone receptor antagonist spironolactone in patients who have persistent proteinuria and are on long-term angiotensin-converting enzyme inhibitor therapy, with or without an angiotensin II receptor blocker
Anastasia Chrysostomou et al.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)
Chronic hypoxia and tubulointerstitial injury: A final common pathway to end-stage renal failure
Masaomi Nangaku
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)
Aldosterone blockade attenuates urinary monocyte chemoattractant protein-1 and oxidative stress in patients with type 2 diabetes complicated by diabetic nephropathy
Kohzo Takebayashi et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2006)
Molecular mechanisms and therapeutic strategies of chronic renal injury: Renoprotective effects of aldosterone blockade
A Nishiyama et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2006)
Aldosterone blockage in proliferative glomerulonephritis prevents not only fibrosis, but proliferation as well
Mustafa Gullulu et al.
RENAL FAILURE (2006)
Renocortical mRNA expression of vasoactive factors during spironolactone protective effect in chronic cyclosporine nephrotoxicity
JM Pérez-Rojas et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2005)
Regression of existing glomerulosclerosis by inhibition of aldosterone
JC Aldigier et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2005)
Aldosterone stimulates collagen gene expression and synthesis via activation of ERK1/2 in rat renal fibroblasts
Y Nagai et al.
HYPERTENSION (2005)
Low-renin hypertension with relative aldosterone excess is associated with impaired NO-mediated vasodilation
SJ Duffy et al.
HYPERTENSION (2005)
Increased expression of mineralocorticoid effector mechanisms in kidney biopsies of patients with heavy proteinuria
M Quinkler et al.
CIRCULATION (2005)
Eplerenone reduces oxidative stress and enhances eNOS in SHR:: Vascular functional and structural consequences
D Sanz-Rosa et al.
ANTIOXIDANTS & REDOX SIGNALING (2005)
Aldosterone nongenomically worsens ischemia via protein kinase C-dependent pathways in hypoperfused canine hearts
M Fujita et al.
HYPERTENSION (2005)
Primary hyperaldosteronism in the cat: a series of 13 cases
R Andrew et al.
JOURNAL OF FELINE MEDICINE AND SURGERY (2005)
Population-based drug-induced agranulocytosis
L Ibáñez et al.
ARCHIVES OF INTERNAL MEDICINE (2005)
Involvement of aldosterone and mineralocorticoid receptors in rat mesangial cell proliferation and deformability
A Nishiyama et al.
HYPERTENSION (2005)
SGK1: A rapid aldosterone-induced regulator of renal sodium reabsorption
JA McCormick et al.
PHYSIOLOGY (2005)
Eplerenone shows renoprotective effect by reducing LOX-1-mediated adhesion molecule, PKCε-MAPK-p90RSK, and rho-kinase pathway
N Kobayashi et al.
HYPERTENSION (2005)
Angiotensin II and aldosterone regulate gene transcription via functional mineralocortocoid receptors in human coronary artery smooth muscle cells
IZ Jaffe et al.
CIRCULATION RESEARCH (2005)
Eplerenone blocks nongenomic effects of aldosterone on the Na+/H+ exchanger, intracellular Ca2+ levels, and vasoconstriction in mesenteric resistance vessels
L Michea et al.
ENDOCRINOLOGY (2005)
Effects of aldosterone and mineralocorticoid receptor blockade on intracellular electrolytes
M Wehling
HEART FAILURE REVIEWS (2005)
Pharmacokinetics and pharmacodynamics of mineralocorticoid blocking agents and their effects on potassium homeostasis
D Sica
HEART FAILURE REVIEWS (2005)
Primary hyperaldosteronism, a mediator of progressive renal disease in cats
S Javadi et al.
DOMESTIC ANIMAL ENDOCRINOLOGY (2005)
Local renal aldosterone system and its regulation by salt, diabetes, and angiotensin II type 1 receptor
C Xue et al.
HYPERTENSION (2005)
Antiproteinuric effects of mineralocorticoid receptor blockade in patients with chronic renal disease
A Sato et al.
AMERICAN JOURNAL OF HYPERTENSION (2005)
Possible contributions of reactive oxygen species and mitogen-activated protein kinase to renal injury in aldosterone/salt-induced hypertensive rats
A Nishiyama et al.
HYPERTENSION (2004)
Aldosterone-induced vasculopathy
AD Struthers
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2004)
Blood pressure assessment in healthy cats and cats with hypertensive retinopathy
J Sansom et al.
AMERICAN JOURNAL OF VETERINARY RESEARCH (2004)
Endothelium-derived nitric oxide modulates vascular action of aldosterone in renal arteriole
S Arima et al.
HYPERTENSION (2004)
Characterisatioti of 11β-hydroxysteroid dehydrogenases in feline kidney and liver
L Schipper et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2004)
Spironolactone prevents early renal injury in streptozotocin-induced diabetic rats
G Fujisawa et al.
KIDNEY INTERNATIONAL (2004)
Rapid non-genomic effects of aldosterone on rodent vascular function
TR Uhrenholt et al.
