期刊
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
卷 75, 期 2, 页码 222-232出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jacc.2019.11.013
关键词
atrial failure; atrial fibrillation; atrial function; heart failure; interatrial block; stroke
资金
- Instituto de Salud Carlos III, Ministerio de Economia y Competitividad, Spain [PI18/01227]
- La MARATO - TV3 [201527]
- CIBER Cardiovascular [CB16/11/00403]
Atrial dysfunction has been widely considered a marker or consequence of other cardiac conditions rather than the cause itself. Here, we propose the term atrial failure as a clinically relevant entity, defined as any atrial dysfunction causing impaired heart performance, symptoms, and worsening quality of life or life expectancy. Aspects of the etiology, mechanisms, and consequences of atrial failure are discussed. Recent advances in cardiac electrophysiology and imaging have improved our understanding of the highly complex atrial anatomy and function, underlying the paramount importance of the atria in optimal heart performance. It is time to reappraise the concept of the failing atrium as a primary cause or aggravating factor of the symptoms in many of our patients. The concept of atrial failure may foster basic and translational research to gain a better understanding of how to identify and manage atrial dysfunction. (C) 2020 by the American College of Cardiology Foundation.
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