ACTA PHYSIOLOGICA SCANDINAVICA (2004)
Spironolactone in combination with cilazapril ameliorates proteinuria and renal interstitial fibrosis in rats with anti-thy-1 irreversible nephritis
M Asai et al.
HYPERTENSION RESEARCH (2004)
Evaluation of a technique of inducing hypertensive renal insufficiency in cats
S Mathur et al.
AMERICAN JOURNAL OF VETERINARY RESEARCH (2004)
Effects of spironolactone on endothelial function, vascular angiotensin converting enzyme activity, and other prognostic markers in patients with mild heart failure already taking optimal treatment
JE Macdonald et al.
HEART (2004)
Aldosterone in the development and progression of renal injury
NK Hollenberg
KIDNEY INTERNATIONAL (2004)
NO bioavailability, endothelial dysfunction, and acute renal failure: New insights into pathophysiology
MS Goligorsky et al.
SEMINARS IN NEPHROLOGY (2004)
Impaired endothelium-dependent flow-mediated vasodilation in hypertensive subjects with hyperaldosteronism
MK Nishizaka et al.
CIRCULATION (2004)
Aldosterone escape during blockade of the renin-angiotensin-aldosterone system in diabetic nephropathy is associated with enhanced decline in glomerular filtration rate
KJ Schjoedt et al.
DIABETOLOGIA (2004)
Effects of dietary sodium chloride intake on renal function and blood pressure in cats with normal and reduced renal function
C Buranakarl et al.
AMERICAN JOURNAL OF VETERINARY RESEARCH (2004)
被撤回的出版物: The effect of spironolactone, cilazapril and their combination on albuminuria in patients with hypertension and diabetic nephropathy is independent of blood pressure reduction: a randomized controlled study (Retracted article see vol 23, pg 818, 2006)
R Rachmani et al.
DIABETIC MEDICINE (2004)
Human endothelium:: Target for aldosterone
H Oberleithner et al.
HYPERTENSION (2004)
Aldosterone regulates vascular reactivity - Short-term effects mediated by phosphatidylinositol 3-kinase-dependent nitric oxide synthase activation
SL Liu et al.
CIRCULATION (2003)
Aldosterone stimulates epidermal growth factor receptor expression
AW Krug et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Early transcriptional effects of aldosterone in a mouse inner medullary collecting duct cell line
ML Gumz et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2003)
Nongenomic vascular action of aldosterone in the glomerular microcirculation
S Arima et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2003)
Endothelin antagonism on aldosterone-induced oxidative stress and vascular remodeling
Q Pu et al.
HYPERTENSION (2003)
Aldosterone: Direct effects on and production by the heart
PC White
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2003)
Effects of the selective aldosterone blocker eplerenone versus the calcium antagonist amlodipine in systolic hypertension
WB White et al.
HYPERTENSION (2003)
Aldosterone/salt induces renal inflammation and fibrosis in hypertensive rats
ER Blasi et al.
KIDNEY INTERNATIONAL (2003)
Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction
B Pitt et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
Effectiveness of aldosterone blockade in patients with diabetic nephropathy
A Sato et al.
HYPERTENSION (2003)
Therapeutic benefit of spironolactone in experimental chronic cyclosporine A nephrotoxicity
I Feria et al.
KIDNEY INTERNATIONAL (2003)
Aldosterone-induced inflammation in the rat heart - Role of oxidative stress
Y Sun et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Spironolactone improves angiotensin-induced vascular changes and oxidative stress
A Virdis et al.
HYPERTENSION (2002)
Aldosterone induces acute endothelial dysfunction in vivo in humans:: evidence for an aldosterone-induced vasculopathy
CAJ Farquharson et al.
CLINICAL SCIENCE (2002)
Prevalence of systolic hypertension in cats with chronic renal failure at initial evaluation
HM Syme et al.
JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION (2002)
Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease
T Heitzer et al.
CIRCULATION (2001)
Prognostic significance of endothelial dysfunction in hypertensive patients
F Perticone et al.
CIRCULATION (2001)
Effects of the angiotensin converting enzyme inhibitor benazepril in cats with induced renal insufficiency
SA Brown et al.
AMERICAN JOURNAL OF VETERINARY RESEARCH (2001)
Aldosterone: A mediator of myocardial necrosis and renal arteriopathy
R Rocha et al.
ENDOCRINOLOGY (2000)
Aldosterone modulates plasminogen activator inhibitor-1 and glomerulosclerosis in vivo
NJ Brown et al.
KIDNEY INTERNATIONAL (2000)
Expression of 11β-hydroxylase and aldosterone synthase genes in the rat brain
SM MacKenzie et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2000)
Survival of cats with naturally occurring chronic renal failure: effect of dietary management
J Elliott et al.
JOURNAL OF SMALL ANIMAL PRACTICE (2000)
Local angiotensin II and transforming growth factor-β1 in renal fibrosis of rats
Y Sun et al.
HYPERTENSION (2000)
Expression of alpha-smooth muscle actin and fibronectin in tubulointerstitial lesions of cats with chronic renal failure
K Sawashima et al.
AMERICAN JOURNAL OF VETERINARY RESEARCH (2000)